MPD: Data set: Project1140

Project1140: Shock Center Longitudinal Aging Study (None) [Pending]

Churchill GA, Korstanje R, Gatti DM, Luciano A

Project1140 downloads
• Download Project1140 project data set animal data, as uploaded
• Download Project1140 animal data matrix with factor-related expansion applied as necessary
• Download Project1140 strain means, SD, N, etc. one row per strain/sex/measure
• Download Project1140 supplementary file, JAC_DO_phenotypes_compiled_descr_v8.csv

Ontology terms mapped to Project1140 measures:

MA:0000008 tail
MA:0000059 blood
MA:0000326 reproductive system
MA:0002502 serum
MA:0002545 urine
MP:0000188 abnormal circulating glucose level
MP:0000217 abnormal leukocyte cell number
MP:0000226 abnormal mean corpuscular volume
MP:0000717 abnormal lymphocyte cell number
MP:0001259 abnormal body weight
MP:0001586 abnormal erythrocyte cell number
MP:0001588 abnormal hemoglobin
MP:0001589 abnormal mean corpuscular hemoglobin
MP:0001771 abnormal circulating magnesium level
MP:0001776 abnormal circulating sodium level
MP:0002586 abnormal platelet volume
MP:0002596 abnormal hematocrit
MP:0002602 abnormal eosinophil cell number
MP:0002668 abnormal circulating potassium level
MP:0002900 abnormal urine phosphate level
MP:0004700 abnormal circulating insulin-like growth factor I level
MP:0005265 abnormal blood urea nitrogen level
MP:0005397 hematopoietic system phenotype
MP:0005640 abnormal mean corpuscular hemoglobin concentration
MP:0008849 abnormal hemoglobin concentration distribution width
MP:0009548 abnormal platelet aggregation
MP:0010066 abnormal red blood cell distribution width
MP:0011434 abnormal urine magnesium level
MP:0011469 abnormal urine creatinine level
MP:0011898 abnormal platelet cell number
MP:0011913 abnormal reticulocyte cell number
MP:0011999 abnormal tail length
MP:0012397 abnormal nucleated erythrocyte cell number
MP:0012440 abnormal neutrophil cell number
MP:0012441 abnormal monocyte cell number
MP:0020150 abnormal timing of vaginal opening
MP:0020153 abnormal urine albumin level
VT:0000188 blood glucose amount
VT:0000217 leukocyte quantity
VT:0000222 neutrophil quantity
VT:0000223 monocyte quantity
VT:0000237 blood cell quantity
VT:0000248 erythrocyte size trait
VT:0000717 lymphocyte quantity
VT:0001142 vaginal opening morphology trait
VT:0001259 body mass
VT:0001586 erythrocyte quantity
VT:0001588 blood hemoglobin amount
VT:0001661 total life span
VT:0001757 urine molecular composition trait
VT:0001771 blood magnesium amount
VT:0001776 blood sodium amount
VT:0002136 kidney physiology trait
VT:0002424 reticulocyte morphology trait
VT:0002447 erythrocyte morphology trait
VT:0002602 eosinophil quantity
VT:0002636 time of vaginal opening
VT:0002668 blood potassium amount
VT:0002758 tail length
VT:0002871 urine albumin amount
VT:0002900 urine phosphate amount
VT:0003135 reticulocyte quantity
VT:0003179 platelet quantity
VT:0004152 blood iron amount
VT:0005265 blood urea nitrogen amount
VT:0010183 platelet morphology trait
VT:0010457 platelet size trait
VT:0010479 blood insulin-like growth factor amount
VT:0010540 urine creatinine amount
VT:3000002 platelet aggregation trait

Investigators	Gary A Churchill The Jackson Laboratory, Bar Harbor, ME Ron Korstanje The Jackson Laboratory, Bar Harbor, ME Daniel M Gatti The Jackson Laboratory, Bar Harbor, ME Alison Luciano The Jackson Laboratory, Bar Harbor, ME
Contact	Gary A Churchill gary.churchill@jax.org Lab web site
Affiliated Center	JAX Nathan Shock Aging Center
Funding Provided By	National Institute on Aging
Project type	Phenotype strain survey data set
MPD identifiers	Project1140 MPD:1140
Data changelog	This project has not yet been released.
Formatted citation	Click above to copy-paste the entire citation for this MPD web page.

