Project measure / variable:   Auwerx1   ogtt_gluc_t60_HFD

ID, description, units MPD:111253   ogtt_gluc_t60_HFD   glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 60 min   [mg/dL]  HFD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   56 strains     sex: m     age: 17wks
Procedure glucose tolerance
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  STRAIN COMPARISON PLOT
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Auwerx1 - glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 60 min HFD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested56 strains
Mean of the strain means386.3   mg/dL
Median of the strain means361.2   mg/dL
SD of the strain means± 112.9
Coefficient of variation (CV)0.2922
Min–max range of strain means205.0   –   596.6   mg/dL
Mean sample size per strain4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 55 3155284.3541 57368.8064 10.6048 < 0.0001
Residuals 192 1038662.3556 5409.6998


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 359.4 64.3   5 28.755 0.1789 278.0, 438.0 -0.24
BXD100 m 348.6 93.76   5 41.933 0.269 262.0, 495.0 -0.33
BXD101 m 252.5 37.242   4 18.621 0.1475 217.0, 289.0 -1.19
BXD11 m 314.2 95.64   5 42.772 0.3044 174.0, 410.0 -0.64
BXD12 m 243.8 57.46   5 25.695 0.2357 184.0, 332.0 -1.26
BXD16 m 509.2 99.16   5 44.346 0.1947 397.0, 590.0 1.09
BXD2 m 250.0 46.835   5 20.945 0.1873 180.0, 305.0 -1.21
BXD27 m 586.5 22.576   4 11.288 0.0385 553.0, 600.0 1.77
BXD32 m 362.0 185.2   3 106.9 0.5115 232.0, 574.0 -0.22
BXD34 m 335.0 84.81   5 37.93 0.2532 195.0, 408.0 -0.45
BXD39 m 559.4 44.111   5 19.727 0.0789 494.0, 600.0 1.53
BXD40 m 367.2 22.411   4 11.205 0.061 343.0, 394.0 -0.17
BXD43 m 463.0 14.107   3 8.1445 0.0305 448.0, 476.0 0.68
BXD44 m 584.8 45.667   9 15.222 0.0781 463.0, 600.0 1.76
BXD45 m 283.0 30.452   4 15.226 0.1076 258.0, 327.0 -0.92
BXD48 m 464.2 88.5   4 44.248 0.1906 391.0, 593.0 0.69
BXD48a m 451.0 182.9   3 105.6 0.4056 240.0, 565.0 0.57
BXD49 m 219.5 32.46   4 16.23 0.1479 182.0, 261.0 -1.48
BXD50 m 291.2 36.928   5 16.515 0.1268 244.0, 339.0 -0.84
BXD51 m 367.0 73.33   4 36.667 0.1998 281.0, 452.0 -0.17
BXD53 m 458.8 94.92   5 42.449 0.2069 340.0, 600.0 0.64
BXD55 m 231.0 24.042   4 12.021 0.1041 195.0, 245.0 -1.38
BXD56 m 420.2 44.754   4 22.377 0.1065 382.0, 485.0 0.3
BXD6 m 324.6 27.754   5 12.412 0.0855 291.0, 356.0 -0.55
BXD60 m 346.6 21.698   5 9.7036 0.0626 327.0, 379.0 -0.35
BXD61 m 332.0 102.8   5 45.977 0.3097 270.0, 513.0 -0.48
BXD62 m 360.5 139.0   4 69.52 0.3857 279.0, 568.0 -0.23
BXD63 m 546.5 41.089   4 20.545 0.0752 507.0, 600.0 1.42
BXD64 m 511.2 121.4   4 60.71 0.2375 341.0, 600.0 1.11
BXD65 m 350.8 122.2   4 61.1 0.3484 231.0, 511.0 -0.31
BXD65a m 472.2 53.62   4 26.812 0.1136 424.0, 529.0 0.76
BXD66 m 250.8 31.479   4 15.739 0.1255 217.0, 293.0 -1.2
BXD67 m 434.6 49.863   5 22.299 0.1147 386.0, 518.0 0.43
BXD68 m 406.8 86.92   4 43.461 0.2137 294.0, 491.0 0.18
BXD69 m 590.8 20.572   5 9.2 0.0348 554.0, 600.0 1.81
BXD70 m 301.0 142.2   4 71.11 0.4725 178.0, 503.0 -0.76
BXD71 m 544.0 96.99   3 56.0 0.1783 432.0, 600.0 1.4
BXD73 m 319.0 66.45   5 29.719 0.2083 228.0, 412.0 -0.6
BXD73a m 284.0 32.588   4 16.294 0.1147 261.0, 332.0 -0.91
BXD73b m 289.0 87.78   5 39.258 0.3038 210.0, 426.0 -0.86
BXD75 m 386.8 87.2   5 38.998 0.2254 290.0, 489.0 0.0
BXD77 m 475.2 77.37   5 34.603 0.1628 340.0, 529.0 0.79
BXD79 m 367.2 81.31   5 36.364 0.2214 267.0, 449.0 -0.17
BXD8 m 270.2 54.34   5 24.303 0.2011 218.0, 342.0 -1.03
BXD81 m 508.8 43.37   4 21.685 0.0852 457.0, 552.0 1.09
BXD83 m 318.2 94.75   4 47.377 0.2977 225.0, 439.0 -0.6
BXD84 m 560.0 44.306   3 25.58 0.0791 509.0, 589.0 1.54
BXD85 m 533.8 71.09   4 35.544 0.1332 460.0, 600.0 1.31
BXD87 m 328.8 57.67   5 25.79 0.1754 254.0, 405.0 -0.51
BXD89 m 230.5 83.48   4 41.738 0.3622 122.0, 309.0 -1.38
BXD90 m 253.5 22.811   4 11.405 0.09 236.0, 287.0 -1.18
BXD95 m 433.2 38.906   5 17.399 0.0898 404.0, 488.0 0.42
BXD98 m 596.6 7.6026   5 3.4 0.0127 583.0, 600.0 1.86
BXD99 m 483.8 71.18   5 31.831 0.1471 386.0, 564.0 0.86
C57BL/6J m 295.8 52.8   4 26.402 0.1785 245.0, 370.0 -0.8
DBA/2J m 205.0 57.17   3 33.005 0.2789 159.0, 269.0 -1.61


