Project measure / variable:   Auwerx1   dist_wheel_HFD

ID, description, units MPD:111321   dist_wheel_HFD   distance traveled, voluntary wheel running test, last 24h   [km]  HFD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   56 strains     sex: m     age: 23wks
Procedure running wheel monitoring
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  STRAIN COMPARISON PLOT
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Auwerx1 - distance traveled, voluntary wheel running test, last 24h HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested56 strains
Mean of the strain means2.9345   km
Median of the strain means2.2359   km
SD of the strain means± 2.41
Coefficient of variation (CV)0.8213
Min–max range of strain means0.0742   –   8.478   km
Mean sample size per strain4.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 55 1387.024 25.2186 6.7849 < 0.0001
Residuals 186 691.3418 3.7169


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 1.488 0.61416   5 0.27466 0.4127 0.753, 2.1 -0.6
BXD100 m 5.91 4.3329   5 1.9377 0.7331 1.34, 12.83 1.23
BXD101 m 4.8 4.407   4 2.2035 0.9181 0.85, 10.7 0.77
BXD11 m 0.35635 0.50486   4 0.25243 1.4167 0.01915, 1.0905 -1.07
BXD12 m 0.59478 0.56835   5 0.25417 0.9556 0.0030709, 1.2027 -0.97
BXD16 m 0.296 0.18434   5 0.08244 0.6228 0.1, 0.548 -1.09
BXD2 m 2.1588 1.9425   5 0.86872 0.8998 0.464, 5.51 -0.32
BXD27 m 4.79 1.3737   4 0.68684 0.2868 3.56, 6.65 0.77
BXD32 m 1.0673 0.49078   3 0.28335 0.4598 0.514, 1.45 -0.77
BXD34 m 4.0925 1.1287   4 0.56433 0.2758 3.43, 5.78 0.48
BXD39 m 1.128 1.133   5 0.50669 1.0044 0.37, 3.1 -0.75
BXD40 m 7.35 3.3524   4 1.6762 0.4561 4.11, 11.29 1.83
BXD43 m 7.84 1.1435   3 0.66018 0.1458 6.99, 9.14 2.04
BXD44 m 0.40412 0.61643   9 0.20548 1.5253 0.07, 2.0326 -1.05
BXD45 m 6.9276 0.64573   4 0.32287 0.0932 6.4211, 7.8704 1.66
BXD48 m 2.417 1.5901   5 0.71111 0.6579 0.9014, 4.7171 -0.21
BXD48a m 1.03 0.34176   3 0.19732 0.3318 0.67, 1.35 -0.79
BXD49 m 0.3431 0.25208   5 0.11273 0.7347 0.0414, 0.6682 -1.08
BXD50 m 1.8763 0.72111   5 0.32249 0.3843 0.7815, 2.6717 -0.44
BXD51 m 1.3704 1.3962   4 0.6981 1.0188 0.1053, 3.1428 -0.65
BXD53 m 2.17 0.91796   5 0.41052 0.423 1.27, 3.21 -0.32
BXD55 m 7.4351 0.85199   4 0.426 0.1146 6.7023, 8.664 1.87
BXD56 m 1.434 0.6686   3 0.38601 0.4662 1.014, 2.205 -0.62
BXD6 m 1.127 0.36741   5 0.16431 0.326 0.678, 1.55 -0.75
BXD60 m 0.3758 0.21816   5 0.09757 0.5805 0.18, 0.745 -1.06
BXD61 m 1.74 0.90449   5 0.4045 0.5198 0.75, 2.63 -0.5
BXD62 m 0.4345 0.27571   4 0.13785 0.6345 0.098, 0.66 -1.04
BXD63 m 2.525 1.591   2   1.125 0.6301 1.4, 3.65 -0.17
BXD64 m 3.1638 3.2387   4 1.6194 1.0237 0.594, 7.48 0.1
BXD65 m 0.661 0.19789   4 0.09895 0.2994 0.432, 0.865 -0.94
BXD65a m 0.47875 0.13143   4 0.06571 0.2745 0.36, 0.655 -1.02
BXD66 m 0.0742 0.07901   5 0.03534 1.0649 0.001, 0.2 -1.19
BXD67 m 0.9034 0.8779   5 0.39261 0.9718 0.218, 2.23 -0.84
BXD68 m 7.9363 4.6555   4 2.3278 0.5866 1.248, 11.905 2.08
BXD69 m 2.4138 2.0301   5 0.90789 0.841 0.121, 4.456 -0.22
BXD70 m 6.5675 1.0209   4 0.51046 0.1554 5.3497, 7.6955 1.51
BXD71 m 2.2518 2.0918   3 1.2077 0.9289 0.3, 4.46 -0.28
BXD73 m 2.4031 1.549   3 0.89433 0.6446 0.7215, 3.7718 -0.22
BXD73a m 1.0567 0.48676   3 0.28103 0.4607 0.53, 1.49 -0.78
BXD73b m 2.22 1.3831   4 0.69157 0.623 1.32, 4.28 -0.3
BXD75 m 4.504 3.6976   5 1.6536 0.821 2.3, 11.01 0.65
BXD77 m 4.0694 3.2002   5 1.4312 0.7864 0.437, 7.89 0.47
BXD79 m 0.3472 0.19104   5 0.08544 0.5502 0.1, 0.574 -1.07
BXD8 m 5.332 1.546   5 0.6914 0.29 3.75, 7.6 0.99
BXD81 m 3.2298 2.7413   4 1.3706 0.8488 0.087, 6.065 0.12
BXD83 m 2.31 1.7232   4 0.86158 0.746 0.71, 4.08 -0.26
BXD84 m 5.4 5.3627   3 3.0961 0.9931 0.64, 11.21 1.02
BXD85 m 1.2242 0.97409   4 0.48704 0.7957 0.495, 2.66 -0.71
BXD87 m 1.0567 0.48676   3 0.28103 0.4607 0.53, 1.49 -0.78
BXD89 m 5.2025 0.70858   4 0.35429 0.1362 4.18, 5.69 0.94
BXD90 m 3.1412 3.5302   4 1.7651 1.1238 0.005, 6.5 0.09
BXD95 m 3.4177 3.3531   5 1.4995 0.9811 0.029, 7.95 0.2
BXD98 m 1.746 0.37173   5 0.16624 0.2129 1.32, 2.16 -0.49
BXD99 m 7.1864 1.9604   5 0.87671 0.2728 4.704, 9.685 1.76
C57BL/6J m 4.0725 1.2958   4 0.64792 0.3182 2.61, 5.51 0.47
DBA/2J m 8.478 1.5901   5 0.71109 0.1876 7.23, 10.93 2.3


