Project measure / variable:   Schoonjans1   TCDCA_plasma_t0_HFD

ID, description, units MPD:112671   TCDCA_plasma_t0_HFD   plasma bile acid taurochenodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid taurochenodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means28.041   ng/mL
Median of the strain means23.227   ng/mL
SD of the strain means± 18.724
Coefficient of variation (CV)0.6677
Min–max range of strain means6.5893   –   102.3   ng/mL
Mean sample size per strain4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 50099.2427 1431.4069 1.7773 0.0117
Residuals 121 97451.466 805.384


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 6.7362 3.1348   5 1.4019 0.4654 3.164, 11.407 -1.14
BXD100 m 14.733 10.702   9 3.5674 0.7264 6.262, 38.618 -0.71
BXD11 m 31.875 6.6179   3 3.8208 0.2076 26.454, 39.25 0.2
BXD12 m 15.383 7.6078   3 4.3924 0.4945 9.186, 23.874 -0.68
BXD27 m 48.19 32.067   5 14.341 0.6654 15.84, 86.89 1.08
BXD32 m 9.495 3.9257   4 1.9628 0.4134 5.306, 13.208 -0.99
BXD34 m 19.537 10.312   4 5.1559 0.5278 12.404, 34.784 -0.45
BXD39 m 58.52 58.28   3 33.649 0.996 23.67, 125.8 1.63
BXD40 m 23.456 4.2238   4 2.1119 0.1801 19.098, 29.234 -0.24
BXD43 m 8.1116 4.2206   5 1.8875 0.5203 4.22, 14.174 -1.06
BXD45 m 18.838 6.4624   5 2.8901 0.3431 10.948, 28.492 -0.49
BXD48 m 31.348 19.715   5 8.8169 0.6289 10.994, 63.71 0.18
BXD48a m 102.3 96.54   4 48.272 0.9441 22.748, 242.2 3.97
BXD49 m 28.253 27.61   5 12.348 0.9772 11.584, 77.28 0.01
BXD51 m 54.47 17.751   3 10.249 0.3259 35.148, 70.06 1.41
BXD53 m 36.093 14.461   5 6.4673 0.4007 23.204, 53.63 0.43
BXD55 m 17.181 5.4704   5 2.4464 0.3184 11.14, 25.968 -0.58
BXD6 m 53.66 96.88   5 43.326 1.8054 4.39, 226.6 1.37
BXD62 m 28.56 8.3101   4 4.1551 0.291 20.58, 37.95 0.03
BXD63 m 34.436 9.2304   5 4.1279 0.268 23.67, 47.258 0.34
BXD64 m 27.464 21.974   5 9.8271 0.8001 10.824, 65.62 -0.03
BXD66 m 22.115 11.908   3 6.875 0.5384 11.196, 34.812 -0.32
BXD67 m 20.786 13.074   5 5.8469 0.629 10.776, 43.566 -0.39
BXD69 m 24.118 10.736   4 5.3678 0.4451 10.984, 36.858 -0.21
BXD73 m 6.5893 2.8151   3 1.6253 0.4272 3.97, 9.566 -1.15
BXD75 m 44.545 21.54   4 10.77 0.4836 18.176, 67.98 0.88
BXD77 m 20.41 23.775   5 10.632 1.1649 4.572, 62.44 -0.41
BXD79 m 45.699 20.658   5 9.2386 0.452 19.25, 72.07 0.94
BXD8 m 19.339 20.5   3 11.836 1.06 7.032, 43.004 -0.46
BXD81 m 20.133 19.325   5 8.6423 0.9599 5.918, 53.17 -0.42
BXD84 m 14.49 10.427   5 4.6631 0.7196 6.628, 32.042 -0.72
BXD87 m 14.095 7.3343   4 3.6672 0.5204 5.59, 22.72 -0.74
BXD89 m 24.066 6.3407   5 2.8357 0.2635 13.324, 28.408 -0.21
BXD90 m 22.999 7.381   4 3.6905 0.3209 17.34, 33.454 -0.27
C57BL/6J m 31.597 17.265   3 9.9678 0.5464 20.196, 51.46 0.19
DBA/2J m 9.8707 2.5691   3 1.4832 0.2603 6.914, 11.558 -0.97


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 6.7362 12.6916036531 31.8625770004 -18.3901770004
BXD100 m 14.7328888889 9.4597628373 33.460984556 -3.9952067782
BXD11 m 31.8753333333 16.3847898617 64.3133465578 -0.5626798911
BXD12 m 15.3833333333 16.3847898617 47.8213465578 -17.0546798911
BXD27 m 48.1904 12.6916036531 73.3167770004 23.0640229996
BXD32 m 9.495 14.1896442559 37.5871435006 -18.5971435006
BXD34 m 19.537 14.1896442559 47.6291435006 -8.5551435006
BXD39 m 58.5166666667 16.3847898617 90.9546798911 26.0786534422
BXD40 m 23.4555 14.1896442559 51.5476435006 -4.6366435006
BXD43 m 8.1116 12.6916036531 33.2379770004 -17.0147770004
BXD45 m 18.838 12.6916036531 43.9643770004 -6.2883770004
BXD48 m 31.3476 12.6916036531 56.4739770004 6.2212229996
BXD48a m 102.2595 14.1896442559 130.3516435006 74.1673564994
BXD49 m 28.2532 12.6916036531 53.3795770004 3.1268229996
BXD51 m 54.466 16.3847898617 86.9040132244 22.0279867756
BXD53 m 36.093 12.6916036531 61.2193770004 10.9666229996
BXD55 m 17.1812 12.6916036531 42.3075770004 -7.9451770004
BXD6 m 53.66234 12.6916036531 78.7887170004 28.5359629996
BXD62 m 28.5605 14.1896442559 56.6526435006 0.4683564994
BXD63 m 34.4364 12.6916036531 59.5627770004 9.3100229996
BXD64 m 27.4644 12.6916036531 52.5907770004 2.3380229996
BXD66 m 22.1153333333 16.3847898617 54.5533465578 -10.3226798911
BXD67 m 20.7864 12.6916036531 45.9127770004 -4.3399770004
BXD69 m 24.118 14.1896442559 52.2101435006 -3.9741435006
BXD73 m 6.5893333333 16.3847898617 39.0273465578 -25.8486798911
BXD75 m 44.545 14.1896442559 72.6371435006 16.4528564994
BXD77 m 20.4096 12.6916036531 45.5359770004 -4.7167770004
BXD79 m 45.6988 12.6916036531 70.8251770004 20.5724229996
BXD8 m 19.3393333333 16.3847898617 51.7773465578 -13.0986798911
BXD81 m 20.1328 12.6916036531 45.2591770004 -4.9935770004
BXD84 m 14.49 12.6916036531 39.6163770004 -10.6363770004
BXD87 m 14.0945 14.1896442559 42.1866435006 -13.9976435006
BXD89 m 24.0656 12.6916036531 49.1919770004 -1.0607770004
BXD90 m 22.9995 14.1896442559 51.0916435006 -5.0926435006
C57BL/6J m 31.5966666667 16.3847898617 64.0346798911 -0.8413465578
DBA/2J m 9.8706666667 16.3847898617 42.3086798911 -22.5673465578




  GWAS USING LINEAR MIXED MODELS