Project measure / variable:   Auwerx1   ogtt_gluc_t150_HFD

ID, description, units MPD:111259   ogtt_gluc_t150_HFD   glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 150 min   [mg/dL]  HFD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   56 strains     sex: m     age: 17wks
Procedure glucose tolerance
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  STRAIN COMPARISON PLOT
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Auwerx1 - glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 150 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested56 strains
Mean of the strain means227.2   mg/dL
Median of the strain means193.8   mg/dL
SD of the strain means± 93.65
Coefficient of variation (CV)0.4122
Min–max range of strain means123.6   –   489.2   mg/dL
Mean sample size per strain4.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 55 2080950.2379 37835.4589 17.5266 < 0.0001
Residuals 187 403684.7333 2158.7419


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 133.6 54.34   5 24.303 0.4068 60.0, 203.0 -1.0
BXD100 m 176.6 46.544   5 20.815 0.2636 117.0, 237.0 -0.54
BXD101 m 170.2 5.6199   4 2.81 0.033 163.0, 176.0 -0.61
BXD11 m 165.4 41.374   5 18.503 0.2501 132.0, 234.0 -0.66
BXD12 m 123.6 22.3   5 9.973 0.1804 106.0, 162.0 -1.11
BXD16 m 181.4 35.585   5 15.914 0.1962 129.0, 215.0 -0.49
BXD2 m 150.0 32.288   5 14.44 0.2153 107.0, 188.0 -0.82
BXD27 m 236.0 49.659   4 24.829 0.2104 176.0, 291.0 0.09
BXD32 m 175.3 61.23   3 35.352 0.3492 138.0, 246.0 -0.55
BXD34 m 139.2 33.462   5 14.965 0.2404 102.0, 182.0 -0.94
BXD39 m 420.2 56.75   5 25.38 0.1351 352.0, 485.0 2.06
BXD40 m 132.8 19.956   4 9.9781 0.1503 110.0, 150.0 -1.01
BXD43 m 190.0 25.942   3 14.978 0.1365 161.0, 211.0 -0.4
BXD44 m 459.5 46.837   4 23.418 0.1019 422.0, 520.0 2.48
BXD45 m 182.0 16.912   4 8.4558 0.0929 162.0, 197.0 -0.48
BXD48 m 205.5 44.426   4 22.213 0.2162 140.0, 237.0 -0.23
BXD48a m 276.7 75.8   3 43.762 0.274 208.0, 358.0 0.53
BXD49 m 171.5 46.033   4 23.016 0.2684 127.0, 233.0 -0.59
BXD50 m 161.8 13.349   5 5.9699 0.0825 140.0, 172.0 -0.7
BXD51 m 191.2 16.378   4 8.1892 0.0856 170.0, 209.0 -0.38
BXD53 m 201.6 39.74   5 17.772 0.1971 159.0, 254.0 -0.27
BXD55 m 133.0 16.391   4 8.1955 0.1232 120.0, 157.0 -1.01
BXD56 m 219.5 47.753   4 23.876 0.2176 177.0, 268.0 -0.08
BXD6 m 134.4 8.8487   5 3.9573 0.0658 120.0, 143.0 -0.99
BXD60 m 206.0 16.093   5 7.1972 0.0781 193.0, 233.0 -0.23
BXD61 m 180.2 34.076   5 15.239 0.1891 148.0, 223.0 -0.5
BXD62 m 212.8 79.82   4 39.911 0.3752 153.0, 328.0 -0.15
BXD63 m 364.8 72.15   4 36.073 0.1978 263.0, 430.0 1.47
BXD64 m 390.5 63.11   4 31.553 0.1616 304.0, 444.0 1.74
BXD65 m 247.8 46.985   4 23.492 0.1896 179.0, 285.0 0.22
BXD65a m 221.5 68.16   4 34.082 0.3077 161.0, 291.0 -0.06
BXD66 m 147.0 7.7028   4 3.8514 0.0524 140.0, 157.0 -0.86
BXD67 m 207.2 19.588   5 8.7601 0.0945 188.0, 235.0 -0.21
BXD68 m 162.0 45.336   4 22.668 0.2799 106.0, 212.0 -0.7
BXD69 m 404.4 48.829   5 21.837 0.1207 340.0, 465.0 1.89
BXD70 m 145.0 39.455   4 19.727 0.2721 111.0, 188.0 -0.88
BXD71 m 384.3 113.4   3 65.47 0.295 256.0, 471.0 1.68
BXD73 m 190.6 32.723   5 14.634 0.1717 158.0, 231.0 -0.39
BXD73a m 176.0 12.111   4 6.0553 0.0688 158.0, 184.0 -0.55
BXD73b m 208.4 28.005   5 12.524 0.1344 176.0, 246.0 -0.2
BXD75 m 180.4 53.56   5 23.953 0.2969 130.0, 264.0 -0.5
BXD77 m 228.8 45.626   5 20.404 0.1994 167.0, 293.0 0.02
BXD79 m 333.8 99.03   5 44.287 0.2967 179.0, 429.0 1.14
BXD8 m 156.6 27.835   5 12.448 0.1777 125.0, 201.0 -0.75
BXD81 m 303.2 45.331   4 22.666 0.1495 257.0, 363.0 0.81
BXD83 m 210.5 47.078   4 23.539 0.2236 169.0, 273.0 -0.18
BXD84 m 416.3 51.33   3 29.633 0.1233 359.0, 458.0 2.02
BXD85 m 392.0 74.7   4 37.35 0.1906 315.0, 459.0 1.76
BXD87 m 192.2 45.207   5 20.217 0.2352 170.0, 273.0 -0.37
BXD89 m 141.2 44.44   4 22.22 0.3146 85.0, 191.0 -0.92
BXD90 m 157.5 20.29   4 10.145 0.1288 138.0, 186.0 -0.74
BXD95 m 234.0 38.308   5 17.132 0.1637 197.0, 289.0 0.07
BXD98 m 489.2 53.4   5 23.882 0.1092 424.0, 561.0 2.8
BXD99 m 285.8 72.69   5 32.506 0.2543 176.0, 370.0 0.63
C57BL/6J m 227.5 22.219   4 11.109 0.0977 205.0, 258.0 0.0
DBA/2J m 195.3 35.218   3 20.333 0.1803 175.0, 236.0 -0.34