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 359.4 32.8928556636 424.2777531002 294.5222468998
BXD100 m 348.6 32.8928556636 413.4777531002 283.7222468998
BXD101 m 252.5 36.7753306189 325.0355330797 179.9644669203
BXD11 m 314.2 32.8928556636 379.0777531002 249.3222468998
BXD12 m 243.8 32.8928556636 308.6777531002 178.9222468998
BXD16 m 509.2 32.8928556636 574.0777531002 444.3222468998
BXD2 m 250.0 32.8928556636 314.8777531002 185.1222468998
BXD27 m 586.5 36.7753306189 659.0355330797 513.9644669203
BXD32 m 362.0 42.4644940647 445.7568190987 278.2431809013
BXD34 m 335.0 32.8928556636 399.8777531002 270.1222468998
BXD39 m 559.4 32.8928556636 624.2777531002 494.5222468998
BXD40 m 367.25 36.7753306189 439.7855330797 294.7144669203
BXD43 m 463.0 42.4644940647 546.7568190988 379.2431809013
BXD44 m 584.7777777778 24.5168870793 633.1347998309 536.4207557246
BXD45 m 283.0 36.7753306189 355.5355330797 210.4644669203
BXD48 m 464.25 36.7753306189 536.7855330797 391.7144669203
BXD48a m 451.0 42.4644940647 534.7568190987 367.2431809013
BXD49 m 219.5 36.7753306189 292.0355330797 146.9644669203
BXD50 m 291.2 32.8928556636 356.0777531002 226.3222468998
BXD51 m 367.0 36.7753306189 439.5355330797 294.4644669203
BXD53 m 458.8 32.8928556636 523.6777531002 393.9222468998
BXD55 m 231.0 36.7753306189 303.5355330797 158.4644669203
BXD56 m 420.25 36.7753306189 492.7855330797 347.7144669203
BXD6 m 324.6 32.8928556636 389.4777531002 259.7222468998
BXD60 m 346.6 32.8928556636 411.4777531002 281.7222468998
BXD61 m 332.0 32.8928556636 396.8777531002 267.1222468998
BXD62 m 360.5 36.7753306189 433.0355330797 287.9644669203
BXD63 m 546.5 36.7753306189 619.0355330797 473.9644669203
BXD64 m 511.25 36.7753306189 583.7855330797 438.7144669203
BXD65 m 350.75 36.7753306189 423.2855330797 278.2144669203
BXD65a m 472.25 36.7753306189 544.7855330797 399.7144669203
BXD66 m 250.75 36.7753306189 323.2855330797 178.2144669203
BXD67 m 434.6 32.8928556636 499.4777531002 369.7222468998
BXD68 m 406.75 36.7753306189 479.2855330797 334.2144669203
BXD69 m 590.8 32.8928556636 655.6777531002 525.9222468998
BXD70 m 301.0 36.7753306189 373.5355330797 228.4644669203
BXD71 m 544.0 42.4644940647 627.7568190987 460.2431809013
BXD73 m 319.0 32.8928556636 383.8777531002 254.1222468998
BXD73a m 284.0 36.7753306189 356.5355330797 211.4644669203
BXD73b m 289.0 32.8928556636 353.8777531002 224.1222468998
BXD75 m 386.8 32.8928556636 451.6777531002 321.9222468998
BXD77 m 475.2 32.8928556636 540.0777531002 410.3222468998
BXD79 m 367.2 32.8928556636 432.0777531002 302.3222468998
BXD8 m 270.2 32.8928556636 335.0777531002 205.3222468998
BXD81 m 508.75 36.7753306189 581.2855330797 436.2144669203
BXD83 m 318.25 36.7753306189 390.7855330797 245.7144669203
BXD84 m 560.0 42.4644940647 643.7568190987 476.2431809013
BXD85 m 533.75 36.7753306189 606.2855330797 461.2144669203
BXD87 m 328.8 32.8928556636 393.6777531002 263.9222468998
BXD89 m 230.5 36.7753306189 303.0355330797 157.9644669203
BXD90 m 253.5 36.7753306189 326.0355330797 180.9644669203
BXD95 m 433.2 32.8928556636 498.0777531002 368.3222468998
BXD98 m 596.6 32.8928556636 661.4777531002 531.7222468998
BXD99 m 483.8 32.8928556636 548.6777531002 418.9222468998
C57BL/6J m 295.75 36.7753306189 368.2855330797 223.2144669203
DBA/2J m 205.0 42.4644940647 288.7568190987 121.2431809013




  GWAS USING LINEAR MIXED MODELS