[No procedure abstracts have been defined yet]

Diverstiy Outbred mice of both sexes were aged, phenotyped, and followed throughout their natural lifespan.

Experimental groups in this study:
• Chow diet

Mice: DO population ♀♂ age varies 1 experimental group

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	Sex	Age	Sample Size (Avg)
Project1140:7	Project1140	colony observation	(none)	age at vaginal patency [days] Age_of_VP 116499	DO population	f	3-6 wks	N=300

Project1140:9	Project1140	body weight	(none)	body weight at vaginal patency [g] bw_vp 116501	DO population	f	3-6 wks	N=300

Project1140:12	Project1140	body weight	(none)	body weight [g] bw 116504 bw_29 bw_31 bw_33 bw_55 bw_57 bw_59 bw_81 bw_83 bw_85 bw_104 bw_130	DO population	both	29-130 wks	N=230

Project1140:47	Project1140	metabolic panel	(none)	sodium (blood Na) measurement [mmol/L] sodium 116539 sodium_6 sodium_12 sodium_18	DO population	both	27-83 wks	N=257

Project1140:50	Project1140	metabolic panel	(none)	potassium (blood K) measurement [mmol/L] potassium 116542 potas_6 potas_12 potas_18	DO population	both	27-83 wks	N=257

Project1140:53	Project1140	metabolic panel	(none)	blood urea nitrogen (BUN) measurement [mg/dL] bun 116545 bun_6 bun_12 bun_18	DO population	both	27-83 wks	N=258

Project1140:56	Project1140	metabolic panel	(none)	magnesium (serum Mg) measurement [mg/dL] mg 116548 mg_6 mg_12 mg_18	DO population	both	27-83 wks	N=258

Project1140:59	Project1140	complete blood count	(none)	white blood cell count (WBC; units per volume x 10³) [n/µL] wbc 116551 wbc_6 wbc_12 wbc_18	DO population	both	30-85 wks	N=260

Project1140:62	Project1140	complete blood count	(none)	red blood cell count (RBC; units per volume x 10⁶) [n/µL] rbc 116554 rbc_6 rbc_12 rbc_18	DO population	both	30-85 wks	N=260

Project1140:65	Project1140	complete blood count	(none)	measured hemoglobin [g/dL] hgb 116557 hgb_6 hgb_12 hgb_18	DO population	both	30-85 wks	N=260

Project1140:68	Project1140	complete blood count	(none)	calculated hemoglobin (cHGB) [g/dL] chgb 116560 chgb_6 chgb_12 chgb_18	DO population	both	30-85 wks	N=260

Project1140:71	Project1140	complete blood count	(none)	hematocrit (HCT) [%] hct 116563 hct_6 hct_12 hct_18	DO population	both	30-85 wks	N=260

Project1140:74	Project1140	complete blood count	(none)	mean RBC corpuscular volume (MCV) [fL] mcv 116566 mcv_6 mcv_12 mcv_18	DO population	both	30-85 wks	N=260

Project1140:77	Project1140	complete blood count	(none)	mean RBC corpuscular hemoglobin (MCH) [pg] mch 116569 mch_6 mch_12 mch_18	DO population	both	30-85 wks	N=260

Project1140:80	Project1140	complete blood count	(none)	mean RBC corpuscular hemoglobin concentration (MCHC) [g/dL] mchc 116572 mchc_6 mchc_12 mchc_18	DO population	both	30-85 wks	N=260

Project1140:83	Project1140	complete blood count	(none)	mean cellular hemoglobin content (CH) [pg] ch 116575 ch_6 ch_12 ch_18	DO population	both	’30-85 wks	N=260

Project1140:86	Project1140	complete blood count	(none)	mean reticulocyte hemoglobin content (CHR) [pg] chr 116578 chr_6 chr_12 chr_18	DO population	both	30-85 wks	N=216

Project1140:89	Project1140	complete blood count	(none)	RBC corpuscular hemoglobin concentration mean (CHCM) [g/dL] chcm 116581 chcm_6 chcm_12 chcm_18	DO population	both	30-85 wks	N=260

