Project measure / variable:   Auwerx1   ala_trans_CD

ID, description, units MPD:111340   ala_trans_CD   blood alanine transaminase amount   [U/L]  CD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   54 strains     sex: m     age: 29wks
Procedure metabolic panel
Ontology mappings

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  STRAIN COMPARISON PLOT
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Auwerx1 - blood alanine transaminase amount CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested54 strains
Mean of the strain means58.77   U/L
Median of the strain means50.0   U/L
SD of the strain means± 35.38
Coefficient of variation (CV)0.602
Min–max range of strain means24.333   –   196.8   U/L
Mean sample size per strain4.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 53 288155.8679 5436.9032 3.9743 < 0.0001
Residuals 171 233931.4476 1368.0202


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 49.0 38.125   5 17.05 0.7781 19.0, 115.0 -0.28
BXD100 m 24.333 3.5119   3 2.0276 0.1443 21.0, 28.0 -0.97
BXD101 m 58.5 5.1962   4 2.5981 0.0888 52.0, 64.0 -0.01
BXD12 m 36.6 15.742   5 7.0399 0.4301 22.0, 55.0 -0.63
BXD16 m 86.25 29.193   4 14.597 0.3385 60.0, 125.0 0.78
BXD27 m 44.8 7.4297   5 3.3226 0.1658 37.0, 55.0 -0.39
BXD32 m 58.2 20.681   5 9.2488 0.3553 42.0, 93.0 -0.02
BXD34 m 26.75 5.3151   4 2.6575 0.1987 20.0, 33.0 -0.91
BXD39 m 196.8 161.5   5 72.22 0.8206 29.0, 450.0 3.9
BXD40 m 51.33 7.5056   3 4.3333 0.1462 44.0, 59.0 -0.21
BXD43 m 123.3 65.52   3 37.826 0.5312 57.0, 188.0 1.82
BXD44 m 75.57 41.432   7 15.66 0.5483 29.0, 129.0 0.47
BXD45 m 29.2 4.5497   5 2.0347 0.1558 23.0, 34.0 -0.84
BXD48 m 48.8 4.2661   5 1.9079 0.0874 43.0, 55.0 -0.28
BXD48a m 28.4 7.733   5 3.4583 0.2723 21.0, 39.0 -0.86
BXD49 m 45.25 13.598   4 6.7992 0.3005 32.0, 61.0 -0.38
BXD50 m 51.0 4.0825   4 2.0412 0.08 48.0, 57.0 -0.22
BXD51 m 38.0 2.6458   3 1.5275 0.0696 36.0, 41.0 -0.59
BXD53 m 44.0 24.021   3 13.868 0.5459 25.0, 71.0 -0.42
BXD55 m 26.4 4.5607   5 2.0396 0.1728 22.0, 33.0 -0.91
BXD56 m 47.333 4.6188   3 2.6667 0.0976 42.0, 50.0 -0.32
BXD6 m 41.75 25.329   4 12.665 0.6067 19.0, 78.0 -0.48
BXD60 m 149.8 43.6   4 21.8 0.2911 108.0, 211.0 2.57
BXD61 m 31.5 0.70711   2   0.5 0.0224 31.0, 32.0 -0.77
BXD62 m 34.75 6.3966   4 3.1983 0.1841 26.0, 40.0 -0.68
BXD63 m 40.0 5.2915   3 3.0551 0.1323 34.0, 44.0 -0.53
BXD64 m 60.75 17.173   4 8.5866 0.2827 49.0, 86.0 0.06
BXD65 m 139.0 24.671   4 12.336 0.1775 104.0, 162.0 2.27
BXD65a m 93.4 20.611   5 9.2174 0.2207 72.0, 118.0 0.98
BXD65b m 118.2 39.803   4 19.901 0.3366 83.0, 172.0 1.68
BXD66 m 44.0 12.0   5 5.3666 0.2727 33.0, 57.0 -0.42
BXD67 m 55.0 33.853   4 16.926 0.6155 25.0, 90.0 -0.11
BXD68 m 73.67 7.6376   3 4.4096 0.1037 67.0, 82.0 0.42
BXD69 m 81.0 28.922   5 12.934 0.3571 62.0, 132.0 0.63
BXD70 m 27.5 6.8557   4 3.4278 0.2493 22.0, 37.0 -0.88
BXD71 m 55.75 8.7702   4 4.3851 0.1573 46.0, 67.0 -0.09
BXD73 m 32.333 6.3509   3 3.6667 0.1964 25.0, 36.0 -0.75
BXD73a m 31.2 6.261   5 2.8 0.2007 23.0, 39.0 -0.78
BXD73b m 67.4 25.813   5 11.544 0.383 49.0, 112.0 0.24
BXD75 m 26.6 3.3615   5 1.5033 0.1264 23.0, 32.0 -0.91
BXD77 m 118.8 113.9   5 50.93 0.9586 37.0, 306.0 1.7
BXD79 m 84.0 36.366   5 16.263 0.4329 54.0, 142.0 0.71
BXD81 m 53.0 10.551   4 5.2757 0.1991 43.0, 66.0 -0.16
BXD83 m 67.33 57.13   3 32.987 0.8485 29.0, 133.0 0.24
BXD84 m 52.0 1.0   3 0.57735 0.0192 51.0, 53.0 -0.19
BXD85 m 63.4 7.6026   5 3.4 0.1199 54.0, 72.0 0.13
BXD87 m 34.6 16.273   5 7.2774 0.4703 22.0, 63.0 -0.68
BXD89 m 28.25 7.8049   4 3.9025 0.2763 17.0, 35.0 -0.86
BXD90 m 30.0 2.8284   4 1.4142 0.0943 26.0, 32.0 -0.81
BXD95 m 66.0 24.752   4 12.376 0.375 51.0, 103.0 0.2
BXD98 m 76.33 26.16   3 15.103 0.3427 52.0, 104.0 0.5
BXD99 m 51.4 2.3022   5 1.0296 0.0448 49.0, 54.0 -0.21
C57BL/6J m 24.5 4.2032   4 2.1016 0.1716 20.0, 30.0 -0.97
DBA/2J m 30.5 9.4692   4 4.7346 0.3105 22.0, 44.0 -0.8


