Project measure / variable:   Auwerx1   ogtt_gluc_t60_CD

ID, description, units MPD:111252   ogtt_gluc_t60_CD   glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 60 min   [mg/dL]  CD  
high-fat diet study
Data set, strains Auwerx1   BXD w/par   57 strains     sex: m     age: 17wks
Procedure glucose tolerance
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  STRAIN COMPARISON PLOT
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Auwerx1 - glucose, glucose tolerance test (20% glucose oral gavage, overnight fast), after 60 min CD



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested57 strains
Mean of the strain means257.2   mg/dL
Median of the strain means233.0   mg/dL
SD of the strain means± 87.93
Coefficient of variation (CV)0.3419
Min–max range of strain means137.5   –   530.5   mg/dL
Mean sample size per strain4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 56 2214293.8127 39540.9609 14.7392 < 0.0001
Residuals 198 531176.3833 2682.709


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD1 m 196.4 22.323   5 9.983 0.1137 173.0, 228.0 -0.69
BXD100 m 355.3 33.292   3 19.221 0.0937 327.0, 392.0 1.12
BXD101 m 228.0 21.463   4 10.732 0.0941 209.0, 249.0 -0.33
BXD11 m 231.0 87.87   4 43.937 0.3804 114.0, 327.0 -0.3
BXD12 m 175.4 15.884   5 7.1035 0.0906 149.0, 187.0 -0.93
BXD16 m 383.8 106.5   4 53.24 0.2775 245.0, 489.0 1.44
BXD2 m 207.8 17.914   4 8.9571 0.0862 192.0, 227.0 -0.56
BXD27 m 473.4 103.3   5 46.199 0.2182 358.0, 580.0 2.46
BXD32 m 210.4 25.589   5 11.444 0.1216 173.0, 243.0 -0.53
BXD34 m 325.5 64.6   4 32.302 0.1985 255.0, 410.0 0.78
BXD39 m 347.0 32.148   5 14.377 0.0926 308.0, 393.0 1.02
BXD40 m 231.2 43.454   4 21.727 0.1879 179.0, 269.0 -0.3
BXD43 m 343.0 29.337   4 14.669 0.0855 304.0, 368.0 0.98
BXD44 m 530.5 69.37   8 24.526 0.1308 393.0, 600.0 3.11
BXD45 m 223.0 9.9666   4 4.9833 0.0447 213.0, 233.0 -0.39
BXD48 m 264.0 43.597   4 21.798 0.1651 219.0, 323.0 0.08
BXD48a m 260.2 46.322   5 20.716 0.178 189.0, 314.0 0.03
BXD49 m 211.8 21.093   4 10.547 0.0996 187.0, 233.0 -0.52
BXD50 m 267.5 36.937   4 18.468 0.1381 225.0, 307.0 0.12
BXD51 m 179.0 20.0   4 10.0 0.1117 157.0, 205.0 -0.89
BXD53 m 195.0 44.452   5 19.88 0.228 138.0, 252.0 -0.71
BXD55 m 172.6 19.424   5 8.6868 0.1125 150.0, 196.0 -0.96
BXD56 m 284.6 99.89   5 44.671 0.351 195.0, 443.0 0.31
BXD6 m 210.6 21.149   5 9.4583 0.1004 185.0, 234.0 -0.53
BXD60 m 201.8 58.46   5 26.143 0.2897 109.0, 257.0 -0.63
BXD61 m 191.0 23.065   3 13.317 0.1208 169.0, 215.0 -0.75
BXD62 m 167.5 14.933   4 7.4666 0.0892 156.0, 189.0 -1.02
BXD63 m 347.8 56.36   5 25.204 0.162 284.0, 415.0 1.03
BXD64 m 253.5 45.2   4 22.6 0.1783 192.0, 300.0 -0.04
BXD65 m 307.2 88.22   4 44.109 0.2871 204.0, 419.0 0.57
BXD65a m 349.6 125.6   5 56.19 0.3594 263.0, 569.0 1.05
BXD65b m 265.2 53.62   4 26.809 0.2021 213.0, 338.0 0.09
BXD66 m 207.8 33.42   4 16.71 0.1609 159.0, 233.0 -0.56
BXD67 m 243.2 29.953   5 13.396 0.1232 216.0, 292.0 -0.16
BXD68 m 260.8 50.7   5 22.672 0.1944 201.0, 337.0 0.04
BXD69 m 524.2 87.96   5 39.335 0.1678 385.0, 600.0 3.04
BXD70 m 137.5 41.413   4 20.706 0.3012 92.0, 191.0 -1.36
BXD71 m 354.8 36.996   5 16.545 0.1043 305.0, 390.0 1.11
BXD73 m 218.2 9.0692   4 4.5346 0.0416 209.0, 227.0 -0.44
BXD73a m 233.0 13.736   4 6.8678 0.059 213.0, 244.0 -0.27
BXD73b m 297.8 25.144   5 11.245 0.0844 274.0, 325.0 0.46
BXD75 m 235.4 40.979   5 18.326 0.1741 202.0, 304.0 -0.25
BXD77 m 265.2 42.863   5 19.169 0.1616 209.0, 323.0 0.09
BXD79 m 193.4 41.86   5 18.721 0.2164 141.0, 243.0 -0.73
BXD8 m 166.5 38.284   4 19.142 0.2299 115.0, 206.0 -1.03
BXD81 m 168.8 21.093   4 10.547 0.125 140.0, 186.0 -1.0
BXD83 m 164.7 8.6217   3 4.9777 0.0524 157.0, 174.0 -1.05
BXD84 m 237.6 29.678   5 13.273 0.1249 205.0, 273.0 -0.22
BXD85 m 405.6 60.86   5 27.217 0.15 325.0, 471.0 1.69
BXD87 m 224.6 32.738   5 14.641 0.1458 176.0, 258.0 -0.37
BXD89 m 177.2 4.6458   4 2.3229 0.0262 173.0, 183.0 -0.91
BXD90 m 166.2 24.958   4 12.479 0.1501 144.0, 202.0 -1.03
BXD95 m 261.0 34.9   4 17.45 0.1337 233.0, 312.0 0.04
BXD98 m 331.6 69.82   5 31.226 0.2106 244.0, 426.0 0.85
BXD99 m 243.2 58.33   5 26.087 0.2399 175.0, 311.0 -0.16
C57BL/6J m 205.5 52.79   4 26.396 0.2569 171.0, 284.0 -0.59
DBA/2J m 143.5 26.489   4 13.244 0.1846 119.0, 178.0 -1.29


