Project measure / variable:   Auwerx1   vo2_max_treadmill2_CD

ID, description, units MPD:111332   vo2_max_treadmill2_CD   maximum oxygen consumption, second treadmill training   [mL/kg/min]  CD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   55 strains     sex: m     age: 25wks
Procedure monitoring system
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  STRAIN COMPARISON PLOT
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Auwerx1 - maximum oxygen consumption, second treadmill training CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested55 strains
Mean of the strain means115.7   mL/kg/min
Median of the strain means116.8   mL/kg/min
SD of the strain means± 19.519
Coefficient of variation (CV)0.1687
Min–max range of strain means76.6   –   153.7   mL/kg/min
Mean sample size per strain4.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 54 86614.5499 1603.9731 12.7964 < 0.0001
Residuals 177 22186.2389 125.346


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 115.4 12.219   5 5.4644 0.1059 100.0, 127.0 -0.02
BXD100 m 117.3 22.053   3 12.732 0.188 93.0, 136.0 0.08
BXD101 m 114.5 13.204   4 6.6018 0.1153 99.0, 129.0 -0.06
BXD11 m 124.5 12.021   2   8.5 0.0966 116.0, 133.0 0.45
BXD12 m 105.2 3.7014   5 1.6553 0.0352 100.0, 109.0 -0.54
BXD16 m 80.5 6.1373   4 3.0687 0.0762 73.0, 88.0 -1.8
BXD2 m 90.25 7.6322   4 3.8161 0.0846 81.0, 99.0 -1.31
BXD27 m 108.6 16.727   5 7.4806 0.154 84.0, 127.0 -0.36
BXD32 m 142.6 15.356   5 6.8673 0.1077 128.0, 160.0 1.38
BXD34 m 107.8 12.606   4 6.3031 0.117 96.0, 121.0 -0.41
BXD39 m 88.0 3.873   5 1.7321 0.044 83.0, 92.0 -1.42
BXD40 m 134.7 14.572   3 8.413 0.1082 121.0, 150.0 0.97
BXD43 m 128.3 8.3267   3 4.8074 0.0649 119.0, 135.0 0.64
BXD44 m 119.4 15.076   9 5.0252 0.1262 105.0, 153.0 0.19
BXD45 m 138.5 3.873   4 1.9365 0.028 133.0, 142.0 1.17
BXD48 m 79.0 16.508   5 7.3824 0.209 66.0, 99.0 -1.88
BXD48a m 104.2 15.019   4 7.5097 0.1441 82.0, 115.0 -0.59
BXD49 m 93.0 5.2281   4 2.6141 0.0562 89.0, 100.0 -1.16
BXD50 m 98.0 4.5461   4 2.273 0.0464 93.0, 104.0 -0.91
BXD51 m 143.5 1.9149   4 0.95743 0.0133 141.0, 145.0 1.42
BXD53 m 117.0 16.897   5 7.5565 0.1444 102.0, 141.0 0.07
BXD55 m 141.0 8.6313   5 3.8601 0.0612 133.0, 155.0 1.3
BXD56 m 124.0 14.0   3 8.0829 0.1129 108.0, 134.0 0.42
BXD6 m 114.2 9.7314   5 4.352 0.0852 105.0, 127.0 -0.08
BXD60 m 85.8 11.777   5 5.2669 0.1373 75.0, 106.0 -1.53
BXD61 m 148.0 3.6056   3 2.0817 0.0244 145.0, 152.0 1.65
BXD62 m 115.0 6.6833   4 3.3417 0.0581 109.0, 124.0 -0.04
BXD63 m 110.0 20.412   4 10.206 0.1856 90.0, 130.0 -0.29
BXD64 m 104.5 5.1962   4 2.5981 0.0497 99.0, 111.0 -0.57
BXD65 m 85.0 6.9761   4 3.4881 0.0821 79.0, 95.0 -1.57
BXD65a m 98.6 13.05   5 5.8361 0.1324 77.0, 112.0 -0.88
BXD65b m 88.0 8.9815   4 4.4907 0.1021 78.0, 97.0 -1.42
BXD66 m 76.6 7.9561   5 3.5581 0.1039 65.0, 85.0 -2.0
BXD67 m 101.0 10.886   5 4.8683 0.1078 88.0, 113.0 -0.75
BXD68 m 121.3 8.5049   3 4.9103 0.0701 113.0, 130.0 0.29
BXD69 m 103.6 4.827   5 2.1587 0.0466 98.0, 111.0 -0.62
BXD70 m 126.8 14.175   4 7.0873 0.1118 112.0, 146.0 0.57
BXD73 m 129.2 13.598   4 6.7992 0.1052 112.0, 142.0 0.69
BXD73a m 110.0 7.3937   4 3.6968 0.0672 101.0, 119.0 -0.29
BXD73b m 101.3 14.468   3 8.3533 0.1428 92.0, 118.0 -0.74
BXD75 m 133.6 13.05   5 5.8361 0.0977 114.0, 146.0 0.92
BXD77 m 126.4 13.759   5 6.153 0.1088 109.0, 146.0 0.55
BXD79 m 92.8 7.5631   5 3.3823 0.0815 85.0, 105.0 -1.17
BXD8 m 131.8 6.2383   4 3.1192 0.0473 125.0, 138.0 0.82
BXD81 m 116.8 10.046   4 5.0229 0.086 104.0, 128.0 0.06
BXD83 m 131.7 4.7258   3 2.7285 0.0359 128.0, 137.0 0.82
BXD84 m 139.8 7.2284   4 3.6142 0.0517 134.0, 149.0 1.23
BXD87 m 138.2 4.717   4 2.3585 0.0341 135.0, 145.0 1.15
BXD89 m 132.5 9.1104   4 4.5552 0.0688 120.0, 141.0 0.86
BXD90 m 127.0 14.81   4 7.405 0.1166 111.0, 144.0 0.58
BXD95 m 117.8 13.074   4 6.5368 0.111 102.0, 129.0 0.11
BXD98 m 111.5 3.873   4 1.9365 0.0347 108.0, 117.0 -0.22
BXD99 m 138.8 6.5727   5 2.9394 0.0474 131.0, 147.0 1.18
C57BL/6J m 138.2 9.4296   4 4.7148 0.0682 125.0, 147.0 1.15
DBA/2J m 153.7 13.577   3 7.8387 0.0884 141.0, 168.0 1.95