Project1140:92	Project1140	complete blood count	(none)	RBC corpuscular distribution width (RDW) [%] rdw 116584 rdw_6 rdw_12 rdw_18	DO population	both	30-85 wks	N=260

Project1140:95	Project1140	complete blood count	(none)	hemoglobin concentration distribution width (HDW) [g/dL] hdw 116587 hdw_6 hdw_12 hdw_18	DO population	both	30-85 wks	N=260

Project1140:101	Project1140	complete blood count	(none)	Platelet clumps [n] clumps 116593 clumps_6 clumps_12 clumps_18	DO population	both	30-85 wks	N=260

Project1140:104	Project1140	complete blood count	(none)	platelet count (PLT; units per volume x 10³) [n/µL] plt 116596 plt_6 plt_12 plt_18	DO population	both	30-85 wks	N=260

Project1140:107	Project1140	complete blood count	(none)	mean platelet volume (MPV) [fL] mpv 116599 mpv_6 mpv_12 mpv_18	DO population	both	30-85 wks	N=260

Project1140:110	Project1140	complete blood count	(none)	mean platelet mass (MPM) [pg] mpm 116602 mpm_6 mpm_12 mpm_18	DO population	both	30-85 wks	N=260

Project1140:113	Project1140	complete blood count	(none)	neutrophil differential (NEUT; percentage of total WBC) [%] p_neut 116605 p_neut_6 p_neut_12 p_neut_18	DO population	both	30-85 wks	N=260

Project1140:116	Project1140	complete blood count	(none)	lymphocyte differential (LYM; percentage of total WBC) [%] p_lymph 116608 p_lymph_6 p_lymph_12 p_lymph_18	DO population	both	30-85 wks	N=260

Project1140:119	Project1140	complete blood count	(none)	monocyte differential (MONO; percentage of total WBC) [%] p_mono 116611 p_mono_6 p_mono_12 p_mono_18	DO population	both	30-85 wks	N=260

Project1140:122	Project1140	complete blood count	(none)	eosinophil differential (EOS; percentage of total WBC) [%] p_eos 116614 p_eos_6 p_eos_12 p_eos_18	DO population	both	30-85 wks	N=259

Project1140:125	Project1140	complete blood count	(none)	reticulocyte differential (Retic; percentage of total RBC) [%] p_retic 116617 p_retic_6 p_retic_12 p_retic_18	DO population	both	30-85 wks	N=184

Project1140:128	Project1140	complete blood count	(none)	reticulocyte count (Retic; units per volume x 10⁹) [n/µL] n_retic 116620 n_retic_6 n_retic_12 n_retic_18	DO population	both	30-85 wks	N=184

Project1140:131	Project1140	complete blood count	(none)	neutrophil count (NEUT; per volume x 10³) [n/µL] n_neut 116623 n_neut_6 n_neut_12 n_neut_18	DO population	both	30-85 wks	N=260

Project1140:134	Project1140	complete blood count	(none)	lymphocyte count (LYM; units per volume x 10³) [n/µL] n_lymph 116626 n_lymph_6 n_lymph_12 n_lymph_18	DO population	both	30-85 wks	N=260

Project1140:137	Project1140	complete blood count	(none)	monocyte count (MONO; units per volume x 10³) [n/µL] n_mono 116629 n_mono_6 n_mono_12 n_mono_18	DO population	both	30-85 wks	N=260

Project1140:140	Project1140	complete blood count	(none)	eosinophil count (EOS; units per volume x 10³) [n/µL] n_eos 116632 n_eos_6 n_eos_12 n_eos_18	DO population	both	30-85 wks	N=259

Project1140:146	Project1140	metabolic panel	(none)	blood glucose [mmol/L] gluc 116638 gluc_6 gluc_12 gluc_18	DO population	both	32-87 wks	N=257

Project1140:152	Project1140	hormone quantification	(none)	insulin-like growth factor 1 (serum IGF-1) [ng/mL] igf1_ctrl 116644 igf1_ctrl_6 igf1_ctrl_12 igf1_ctrl_18	DO population	both	26-78 wks	N=257