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 49.0 16.5409803912 81.6508028284 16.3491971716
BXD100 m 24.3333333333 21.3543138617 66.4853385316 -17.8186718649
BXD101 m 58.5 18.4933782846 95.0047073221 21.9952926779
BXD12 m 36.6 16.5409803912 69.2508028284 3.9491971716
BXD16 m 86.25 18.4933782846 122.7547073221 49.7452926779
BXD27 m 44.8 16.5409803912 77.4508028284 12.1491971716
BXD32 m 58.2 16.5409803912 90.8508028284 25.5491971716
BXD34 m 26.75 18.4933782846 63.2547073221 -9.7547073221
BXD39 m 196.8 16.5409803912 229.4508028284 164.1491971716
BXD40 m 51.3333333333 21.3543138617 93.4853385316 9.1813281351
BXD43 m 123.3333333333 21.3543138617 165.4853385316 81.1813281351
BXD44 m 75.5714285714 13.979679955 103.1663935022 47.9764636407
BXD45 m 29.2 16.5409803912 61.8508028284 -3.4508028284
BXD48 m 48.8 16.5409803912 81.4508028284 16.1491971716
BXD48a m 28.4 16.5409803912 61.0508028284 -4.2508028284
BXD49 m 45.25 18.4933782846 81.7547073221 8.7452926779
BXD50 m 51.0 18.4933782846 87.5047073221 14.4952926779
BXD51 m 38.0 21.3543138617 80.1520051982 -4.1520051982
BXD53 m 44.0 21.3543138617 86.1520051982 1.8479948018
BXD55 m 26.4 16.5409803912 59.0508028284 -6.2508028284
BXD56 m 47.3333333333 21.3543138617 89.4853385316 5.1813281351
BXD6 m 41.75 18.4933782846 78.2547073221 5.2452926779
BXD60 m 149.75 18.4933782846 186.2547073221 113.2452926779
BXD61 m 31.5 26.1535863842 83.1254521854 -20.1254521854
BXD62 m 34.75 18.4933782846 71.2547073221 -1.7547073221
BXD63 m 40.0 21.3543138617 82.1520051982 -2.1520051982
BXD64 m 60.75 18.4933782846 97.2547073221 24.2452926779
BXD65 m 139.0 18.4933782846 175.5047073221 102.4952926779
BXD65a m 93.4 16.5409803912 126.0508028284 60.7491971716
BXD65b m 118.25 18.4933782846 154.7547073221 81.7452926779
BXD66 m 44.0 16.5409803912 76.6508028284 11.3491971716
BXD67 m 55.0 18.4933782846 91.5047073221 18.4952926779
BXD68 m 73.6666666667 21.3543138617 115.8186718649 31.5146614684
BXD69 m 81.0 16.5409803912 113.6508028284 48.3491971716
BXD70 m 27.5 18.4933782846 64.0047073221 -9.0047073221
BXD71 m 55.75 18.4933782846 92.2547073221 19.2452926779
BXD73 m 32.3333333333 21.3543138617 74.4853385316 -9.8186718649
BXD73a m 31.2 16.5409803912 63.8508028284 -1.4508028284
BXD73b m 67.4 16.5409803912 100.0508028284 34.7491971716
BXD75 m 26.6 16.5409803912 59.2508028284 -6.0508028284
BXD77 m 118.8 16.5409803912 151.4508028284 86.1491971716
BXD79 m 84.0 16.5409803912 116.6508028284 51.3491971716
BXD81 m 53.0 18.4933782846 89.5047073221 16.4952926779
BXD83 m 67.3333333333 21.3543138617 109.4853385316 25.1813281351
BXD84 m 52.0 21.3543138617 94.1520051982 9.8479948018
BXD85 m 63.4 16.5409803912 96.0508028284 30.7491971716
BXD87 m 34.6 16.5409803912 67.2508028284 1.9491971716
BXD89 m 28.25 18.4933782846 64.7547073221 -8.2547073221
BXD90 m 30.0 18.4933782846 66.5047073221 -6.5047073221
BXD95 m 66.0 18.4933782846 102.5047073221 29.4952926779
BXD98 m 76.3333333333 21.3543138617 118.4853385316 34.1813281351
BXD99 m 51.4 16.5409803912 84.0508028284 18.7491971716
C57BL/6J m 24.5 18.4933782846 61.0047073221 -12.0047073221
DBA/2J m 30.5 18.4933782846 67.0047073221 -6.0047073221




  GWAS USING LINEAR MIXED MODELS