MPD: Data set: Richards-Smith1

Richards-Smith1: Fat, carbohydrate, and calorie intake for F2 reciprocal crosses involving C57BL/6J and CAST/EiJ on a self-selected macronutrient diet (2002)

Smith Richards BK, Belton BN, Poole AC, Mancuso JJ, Churchill GA, Li R, Volaufova J, Zuberi A, York B. QTL analysis of self-selected macronutrient diet intake: fat, carbohydrate, and total kilocalories. Physiol Genomics. 2002 Dec 3;11(3):205-17. Epub 2002 Dec 3. PubMed 12388789

Kumar KG, Byerley LO, Volaufova J, Drucker DJ, Churchill GA, Li R, York B, Zuberi A, Richards BK. Genetic variation in Glp1r expression influences the rate of gastric emptying in mice. Am J Physiol Regul Integr Comp Physiol. 2008 Feb;294(2):R362-7Epub 2007 Dec 12. PubMed 18077508

Richards-Smith1 downloads
QTL projects have several available downloads.
Use the QTL Data Downloads button near the bottom of this page.

Ontology terms mapped to Richards-Smith1 measures:

MA:0002502 serum
MA:0002549 retroperitoneal fat pad
MA:0002550 epididymal fat pad
MP:0000188 abnormal circulating glucose level
MP:0001259 abnormal body weight
MP:0001432 abnormal food preference
MP:0001731 abnormal postnatal growth
MP:0005337 abnormal retroperitoneal fat pad morphology
MP:0006319 abnormal epididymal fat pad morphology
MP:0011117 abnormal susceptibility to weight gain
VT:0000188 blood glucose amount
VT:0001259 body mass
VT:0001431 eating behavior trait
VT:0010421 epididymal fat pad mass
VT:0010430 retroperitoneal fat pad mass
VT:0100007 growth trait

Investigators	Beverly K Richards-Smith The Jackson Laboratory, Bar Harbor, ME Gary A Churchill The Jackson Laboratory, Bar Harbor, ME
Participants	Kumar KG, Byerley LO, Volaufova J, Drucker DJ, Li R, York B, Zuberi A
Contact	Gary A Churchill gary.churchill@jax.org
Affiliated Center	QTL Archive
Project type	QTL Archive data set
MPD identifiers	Richards-Smith1 MPD:124
Data changelog	No updates/corrections. Initial release date: 01/2008.

QTL data set parameters:

Progenitor strains	C57BL/6J CAST/EiJ
Cross direction notation	see Excel file
Cross type	F2 intercross
Population size	0 ♀ 502 ♂

Measured phenotypes: To access these data use the QTL Data Downloads button at bottom of page.

Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	Sex	Age	Sample Size (Avg)
Richards-Smith1	body weight	(none)	body weight as measured at the beginning of the 10-day phenotyping period. [g] Pre-Diet-bwt 12401	QTL population	m	8-12wks	N=502

Richards-Smith1	body weight	macronutrient diet option	body weights as measured at the end of the 10 day phenotyping period. [g] Post-diet-Bw 12402	QTL population	m	9-13wks	N=502

Richards-Smith1	body weight	macronutrient diet option	gained body weight after diet (difference) [g] Bw-gain 12403	QTL population	m	9-13wks	N=502

Richards-Smith1	intake monitoring	macronutrient diet option	10 day sum of kilocalories consumed from the carbohydrate/protein diet choice [kcal] 10d-sum-C/P-Kcal 12404	QTL population	m	9-13wks	N=502

Richards-Smith1	intake monitoring	macronutrient diet option	10 day sum of kilocalories consumed from the fat/protein diet choice [kcal] 10d-sum-F/P-Kcal 12405	QTL population	m	9-13wks	N=502

Richards-Smith1	intake monitoring	macronutrient diet option	10 day sum of total daily kilocalories consumed from the fat/protein and carbohydrate/protein diets [kcal] 10d-sum-tot-Kcal 12406	QTL population	m	9-13wks	N=502

Richards-Smith1	intake monitoring	macronutrient diet option	preference of Fat/Protein diet over carbohydrate/protein diet [ratio] F/P-preference 12407	QTL population	m	9-13wks	N=502

Richards-Smith1	metabolic panel	macronutrient diet option	glucose (serum) [mg/dL] Serum-glucose 12409	QTL population	m	9-13wks	N=502

Richards-Smith1	fat pad weights	macronutrient diet option	bilat retroperitoneal fat [g] RP 12410	QTL population	m	9-13wks	N=502

Richards-Smith1	fat pad weights	macronutrient diet option	bilat epididymal fat [g] EPI 12411	QTL population	m	9-13wks	N=502

Associated genomic features

MGI-curated QTL / genomic features that have been associated with this data set:
Kcal1 Kcal2 Kcal3 Mnic1 Mnic2 Mnic3 Mnif1 Mnif2 Mnif3 Tfv1

Project / data set: Richards-Smith1 a.k.a. Smith_2002
Excel file: ._Data_Description_B6xCAST_Smith2002.xlsx
Excel file: Data_Description_B6xCAST_Smith2002.xlsx
CSV file: Smith2002_B6xCAST_B37_Data.csv
Readme / text file: readme_Smith2002.txt