Project1140:155	Project1140	hormone quantification	(none)	insulin-like growth factor 1 (serum IGF-1) 6 mo [ng/mL] igf1 116647 igf1_6 igf1_12 igf1_18	DO population	both	26-78 wks	N=257

Project1140:162	Project1140	urinalysis	(none)	urine creatinine [mg/dL] cr_u 116654 cr_u_6 cr_u_12 cr_u_18 cr_u_24 cr_u_30	DO population	both	26-130 wks	N=185

Project1140:167	Project1140	urinalysis	(none)	magnesium level (urine Mg) mg_u 116659 mg_u_6 mg_u_12 mg_u_18 mg_u_24 mg_u_30	DO population	both	26-130 wks	N=192

Project1140:172	Project1140	urinalysis	(none)	microalbumin (urine MA) [mg/dL] ma_u 116664 ma_u_6 ma_u_12 ma_u_18 ma_u_24 ma_u_30	DO population	both	26-130 wks	N=160

Project1140:177	Project1140	urinalysis	(none)	phosphorus level (urine P) [mg/dL] phs_u 116669 phs_u_6 phs_u_12 phs_u_18 phs_u_24 phs_u_30	DO population	both	26-130 wks	N=193

Project1140:182	Project1140	urinalysis	(none)	magnesium-creatinine ratio (urine MCR) [mg/g] mg_cr_u 116674 mg_cr_u_6 mg_cr_u_12 mg_cr_u_18 mg_cr_u_24 mg_cr_u_30	DO population	both	26-130 wks	N=182

Project1140:187	Project1140	urinalysis	(none)	albumin-creatinine ratio (urine ACR) [mg/g] ma_cr_u 116679 ma_cr_u_6 ma_cr_u_12 ma_cr_u_18 ma_cr_u_24 ma_cr_u_30	DO population	both	26-130 wks	N=124

Project1140:192	Project1140	urinalysis	(none)	phosphorus-creatinine ratio (urine PCR) [mg/g] phs_cr_u 116684 phs_cr_u_6 phs_cr_u_12 phs_cr_u_18 phs_cr_u_24 phs_cr_u_30	DO population	both	26-130 wks	N=183

Project1140:200	Project1140	immune cell quantification	(none)	single cells,freq. of parent_m [n] single_m 116692 single_m33 single_m59 single_m85	DO population	both	33-85 wks	N=257

Project1140:203	Project1140	immune cell quantification	(none)	single cells/viable cells,freq. of parent_m [%] viable 116695 viable_m33 viable_m59 viable_m85	DO population	both	33-85 wks	N=257

Project1140:206	Project1140	immune cell quantification	(none)	single cells/viable cells/CD11b+,freq. of parent [%] cd11b 116698 cd11b_33 cd11b_59 cd11b_85	DO population	both	33-85 wks	N=257

Project1140:209	Project1140	immune cell quantification	(none)	single cells/viable cells/CD11b+/eosinophils,freq. of parent [%] eos 116701 eos_33 eos_59 eos_85	DO population	both	33-85 wks	N=257

Project1140:212	Project1140	immune cell quantification	(none)	single cells/viable cells/CD11b+/eosinophils,freq. of,viable cells [%] eos_perc 116704 eos_perc_33 eos_perc_59 eos_perc_85	DO population	both	33-85 wks	N=257

Project1140:215	Project1140	immune cell quantification	(none)	single cells/viable cells/CD11b+/granulocytes,freq. of parent [%] gran 116707 gran_33 gran_59 gran_85	DO population	both	33-85 wks	N=257

Project1140:218	Project1140	immune cell quantification	(none)	single cells/viable cells/CD11b+/granulocytes,freq. of,viable cells [%] gran_perc 116710 gran_perc_33 gran_perc_59 gran_perc_85	DO population	both	33-85 wks	N=257

Project1140:221	Project1140	immune cell quantification	(none)	single cells/viable cells/CD11b+/monocytes,freq. of parent [%] mono 116713 mono_33 mono_59 mono_85	DO population	both	33-85 wks	N=257

