Project measure / variable:   Auwerx1   ogtt_gluc_t150_CD

ID, description, units MPD:111258   ogtt_gluc_t150_CD   glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 150 min   [mg/dL]  CD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   57 strains     sex: m     age: 17wks
Procedure glucose tolerance
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  STRAIN COMPARISON PLOT
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Auwerx1 - glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 150 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested57 strains
Mean of the strain means145.2   mg/dL
Median of the strain means130.0   mg/dL
SD of the strain means± 50.2
Coefficient of variation (CV)0.3457
Min–max range of strain means83.5   –   360.0   mg/dL
Mean sample size per strain4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 56 646940.8651 11552.5154 12.5111 < 0.0001
Residuals 194 179135.35 923.3781


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 107.4 11.589   5 5.1827 0.1079 97.0, 126.0 -0.75
BXD100 m 157.7 26.083   3 15.059 0.1654 128.0, 177.0 0.25
BXD101 m 133.2 7.6322   4 3.8161 0.0573 122.0, 139.0 -0.24
BXD11 m 118.5 39.162   4 19.581 0.3305 79.0, 171.0 -0.53
BXD12 m 110.2 8.1056   5 3.6249 0.0736 100.0, 117.0 -0.7
BXD16 m 159.2 30.729   4 15.364 0.193 115.0, 185.0 0.28
BXD2 m 122.0 6.7823   4 3.3912 0.0556 112.0, 127.0 -0.46
BXD27 m 145.4 19.191   5 8.5825 0.132 126.0, 175.0 0.0
BXD32 m 101.0 13.172   5 5.8907 0.1304 85.0, 121.0 -0.88
BXD34 m 150.8 24.35   4 12.175 0.1615 118.0, 176.0 0.11
BXD39 m 225.2 22.993   5 10.283 0.1021 186.0, 244.0 1.59
BXD40 m 111.0 2.9439   4 1.472 0.0265 108.0, 114.0 -0.68
BXD43 m 144.5 16.941   4 8.4705 0.1172 120.0, 158.0 -0.01
BXD44 m 315.0 65.38   4 32.688 0.2075 234.0, 394.0 3.38
BXD45 m 142.0 2.4495   4 1.2247 0.0172 139.0, 145.0 -0.06
BXD48 m 125.2 18.679   4 9.3397 0.1491 108.0, 146.0 -0.4
BXD48a m 158.6 21.582   5 9.6519 0.1361 132.0, 180.0 0.27
BXD49 m 130.0 7.874   4 3.937 0.0606 119.0, 137.0 -0.3
BXD50 m 156.8 26.887   4 13.444 0.1715 124.0, 185.0 0.23
BXD51 m 125.2 12.633   4 6.3163 0.1009 107.0, 136.0 -0.4
BXD53 m 95.0 22.804   5 10.198 0.24 69.0, 117.0 -1.0
BXD55 m 108.4 14.519   5 6.4931 0.1339 93.0, 129.0 -0.73
BXD56 m 139.0 22.528   5 10.075 0.1621 112.0, 163.0 -0.12
BXD6 m 120.4 14.69   5 6.5696 0.122 107.0, 143.0 -0.49
BXD60 m 119.6 28.139   5 12.584 0.2353 75.0, 153.0 -0.51
BXD61 m 108.7 6.3509   3 3.6667 0.0584 105.0, 116.0 -0.73
BXD62 m 127.2 21.14   4 10.57 0.1661 107.0, 157.0 -0.36
BXD63 m 187.0 15.636   5 6.9929 0.0836 167.0, 205.0 0.83
BXD64 m 180.2 114.7   4 57.35 0.6364 108.0, 350.0 0.7
BXD65 m 181.2 15.13   4 7.565 0.0835 167.0, 202.0 0.72
BXD65a m 218.8 82.06   5 36.698 0.375 161.0, 360.0 1.47
BXD65b m 194.8 23.143   4 11.571 0.1188 178.0, 229.0 0.99
BXD66 m 118.0 13.441   4 6.7206 0.1139 106.0, 132.0 -0.54
BXD67 m 116.8 14.342   5 6.414 0.1228 102.0, 133.0 -0.57
BXD68 m 141.2 37.745   5 16.88 0.2673 104.0, 186.0 -0.08
BXD69 m 360.0 77.17   5 34.512 0.2144 269.0, 469.0 4.28
BXD70 m 87.25 15.65   4 7.8249 0.1794 64.0, 97.0 -1.15
BXD71 m 144.6 17.009   5 7.6066 0.1176 119.0, 159.0 -0.01
BXD73 m 157.0 14.283   4 7.1414 0.091 148.0, 178.0 0.23
BXD73a m 136.8 17.037   4 8.5184 0.1246 122.0, 152.0 -0.17
BXD73b m 168.2 29.945   5 13.392 0.178 128.0, 204.0 0.46
BXD75 m 118.0 16.386   5 7.328 0.1389 98.0, 143.0 -0.54
BXD77 m 129.6 13.686   5 6.1205 0.1056 118.0, 153.0 -0.31
BXD79 m 156.8 15.057   5 6.7335 0.096 140.0, 180.0 0.23
BXD8 m 100.0 28.717   4 14.359 0.2872 60.0, 128.0 -0.9
BXD81 m 104.0 11.916   4 5.9582 0.1146 89.0, 115.0 -0.82
BXD83 m 128.3 10.693   3 6.1734 0.0833 119.0, 140.0 -0.34
BXD84 m 187.8 7.1903   5 3.2156 0.0383 178.0, 197.0 0.85
BXD85 m 236.2 55.18   5 24.679 0.2336 177.0, 305.0 1.81
BXD87 m 114.8 7.8867   5 3.527 0.0687 103.0, 123.0 -0.61
