Project measure / variable:   Schoonjans1   CDCA_plasma_t0_CD

ID, description, units MPD:112656   CDCA_plasma_t0_CD   plasma bile acid chenodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min   [ng/mL]  CD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid chenodeoxycholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means3.6581   ng/mL
Median of the strain means1.6309   ng/mL
SD of the strain means± 4.2951
Coefficient of variation (CV)1.1741
Min–max range of strain means0.042   –   20.592   ng/mL
Mean sample size per strain4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 34 2978.0129 87.5886 3.7284 < 0.0001
Residuals 126 2960.0175 23.4922


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 4.1978 8.7143   5 3.8972 2.0759 0.128, 19.785 0.13
BXD100 m 1.2844 1.2245   5 0.54762 0.9534 0.388, 3.414 -0.55
BXD11 m 0.855 0.36343   4 0.18171 0.4251 0.448, 1.324 -0.65
BXD12 m 4.8647 4.0071   3 2.3135 0.8237 1.286, 9.194 0.28
BXD27 m 1.429 1.1117   4 0.55585 0.778 0.802, 3.094 -0.52
BXD32 m 5.0288 6.3052   5 2.8198 1.2538 1.25, 16.134 0.32
BXD34 m 5.3592 3.2823   5 1.4679 0.6125 1.5, 10.116 0.4
BXD39 m 1.062 1.1624   3 0.67111 1.0945 0.37, 2.404 -0.6
BXD40 m 13.806 9.415   4 4.7075 0.682 1.4, 24.272 2.36
BXD43 m 1.9173 1.056   6 0.43111 0.5508 1.064, 3.452 -0.41
BXD45 m 6.476 10.974   4 5.487 1.6946 0.586, 22.926 0.66
BXD48 m 1.4504 0.52213   5 0.23351 0.36 0.868, 2.282 -0.51
BXD48a m 2.187 0.67252   4 0.33626 0.3075 1.508, 3.1 -0.34
BXD49 m 7.1376 5.2763   5 2.3596 0.7392 0.66, 11.994 0.81
BXD51 m 1.5096 0.61349   5 0.27436 0.4064 0.838, 2.166 -0.5
BXD53 m 1.798 3.2236   4 1.6118 1.7929 0.112, 6.632 -0.43
BXD55 m 6.608 4.2296   5 1.8915 0.6401 3.088, 12.566 0.69
BXD6 m 20.592 14.78   5 6.6097 0.7178 5.354, 37.18 3.94
BXD62 m 1.1796 0.45031   5 0.20139 0.3818 0.536, 1.61 -0.58
BXD63 m 0.854 0.50788   4 0.25394 0.5947 0.52, 1.61 -0.65
BXD64 m 0.5224 0.17606   5 0.07874 0.337 0.25, 0.742 -0.73
BXD66 m 1.162 0.42509   5 0.19011 0.3658 0.748, 1.654 -0.58
BXD67 m 0.384 0.19821   4 0.09911 0.5162 0.23, 0.674 -0.76
BXD69 m 0.7168 0.3117   5 0.1394 0.4349 0.368, 1.194 -0.68
BXD73 m 7.0615 9.4699   4 4.735 1.3411 0.37, 20.858 0.79
BXD75 m 2.6393 1.1939   5 0.53394 0.4524 1.074, 4.126 -0.24
BXD77 m 10.697 6.5447   5 2.9269 0.6118 2.908, 19.4 1.64
BXD79 m 0.3168 0.16951   5 0.07581 0.5351 0.104, 0.56 -0.78
BXD8 m 0.9776 0.61436   5 0.27475 0.6284 0.516, 2.018 -0.62
BXD81 m 1.6722 1.6553   3 0.95569 0.9899 0.436, 3.5528 -0.46
BXD84 m 0.042 0.0   1   0.0 0.0 0.042, 0.042 -0.84
BXD87 m 5.4312 4.3671   5 1.953 0.8041 1.946, 13.03 0.41
BXD89 m 1.1877 0.57765   6 0.23582 0.4864 0.51, 2.16 -0.58
BXD90 m 1.5896 1.4264   5 0.63789 0.8973 0.526, 4.046 -0.48
C57BL/6J m 6.7412 5.8838   5 2.6313 0.8728 1.062, 16.278 0.72
DBA/2J m 0.954 1.1475   4 0.57376 1.2028 0.24, 2.662 -0.63


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 4.1978 2.1675886244 8.4873941649 -0.0917941649
BXD100 m 1.2844 2.1675886244 5.5739941649 -3.0051941649
BXD11 m 0.855 2.4234377557 5.6509120743 -3.9409120743
BXD12 m 4.8646666667 2.7983448813 10.4025089209 -0.6731755876
BXD27 m 1.429 2.4234377557 6.2249120743 -3.3669120743
BXD32 m 5.0288 2.1675886244 9.3183941649 0.7392058351
BXD34 m 5.3592 2.1675886244 9.6487941649 1.0696058351
BXD39 m 1.062 2.7983448813 6.5998422543 -4.4758422543
BXD40 m 13.8055 2.4234377557 18.6014120743 9.0095879257
BXD43 m 1.9173333333 1.9787286416 5.8331791445 -1.9985124778
BXD45 m 6.476 2.4234377557 11.2719120743 1.6800879257
BXD48 m 1.4504 2.1675886244 5.7399941649 -2.8391941649
BXD48a m 2.187 2.4234377557 6.9829120743 -2.6089120743
BXD49 m 7.1376 2.1675886244 11.4271941649 2.8480058351
BXD51 m 1.5096 2.1675886244 5.7991941649 -2.7799941649
BXD53 m 1.798 2.4234377557 6.5939120743 -2.9979120743
BXD55 m 6.608 2.1675886244 10.8975941649 2.3184058351
BXD6 m 20.5916 2.1675886244 24.8811941649 16.3020058351
BXD62 m 1.1796 2.1675886244 5.4691941649 -3.1099941649
BXD63 m 0.854 2.4234377557 5.6499120743 -3.9419120743
BXD64 m 0.5224 2.1675886244 4.8119941649 -3.7671941649
BXD66 m 1.162 2.1675886244 5.4515941649 -3.1275941649
BXD67 m 0.384 2.4234377557 5.1799120743 -4.4119120743
BXD69 m 0.7168 2.1675886244 5.0063941649 -3.5727941649
BXD73 m 7.0615 2.4234377557 11.8574120743 2.2655879257
BXD75 m 2.6393 2.1675886244 6.9288941649 -1.6502941649
BXD77 m 10.6968 2.1675886244 14.9863941649 6.4072058351
BXD79 m 0.3168 2.1675886244 4.6063941649 -3.9727941649
BXD8 m 0.9776 2.1675886244 5.2671941649 -3.3119941649
BXD81 m 1.6722 2.7983448813 7.2100422543 -3.8656422543
BXD87 m 5.4312 2.1675886244 9.7207941649 1.1416058351
BXD89 m 1.1876666667 1.9787286416 5.1035124778 -2.7281791445
BXD90 m 1.5896 2.1675886244 5.8791941649 -2.6999941649
C57BL/6J m 6.7412 2.1675886244 11.0307941649 2.4516058351
DBA/2J m 0.954 2.4234377557 5.7499120743 -3.8419120743




  GWAS USING LINEAR MIXED MODELS