Project measure / variable:   Schoonjans1   CA_plasma_t0_HFD

ID, description, units MPD:112655   CA_plasma_t0_HFD   plasma bile acid cholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min   [ng/mL]  HFD  
high-fat diet study
Data set, strains Schoonjans1   BXD w/par   36 strains     sex: m     age: 20wks
Procedure biomarker quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Schoonjans1 - plasma bile acid cholic acid amount, glucose kinetic test, at 20 wks of age, at 0 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means23.868   ng/mL
Median of the strain means20.709   ng/mL
SD of the strain means± 22.015
Coefficient of variation (CV)0.9224
Min–max range of strain means1.4488   –   73.61   ng/mL
Mean sample size per strain4.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 35 72694.1682 2076.9762 1.0479 0.4129
Residuals 115 227935.1108 1982.0444


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 1.4488 0.51908   5 0.23214 0.3583 0.854, 2.0179 -1.02
BXD100 m 2.4987 3.2588   6 1.3304 1.3042 0.374, 8.838 -0.97
BXD11 m 12.039 9.0523   3 5.2263 0.7519 6.564, 22.488 -0.54
BXD12 m 8.614 10.227   3 5.9045 1.1872 1.554, 20.342 -0.69
BXD27 m 70.38 133.6   5 59.75 1.8982 0.966, 308.6 2.11
BXD32 m 12.806 11.347   4 5.6734 0.8861 2.794, 27.27 -0.5
BXD34 m 27.444 34.56   4 17.28 1.2593 7.456, 79.14 0.16
BXD39 m 44.657 38.45   3 22.199 0.861 2.422, 77.63 0.94
BXD40 m 21.365 28.417   4 14.208 1.3301 4.95, 63.82 -0.11
BXD43 m 2.668 4.6124   4 2.3062 1.7288 0.284, 9.586 -0.96
BXD45 m 10.588 6.4993   5 2.9066 0.6139 2.224, 17.716 -0.6
BXD48 m 13.222 24.81   5 11.095 1.8764 0.712, 57.53 -0.48
BXD48a m 24.016 26.111   4 13.056 1.0873 5.364, 62.55 0.01
BXD49 m 73.61 85.78   5 38.364 1.1654 5.35, 213.2 2.26
BXD51 m 3.1487 1.4688   3 0.848 0.4665 1.482, 4.254 -0.94
BXD53 m 24.652 19.942   5 8.9183 0.8089 7.288, 56.43 0.04
BXD55 m 42.961 41.526   5 18.571 0.9666 4.626, 96.39 0.87
BXD6 m 67.66 107.3   5 47.999 1.5864 5.4794, 257.9 1.99
BXD62 m 3.9755 2.5971   4 1.2986 0.6533 2.232, 7.834 -0.9
BXD63 m 55.61 69.8   5 31.215 1.2551 4.116, 174.1 1.44
BXD64 m 21.8 24.518   4 12.259 1.1246 4.186, 56.98 -0.09
BXD66 m 4.9519 1.8111   3 1.0456 0.3657 2.864, 6.098 -0.86
BXD67 m 51.18 38.091   5 17.035 0.7442 9.648, 94.24 1.24
BXD69 m 23.959 24.923   4 12.461 1.0402 3.952, 58.8 0.0
BXD73 m 20.053 17.499   3 10.103 0.8727 9.38, 40.248 -0.17
BXD75 m 35.735 47.79   4 23.895 1.3373 7.066, 106.7 0.54
BXD77 m 23.075 38.96   5 17.424 1.6884 1.482, 91.52 -0.04
BXD79 m 3.2432 1.3988   5 0.62554 0.4313 1.064, 4.544 -0.94
BXD8 m 70.15 96.66   2   68.35 1.3778 1.808, 138.5 2.1
BXD81 m 27.464 25.156   5 11.25 0.916 2.648, 59.62 0.16
BXD84 m 3.4452 5.263   5 2.3537 1.5276 0.366, 12.826 -0.93
BXD87 m 3.3235 3.5322   4 1.7661 1.0628 0.252, 7.67 -0.93
BXD89 m 24.623 25.623   5 11.459 1.0406 1.204, 57.63 0.03
BXD90 m 3.431 4.5525   4 2.2762 1.3269 0.226, 10.082 -0.93
C57BL/6J m 15.318 19.491   3 11.253 1.2724 3.69, 37.82 -0.39
DBA/2J m 4.122 2.7188   3 1.5697 0.6596 1.286, 6.706 -0.9


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 1.44878 19.9100197988 40.8866973609 -37.9891373609
BXD100 m 2.4986666667 18.1752782736 38.5003949327 -33.5030615993
BXD11 m 12.0393333333 25.7037250344 62.953465716 -38.8747990493
BXD12 m 8.614 25.7037250344 59.5281323827 -42.3001323827
BXD27 m 70.3824 19.9100197988 109.8203173609 30.9444826391
BXD32 m 12.8055 22.2600788517 56.898432055 -31.287432055
BXD34 m 27.444 22.2600788517 71.536932055 -16.648932055
BXD39 m 44.6573333333 25.7037250344 95.571465716 -6.2567990493
BXD40 m 21.365 22.2600788517 65.457932055 -22.727932055
BXD43 m 2.668 22.2600788517 46.760932055 -41.424932055
BXD45 m 10.5876 19.9100197988 50.0255173609 -28.8503173609
BXD48 m 13.222 19.9100197988 52.6599173609 -26.2159173609
BXD48a m 24.016 22.2600788517 68.108932055 -20.076932055
BXD49 m 73.61 19.9100197988 113.0479173609 34.1720826391
BXD51 m 3.1486666667 25.7037250344 54.0627990493 -47.765465716
BXD53 m 24.6522 19.9100197988 64.0901173609 -14.7857173609
BXD55 m 42.9612 19.9100197988 82.3991173609 3.5232826391
BXD6 m 67.65568 19.9100197988 107.0935973609 28.2177626391
BXD62 m 3.9755 22.2600788517 48.068432055 -40.117432055
BXD63 m 55.6104 19.9100197988 95.0483173609 16.1724826391
BXD64 m 21.8005 22.2600788517 65.893432055 -22.292432055
BXD66 m 4.9519 25.7037250344 55.8660323827 -45.9622323827
BXD67 m 51.1844 19.9100197988 90.6223173609 11.7464826391
BXD69 m 23.959 22.2600788517 68.051932055 -20.133932055
BXD73 m 20.0526666667 25.7037250344 70.9667990493 -30.861465716
BXD75 m 35.735 22.2600788517 79.827932055 -8.357932055
BXD77 m 23.0752 19.9100197988 62.5131173609 -16.3627173609
BXD79 m 3.2432 19.9100197988 42.6811173609 -36.1947173609
BXD8 m 70.154 31.4805054116 132.510822517 7.797177483
BXD81 m 27.4636 19.9100197988 66.9015173609 -11.9743173609
BXD84 m 3.4452 19.9100197988 42.8831173609 -35.9927173609
BXD87 m 3.3235 22.2600788517 47.416432055 -40.769432055
BXD89 m 24.6228 19.9100197988 64.0607173609 -14.8151173609
BXD90 m 3.431 22.2600788517 47.523932055 -40.661932055
C57BL/6J m 15.318 25.7037250344 66.2321323827 -35.5961323827
DBA/2J m 4.122 25.7037250344 55.0361323827 -46.7921323827




  GWAS USING LINEAR MIXED MODELS