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD1 m 196.4 23.163371977 242.0785743843 150.7214256156
BXD100 m 355.3333333333 29.9037846364 414.3041192897 296.362547377
BXD101 m 228.0 25.8974371644 279.0701987193 176.9298012807
BXD11 m 231.0 25.8974371644 282.0701987193 179.9298012807
BXD12 m 175.4 23.163371977 221.0785743844 129.7214256157
BXD16 m 383.75 25.8974371644 434.8201987193 332.6798012807
BXD2 m 207.75 25.8974371644 258.8201987193 156.6798012807
BXD27 m 473.4 23.163371977 519.0785743844 427.7214256157
BXD32 m 210.4 23.163371977 256.0785743844 164.7214256157
BXD34 m 325.5 25.8974371644 376.5701987193 274.4298012807
BXD39 m 347.0 23.163371977 392.6785743844 301.3214256156
BXD40 m 231.25 25.8974371644 282.3201987193 180.1798012807
BXD43 m 343.0 25.8974371644 394.0701987193 291.9298012807
BXD44 m 530.5 18.3122534343 566.612083831 494.387916169
BXD45 m 223.0 25.8974371644 274.0701987193 171.9298012807
BXD48 m 264.0 25.8974371644 315.0701987193 212.9298012807
BXD48a m 260.2 23.163371977 305.8785743844 214.5214256157
BXD49 m 211.75 25.8974371644 262.8201987193 160.6798012807
BXD50 m 267.5 25.8974371644 318.5701987193 216.4298012807
BXD51 m 179.0 25.8974371644 230.0701987193 127.9298012807
BXD53 m 195.0 23.163371977 240.6785743844 149.3214256156
BXD55 m 172.6 23.163371977 218.2785743844 126.9214256157
BXD56 m 284.6 23.163371977 330.2785743844 238.9214256156
BXD6 m 210.6 23.163371977 256.2785743844 164.9214256156
BXD60 m 201.8 23.163371977 247.4785743844 156.1214256156
BXD61 m 191.0 29.9037846364 249.9707859564 132.0292140436
BXD62 m 167.5 25.8974371644 218.5701987193 116.4298012807
BXD63 m 347.8 23.163371977 393.4785743843 302.1214256156
BXD64 m 253.5 25.8974371644 304.5701987193 202.4298012807
BXD65 m 307.25 25.8974371644 358.3201987193 256.1798012807
BXD65a m 349.6 23.163371977 395.2785743844 303.9214256157
BXD65b m 265.25 25.8974371644 316.3201987193 214.1798012807
BXD66 m 207.75 25.8974371644 258.8201987193 156.6798012807
BXD67 m 243.2 23.163371977 288.8785743844 197.5214256157
BXD68 m 260.8 23.163371977 306.4785743844 215.1214256157
BXD69 m 524.2 23.163371977 569.8785743844 478.5214256157
BXD70 m 137.5 25.8974371644 188.5701987193 86.4298012807
BXD71 m 354.8 23.163371977 400.4785743844 309.1214256157
BXD73 m 218.25 25.8974371644 269.3201987193 167.1798012807
BXD73a m 233.0 25.8974371644 284.0701987193 181.9298012807
BXD73b m 297.8 23.163371977 343.4785743844 252.1214256157
BXD75 m 235.4 23.163371977 281.0785743844 189.7214256157
BXD77 m 265.2 23.163371977 310.8785743844 219.5214256157
BXD79 m 193.4 23.163371977 239.0785743844 147.7214256157
BXD8 m 166.5 25.8974371644 217.5701987193 115.4298012807
BXD81 m 168.75 25.8974371644 219.8201987193 117.6798012807
BXD83 m 164.6666666667 29.9037846364 223.637452623 105.6958807103
BXD84 m 237.6 23.163371977 283.2785743844 191.9214256157
BXD85 m 405.6 23.163371977 451.2785743844 359.9214256157
BXD87 m 224.6 23.163371977 270.2785743844 178.9214256157
BXD89 m 177.25 25.8974371644 228.3201987193 126.1798012807
BXD90 m 166.25 25.8974371644 217.3201987193 115.1798012807
BXD95 m 261.0 25.8974371644 312.0701987193 209.9298012807
BXD98 m 331.6 23.163371977 377.2785743844 285.9214256157
BXD99 m 243.2 23.163371977 288.8785743844 197.5214256157
C57BL/6J m 205.5 25.8974371644 256.5701987193 154.4298012807
DBA/2J m 143.5 25.8974371644 194.5701987193 92.4298012807




  GWAS USING LINEAR MIXED MODELS