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 133.6 20.7785557221 174.5905017024 92.6094982976
BXD100 m 176.6 20.7785557221 217.5905017024 135.6094982976
BXD101 m 170.25 23.2311315344 216.0787741192 124.4212258808
BXD11 m 165.4 20.7785557221 206.3905017024 124.4094982976
BXD12 m 123.6 20.7785557221 164.5905017024 82.6094982976
BXD16 m 181.4 20.7785557221 222.3905017024 140.4094982976
BXD2 m 150.0 20.7785557221 190.9905017024 109.0094982976
BXD27 m 236.0 23.2311315344 281.8287741192 190.1712258808
BXD32 m 175.3333333333 26.82500009 228.251843482 122.4148231846
BXD34 m 139.2 20.7785557221 180.1905017024 98.2094982976
BXD39 m 420.2 20.7785557221 461.1905017024 379.2094982976
BXD40 m 132.75 23.2311315344 178.5787741192 86.9212258808
BXD43 m 190.0 26.82500009 242.9185101487 137.0814898513
BXD44 m 459.5 23.2311315344 505.3287741192 413.6712258808
BXD45 m 182.0 23.2311315344 227.8287741192 136.1712258808
BXD48 m 205.5 23.2311315344 251.3287741192 159.6712258808
BXD48a m 276.6666666667 26.82500009 329.5851768154 223.748156518
BXD49 m 171.5 23.2311315344 217.3287741192 125.6712258808
BXD50 m 161.8 20.7785557221 202.7905017024 120.8094982976
BXD51 m 191.25 23.2311315344 237.0787741192 145.4212258808
BXD53 m 201.6 20.7785557221 242.5905017024 160.6094982976
BXD55 m 133.0 23.2311315344 178.8287741192 87.1712258808
BXD56 m 219.5 23.2311315344 265.3287741192 173.6712258808
BXD6 m 134.4 20.7785557221 175.3905017024 93.4094982976
BXD60 m 206.0 20.7785557221 246.9905017024 165.0094982976
BXD61 m 180.2 20.7785557221 221.1905017024 139.2094982976
BXD62 m 212.75 23.2311315344 258.5787741192 166.9212258808
BXD63 m 364.75 23.2311315344 410.5787741192 318.9212258808
BXD64 m 390.5 23.2311315344 436.3287741192 344.6712258808
BXD65 m 247.75 23.2311315344 293.5787741192 201.9212258808
BXD65a m 221.5 23.2311315344 267.3287741192 175.6712258808
BXD66 m 147.0 23.2311315344 192.8287741192 101.1712258808
BXD67 m 207.2 20.7785557221 248.1905017024 166.2094982976
BXD68 m 162.0 23.2311315344 207.8287741192 116.1712258808
BXD69 m 404.4 20.7785557221 445.3905017024 363.4094982976
BXD70 m 145.0 23.2311315344 190.8287741192 99.1712258808
BXD71 m 384.3333333333 26.82500009 437.251843482 331.4148231846
BXD73 m 190.6 20.7785557221 231.5905017024 149.6094982976
BXD73a m 176.0 23.2311315344 221.8287741192 130.1712258808
BXD73b m 208.4 20.7785557221 249.3905017024 167.4094982976
BXD75 m 180.4 20.7785557221 221.3905017024 139.4094982976
BXD77 m 228.8 20.7785557221 269.7905017024 187.8094982976
BXD79 m 333.8 20.7785557221 374.7905017024 292.8094982976
BXD8 m 156.6 20.7785557221 197.5905017024 115.6094982976
BXD81 m 303.25 23.2311315344 349.0787741192 257.4212258808
BXD83 m 210.5 23.2311315344 256.3287741192 164.6712258808
BXD84 m 416.3333333333 26.82500009 469.251843482 363.4148231846
BXD85 m 392.0 23.2311315344 437.8287741192 346.1712258808
BXD87 m 192.2 20.7785557221 233.1905017024 151.2094982976
BXD89 m 141.25 23.2311315344 187.0787741192 95.4212258808
BXD90 m 157.5 23.2311315344 203.3287741192 111.6712258808
BXD95 m 234.0 20.7785557221 274.9905017024 193.0094982976
BXD98 m 489.2 20.7785557221 530.1905017024 448.2094982976
BXD99 m 285.8 20.7785557221 326.7905017024 244.8094982976
C57BL/6J m 227.5 23.2311315344 273.3287741192 181.6712258808
DBA/2J m 195.3333333333 26.82500009 248.251843482 142.4148231846




  GWAS USING LINEAR MIXED MODELS