Project1140:224	Project1140	immune cell quantification	(none)	single cells/viable cells/CD11b+/monocytes,freq. of,viable cells [%] mono_perc 116716 mono_perc_33 mono_perc_59 mono_perc_85	DO population	both	33-85 wks	N=257

Project1140:227	Project1140	immune cell quantification	(none)	single cells/viable cells/CD11b+/monocytes/inflammitory monocytes,freq. of parent [%] infl_mono 116719 infl_mono_33 infl_mono_59 infl_mono_85	DO population	both	33-85 wks	N=257

Project1140:230	Project1140	immune cell quantification	(none)	single cells/viable cells/CD11b+/monocytes/other monocytes,freq. of parent [%] other_mono 116722 other_mono_33 other_mono_59 other_mono_85	DO population	both	33-85 wks	N=257

Project1140:233	Project1140	immune cell quantification	(none)	single cells/viable cells/CD11b+/monocytes/resident monocytes,freq. of parent [%] resid_mono 116725 resid_mono_33 resid_mono_59 resid_mono_85	DO population	both	33-85 wks	N=257

Project1140:236	Project1140	immune cell quantification	(none)	single cells,freq. of parent_t [n] single_t 116728 single_t33 single_t59 single_t85	DO population	both	33-85 wks	N=256

Project1140:239	Project1140	immune cell quantification	(none)	single cells/viable cells,freq. of parent_t [%] viable_t 116731 viable_t33 viable_t59 viable_t85	DO population	both	33-85 wks	N=256

Project1140:242	Project1140	immune cell quantification	(none)	single cells/viable cells/lymphocytes,freq. of parent [%] lymph 116734 lymph_33 lymph_59 lymph_85	DO population	both	33-85 wks	N=256

Project1140:245	Project1140	immune cell quantification	(none)	single cells/viable cells/lymphocytes/B cells,freq. of parent [%] b_cells 116737 b_cells_33 b_cells_59 b_cells_85	DO population	both	33-85 wks	N=256

Project1140:248	Project1140	immune cell quantification	(none)	single cells/viable cells/lymphocytes/B cells,freq. of,viable cells [%] b_cells_perc 116740 b_cells_perc_33 b_cells_perc_59 b_cells_perc_85	DO population	both	33-85 wks	N=256

Project1140:251	Project1140	immune cell quantification	(none)	single cells/viable cells/lymphocytes/B cells/CD62l+,freq. of parent [%] cd62l_b 116743 cd62l_b_33 cd62l_b_59 cd62l_b_85	DO population	both	33-85 wks	N=256

Project1140:254	Project1140	immune cell quantification	(none)	single cells/viable cells/lymphocytes/CD4 T cells,freq. of parent [%] cd4_t 116746 cd4_t_33 cd4_t_59 cd4_t_85	DO population	both	33-85 wks	N=256

Project1140:257	Project1140	immune cell quantification	(none)	single cells/viable cells/lymphocytes/CD4 T cells,freq. of,viable cells [%] cd4_t_perc 116749 cd4_t_perc_33 cd4_t_perc_59 cd4_t_perc_85	DO population	both	33-85 wks	N=256

Project1140:260	Project1140	immune cell quantification	(none)	single cells/viable cells/lymphocytes/CD4 T cells/q1: CD62l-, CD44+,freq. of parent [%] cd4_emt 116752 cd4_emt_33 cd4_emt_59 cd4_emt_85	DO population	both	33-85 wks	N=256

Project1140:263	Project1140	immune cell quantification	(none)	single cells/viable cells/lymphocytes/CD4 T cells/q2: CD62l+, CD44+,freq. of parent [%] cd4_cmt 116755 cd4_cmt_33 cd4_cmt_59 cd4_cmt_85	DO population	both	33-85 wks	N=256

Project1140:266	Project1140	immune cell quantification	(none)	single cells/viable cells/lymphocytes/CD4 T cells/q3: CD62l+, CD44-,freq. of parent [%] cd4_nt 116758 cd4_nt_33 cd4_nt_59 cd4_nt_85	DO population	both	33-85 wks	N=256

Project1140:269	Project1140	immune cell quantification	(none)	single cells/viable cells/lymphocytes/CD4 T cells/q4: CD62l-, CD44-,freq. of parent [%] cd4_et 116761 cd4_et_33 cd4_et_59 cd4_et_85	DO population	both	33-85 wks	N=256