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 1.488 0.8621938835 3.1889361916 -0.2129361916
BXD100 m 5.91 0.8621938835 7.6109361916 4.2090638084
BXD101 m 4.8 0.9639620666 6.7017044749 2.8982955251
BXD11 m 0.3563525 0.9639620666 2.2580569749 -1.5453519749
BXD12 m 0.59478164 0.8621938835 2.2957178316 -1.1061545516
BXD16 m 0.296 0.8621938835 1.9969361916 -1.4049361916
BXD2 m 2.1588 0.8621938835 3.8597361916 0.4578638084
BXD27 m 4.79 0.9639620666 6.6917044749 2.8882955251
BXD32 m 1.0673333333 1.1130875173 3.2632325143 -1.1285658477
BXD34 m 4.0925 0.9639620666 5.9942044749 2.1907955251
BXD39 m 1.128 0.8621938835 2.8289361916 -0.5729361916
BXD40 m 7.35 0.9639620666 9.2517044749 5.4482955251
BXD43 m 7.84 1.1130875173 10.035899181 5.644100819
BXD44 m 0.4041222222 0.6426413777 1.6719252055 -0.863680761
BXD45 m 6.927625 0.9639620666 8.8293294749 5.0259205251
BXD48 m 2.41702 0.8621938835 4.1179561916 0.7160838084
BXD48a m 1.03 1.1130875173 3.225899181 -1.165899181
BXD49 m 0.343096 0.8621938835 2.0440321916 -1.3578401916
BXD50 m 1.87626 0.8621938835 3.5771961916 0.1753238084
BXD51 m 1.370375 0.9639620666 3.2720794749 -0.5313294749
BXD53 m 2.17 0.8621938835 3.8709361916 0.4690638084
BXD55 m 7.435075 0.9639620666 9.3367794749 5.5333705251
BXD56 m 1.434 1.1130875173 3.629899181 -0.761899181
BXD6 m 1.127 0.8621938835 2.8279361916 -0.5739361916
BXD60 m 0.3758 0.8621938835 2.0767361916 -1.3251361916
BXD61 m 1.74 0.8621938835 3.4409361916 0.0390638084
BXD62 m 0.4345 0.9639620666 2.3362044749 -1.4672044749
BXD63 m 2.525 1.3632482282 5.21441626 -0.16441626
BXD64 m 3.16375 0.9639620666 5.0654544749 1.2620455251
BXD65 m 0.661 0.9639620666 2.5627044749 -1.2407044749
BXD65a m 0.47875 0.9639620666 2.3804544749 -1.4229544749
BXD66 m 0.0742 0.8621938835 1.7751361916 -1.6267361916
BXD67 m 0.9034 0.8621938835 2.6043361916 -0.7975361916
BXD68 m 7.93625 0.9639620666 9.8379544749 6.0345455251
BXD69 m 2.4138 0.8621938835 4.1147361916 0.7128638084
BXD70 m 6.567525 0.9639620666 8.4692294749 4.6658205251
BXD71 m 2.2518333333 1.1130875173 4.4477325143 0.0559341523
BXD73 m 2.4030666667 1.1130875173 4.5989658477 0.2071674857
BXD73a m 1.0566666667 1.1130875173 3.2525658477 -1.1392325143
BXD73b m 2.22 0.9639620666 4.1217044749 0.3182955251
BXD75 m 4.504 0.8621938835 6.2049361916 2.8030638084
BXD77 m 4.0694 0.8621938835 5.7703361916 2.3684638084
BXD79 m 0.3472 0.8621938835 2.0481361916 -1.3537361916
BXD8 m 5.332 0.8621938835 7.0329361916 3.6310638084
BXD81 m 3.22975 0.9639620666 5.1314544749 1.3280455251
BXD83 m 2.31 0.9639620666 4.2117044749 0.4082955251
BXD84 m 5.4 1.1130875173 7.595899181 3.204100819
BXD85 m 1.22415 0.9639620666 3.1258544749 -0.6775544749
BXD87 m 1.0566666667 1.1130875173 3.2525658477 -1.1392325143
BXD89 m 5.2025 0.9639620666 7.1042044749 3.3007955251
BXD90 m 3.14125 0.9639620666 5.0429544749 1.2395455251
BXD95 m 3.41774 0.8621938835 5.1186761916 1.7168038084
BXD98 m 1.746 0.8621938835 3.4469361916 0.0450638084
BXD99 m 7.1864 0.8621938835 8.8873361916 5.4854638084
C57BL/6J m 4.0725 0.9639620666 5.9742044749 2.1707955251
DBA/2J m 8.478 0.8621938835 10.1789361916 6.7770638084




  GWAS USING LINEAR MIXED MODELS