Peters5: Hematologic data for F2 progeny of C3H/HeJ+/wan x CAST/EiJ (2004)

Peters LL, Swearingen RA, Andersen SG, Gwynn B, Lambert AJ, Li R, Lux SE, Churchill GA. Identification of quantitative trait loci that modify the severity of hereditary spherocytosis in wan, a new mouse model of band-3 deficiency. Blood. 2004 Apr 15;103(8):3233-40. Epub 2003 Dec 30.   PubMed 15070709  


       
An intercross between C3H/HeJ+/wan x CAST/EiJ inbred mouse strains was generated to identify QTLs that modify the hereditary spherocytosis (HS) phenotype. RBC count, hematocrit, hemoglobin, mean corpuscular volume, and mean corpuscular hemoglobin content, were measured in newborn F2 mice with C3H wan mutation (pups die within 72h of birth). For detailed protocols see Peters et al 2004.

Note on studied population: C3H/HeJ+/wan x CAST/EiJ F2 progeny

Procedures conducted:
• study archive  Complete blood count measures on fetuses, newborns.

Peters5 downloads
QTL projects have several available downloads.
Use the QTL Data Downloads button near the bottom of this page.
Investigators Luanne L Peters       The Jackson Laboratory,  Bar Harbor, ME
Participants Swearingen RA, Andersen SG, Gwynn B, Lambert AJ, Li R, Lux SE, Churchill GA
ContactLuanne L Peters     Luanne.Peters@jax.org
Affiliated CenterQTL Archive
AcknowledgementsFunding provided by NIH HL64885, HL32262, DK34083, RR01183, CA34196; and The March of Dimes
Project type QTL Archive data set
MPD identifiersPeters5     MPD:147
Data changelog No updates/corrections.       Initial release date: 01/2008.
QTL data set parameters:
Progenitor strains C3H/HeJ+/wan     CAST/EiJ    
Cross typeF2 intercross
Population size 97 ♀     86 ♂
Agefetuses, newborns


Measured phenotypes:       To access these data use the QTL Data Downloads button at bottom of page.

Associated genomic features
MGI-curated QTL / genomic features that have been associated with this data set:
Hsm1  


Project / data set:   Peters5     a.k.a. Peters_2004
Excel file:   Data_Description_C3HxCAST_Peters2004.xlsx
CSV file:   Peters2004_C3HxCAST_B37_Data.csv
Readme / text file:   readme_Peters2004.txt
QC plots, figures, etc.:   QCReport_Peters2004.pdf