Project1140:272	Project1140	immune cell quantification	(none)	single cells/viable cells/lymphocytes/CD8 T cells/q2: CD62l+, CD44+,freq. of parent [%] cd8_cmt 116770 cd8_cmt_33 cd8_cmt_59 cd8_cmt_85	DO population	both	33-85 wks	N=256

Project1140:275	Project1140	immune cell quantification	(none)	single cells/viable cells/lymphocytes/CD8 T cells,freq. of parent [%] cd8_t 116764 cd8_t_33 cd8_t_59 cd8_t_85	DO population	both	33-85 wks	N=256

Project1140:278	Project1140	immune cell quantification	(none)	single cells/viable cells/lymphocytes/CD8 T cells/q1: CD62l-, CD44+,freq. of parent [%] cd8_emt 116767 cd8_emt_33 cd8_emt_59 cd8_emt_85	DO population	both	33-85 wks	N=256

Project1140:281	Project1140	immune cell quantification	(none)	single cells/viable cells/lymphocytes/CD8 T cells/q3: CD62l+, CD44-,freq. of parent [%] cd8_nt 116773 cd8_nt_33 cd8_nt_59 cd8_nt_85	DO population	both	33-85 wks	N=256

Project1140:284	Project1140	immune cell quantification	(none)	single cells/viable cells/lymphocytes/CD8 T cells/q4: CD62l-, CD44-,freq. of parent [%] cd8_et 116776 cd8_et_33 cd8_et_59 cd8_et_85	DO population	both	33-85 wks	N=256

Project1140:287	Project1140	immune cell quantification	(none)	single cells/viable cells/lymphocytes/NK cells,freq. of parent [%] nk 116779 nk_33 nk_59 nk_85	DO population	both	33-85 wks	N=256

Project1140:290	Project1140	immune cell quantification	(none)	single cells/viable cells/lymphocytes/NK cells,freq. of,viable cells [%] nk_perc 116782 nk_perc_33 nk_perc_59 nk_perc_85	DO population	both	33-85 wks	N=256

Project1140:293	Project1140	immune cell quantification	(none)	single cells/viable cells/lymphocytes/NKG2A-C-E+ T cells,freq. of parent [%] nkg2_t 116785 nkg2_t_33 nkg2_t_59 nkg2_t_85	DO population	both	33-85 wks	N=256

Project1140:296	Project1140	immune cell quantification	(none)	single cells/viable cells/lymphocytes/NKG2A-C-E+ t cells/CD4+,freq. of parent [%] nkg2_cd4_t 116791 nkg2_cd4_t_33 nkg2_cd4_t_59 nkg2_cd4_t_85	DO population	both	33-85 wks	N=256

Project1140:299	Project1140	immune cell quantification	(none)	single cells/viable cells/lymphocytes/NKG2A-C-E+ T cells,freq. of,viable cells [%] nkg2_t_perc 116788 nkg2_t_perc_33 nkg2_t_perc_59 nkg2_t_perc_85	DO population	both	33-85 wks	N=256

Project1140:302	Project1140	None	(none)	single cells/viable cells/lymphocytes/NKG2A-C-E+ T cells/CD8+,freq. of parent [%] nkg2_cd8_t 116794 nkg2_cd8_t_33 nkg2_cd8_t_59 nkg2_cd8_t_85	DO population	both	33-85 wks	N=256

Project1140:305	Project1140	immune cell quantification	(none)	single cells/viable cells/lymphocytes/NKG2A-C-E+ T cells/DN,freq. of parent [%] nkg2_dn_t 116797 nkg2_dn_t_33 nkg2_dn_t_59 nkg2_dn_t_85	DO population	both	33-85 wks	N=256

Project1140:308	Project1140	body size and weight	(none)	tail length [cm] Tail_Length 116800	DO population	f	varies	N=300

Project1140:311	Project1140	colony observation	(none)	lifespan [days] lifespan 118151	DO population	both	varies	N=300

Project1140: Shock Center Longitudinal Aging Study (None) [Pending]

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