BXD89 m 83.5 15.801   4 7.9004 0.1892 69.0, 106.0 -1.23
BXD90 m 101.5 15.155   4 7.5774 0.1493 82.0, 118.0 -0.87
BXD95 m 148.0 27.653   4 13.826 0.1868 123.0, 187.0 0.06
BXD98 m 176.2 20.017   5 8.9521 0.1136 159.0, 208.0 0.62
BXD99 m 126.6 15.821   5 7.0753 0.125 112.0, 152.0 -0.37
C57BL/6J m 122.8 11.325   4 5.6624 0.0923 107.0, 134.0 -0.45
DBA/2J m 95.0 13.54   4 6.77 0.1425 76.0, 108.0 -1.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 107.4 13.589540778 134.2022100591 80.5977899409
BXD100 m 157.6666666667 17.5440217053 192.2681710669 123.0651622665
BXD101 m 133.25 15.1935684813 163.2157818197 103.2842181803
BXD11 m 118.5 15.1935684813 148.4657818197 88.5342181803
BXD12 m 110.2 13.589540778 137.0022100591 83.3977899409
BXD16 m 159.25 15.1935684813 189.2157818197 129.2842181803
BXD2 m 122.0 15.1935684813 151.9657818197 92.0342181803
BXD27 m 145.4 13.589540778 172.2022100591 118.5977899409
BXD32 m 101.0 13.589540778 127.8022100591 74.1977899409
BXD34 m 150.75 15.1935684813 180.7157818197 120.7842181803
BXD39 m 225.2 13.589540778 252.0022100591 198.3977899409
BXD40 m 111.0 15.1935684813 140.9657818197 81.0342181803
BXD43 m 144.5 15.1935684813 174.4657818197 114.5342181803
BXD44 m 315.0 15.1935684813 344.9657818197 285.0342181803
BXD45 m 142.0 15.1935684813 171.9657818197 112.0342181803
BXD48 m 125.25 15.1935684813 155.2157818197 95.2842181803
BXD48a m 158.6 13.589540778 185.4022100591 131.7977899409
BXD49 m 130.0 15.1935684813 159.9657818197 100.0342181803
BXD50 m 156.75 15.1935684813 186.7157818197 126.7842181803
BXD51 m 125.25 15.1935684813 155.2157818197 95.2842181803
BXD53 m 95.0 13.589540778 121.8022100591 68.1977899409
BXD55 m 108.4 13.589540778 135.2022100591 81.5977899409
BXD56 m 139.0 13.589540778 165.8022100591 112.1977899409
BXD6 m 120.4 13.589540778 147.2022100591 93.5977899409
BXD60 m 119.6 13.589540778 146.4022100591 92.7977899409
BXD61 m 108.6666666667 17.5440217053 143.2681710669 74.0651622665
BXD62 m 127.25 15.1935684813 157.2157818197 97.2842181803
BXD63 m 187.0 13.589540778 213.8022100591 160.1977899409
BXD64 m 180.25 15.1935684813 210.2157818197 150.2842181803
BXD65 m 181.25 15.1935684813 211.2157818197 151.2842181803
BXD65a m 218.8 13.589540778 245.6022100591 191.9977899409
BXD65b m 194.75 15.1935684813 224.7157818197 164.7842181803
BXD66 m 118.0 15.1935684813 147.9657818197 88.0342181803
BXD67 m 116.8 13.589540778 143.6022100591 89.9977899409
BXD68 m 141.2 13.589540778 168.0022100591 114.3977899409
BXD69 m 360.0 13.589540778 386.8022100591 333.1977899409
BXD70 m 87.25 15.1935684813 117.2157818197 57.2842181803
BXD71 m 144.6 13.589540778 171.4022100591 117.7977899409
BXD73 m 157.0 15.1935684813 186.9657818197 127.0342181803
BXD73a m 136.75 15.1935684813 166.7157818197 106.7842181803
BXD73b m 168.2 13.589540778 195.0022100591 141.3977899409
BXD75 m 118.0 13.589540778 144.8022100591 91.1977899409
BXD77 m 129.6 13.589540778 156.4022100591 102.7977899409
BXD79 m 156.8 13.589540778 183.6022100591 129.9977899409
BXD8 m 100.0 15.1935684813 129.9657818197 70.0342181803
BXD81 m 104.0 15.1935684813 133.9657818197 74.0342181803
BXD83 m 128.3333333333 17.5440217053 162.9348377335 93.7318289331
BXD84 m 187.8 13.589540778 214.6022100591 160.9977899409
BXD85 m 236.2 13.589540778 263.0022100591 209.3977899409
BXD87 m 114.8 13.589540778 141.6022100591 87.9977899409
BXD89 m 83.5 15.1935684813 113.4657818197 53.5342181803
BXD90 m 101.5 15.1935684813 131.4657818197 71.5342181803
BXD95 m 148.0 15.1935684813 177.9657818197 118.0342181803
BXD98 m 176.2 13.589540778 203.0022100591 149.3977899409
BXD99 m 126.6 13.589540778 153.4022100591 99.7977899409
C57BL/6J m 122.75 15.1935684813 152.7157818197 92.7842181803
DBA/2J m 95.0 15.1935684813 124.9657818197 65.0342181803




  GWAS USING LINEAR MIXED MODELS