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 115.4 5.0069148669 125.2809322019 105.5190677981
BXD100 m 117.3333333333 6.4638992985 130.0895619543 104.5771047123
BXD101 m 114.5 5.597901 125.5472180423 103.4527819577
BXD11 m 124.5 7.916627515 140.1231255818 108.8768744182
BXD12 m 105.2 5.0069148669 115.0809322019 95.3190677981
BXD16 m 80.5 5.597901 91.5472180423 69.4527819577
BXD2 m 90.25 5.597901 101.2972180423 79.2027819577
BXD27 m 108.6 5.0069148669 118.4809322019 98.7190677981
BXD32 m 142.6 5.0069148669 152.4809322019 132.7190677981
BXD34 m 107.75 5.597901 118.7972180423 96.7027819577
BXD39 m 88.0 5.0069148669 97.8809322019 78.1190677981
BXD40 m 134.6666666667 6.4638992985 147.4228952877 121.9104380457
BXD43 m 128.3333333333 6.4638992985 141.0895619543 115.5771047123
BXD44 m 119.4444444444 3.731934 126.8092564726 112.0796324163
BXD45 m 138.5 5.597901 149.5472180423 127.4527819577
BXD48 m 79.0 5.0069148669 88.8809322019 69.1190677981
BXD48a m 104.25 5.597901 115.2972180423 93.2027819577
BXD49 m 93.0 5.597901 104.0472180423 81.9527819577
BXD50 m 98.0 5.597901 109.0472180423 86.9527819577
BXD51 m 143.5 5.597901 154.5472180423 132.4527819577
BXD53 m 117.0 5.0069148669 126.8809322019 107.1190677981
BXD55 m 141.0 5.0069148669 150.8809322019 131.1190677981
BXD56 m 124.0 6.4638992985 136.756228621 111.243771379
BXD6 m 114.2 5.0069148669 124.0809322019 104.3190677981
BXD60 m 85.8 5.0069148669 95.6809322019 75.9190677981
BXD61 m 148.0 6.4638992985 160.756228621 135.243771379
BXD62 m 115.0 5.597901 126.0472180423 103.9527819577
BXD63 m 110.0 5.597901 121.0472180423 98.9527819577
BXD64 m 104.5 5.597901 115.5472180423 93.4527819577
BXD65 m 85.0 5.597901 96.0472180423 73.9527819577
BXD65a m 98.6 5.0069148669 108.4809322019 88.7190677981
BXD65b m 88.0 5.597901 99.0472180423 76.9527819577
BXD66 m 76.6 5.0069148669 86.4809322019 66.7190677981
BXD67 m 101.0 5.0069148669 110.8809322019 91.1190677981
BXD68 m 121.3333333333 6.4638992985 134.0895619543 108.5771047123
BXD69 m 103.6 5.0069148669 113.4809322019 93.7190677981
BXD70 m 126.75 5.597901 137.7972180423 115.7027819577
BXD73 m 129.25 5.597901 140.2972180423 118.2027819577
BXD73a m 110.0 5.597901 121.0472180423 98.9527819577
BXD73b m 101.3333333333 6.4638992985 114.0895619543 88.5771047123
BXD75 m 133.6 5.0069148669 143.4809322019 123.7190677981
BXD77 m 126.4 5.0069148669 136.2809322019 116.5190677981
BXD79 m 92.8 5.0069148669 102.6809322019 82.9190677981
BXD8 m 131.75 5.597901 142.7972180423 120.7027819577
BXD81 m 116.75 5.597901 127.7972180423 105.7027819577
BXD83 m 131.6666666667 6.4638992985 144.4228952877 118.9104380457
BXD84 m 139.75 5.597901 150.7972180423 128.7027819577
BXD87 m 138.25 5.597901 149.2972180423 127.2027819577
BXD89 m 132.5 5.597901 143.5472180423 121.4527819577
BXD90 m 127.0 5.597901 138.0472180423 115.9527819577
BXD95 m 117.75 5.597901 128.7972180423 106.7027819577
BXD98 m 111.5 5.597901 122.5472180423 100.4527819577
BXD99 m 138.8 5.0069148669 148.6809322019 128.9190677981
C57BL/6J m 138.25 5.597901 149.2972180423 127.2027819577
DBA/2J m 153.6666666667 6.4638992985 166.4228952877 140.9104380457




  GWAS USING LINEAR MIXED MODELS