MPD: Data set: Mogil1

References (chronological)

1. Mogil JS, Wilson SG, Bon K, Lee SE, Chung K, Raber P, Pieper JO, Hain HS, Belknap JK, Hubert L, Elmer GI, Chung JM, Devor M. Heritability of nociception I: responses of 11 inbred mouse strains on 12 measures of nociception. Pain. 1999 Mar;80(1-2):67-82. PubMed 10204719

2. Mogil JS, Wilson SG, Bon K, Lee SE, Chung K, Raber P, Pieper JO, Hain HS, Belknap JK, Hubert L, Elmer GI, Chung JM, Devor M. Heritability of nociception II. 'Types' of nociception revealed by genetic correlation analysis. Pain. 1999 Mar;80(1-2):83-93. PubMed 10204720

3. Lariviere WR, Wilson SG, Laughlin TM, Kokayeff A, West EE, Adhikari SM, Wan Y, Mogil JS. Heritability of nociception. III. Genetic relationships among commonly used assays of nociception and hypersensitivity. Pain. 2002 May;97(1-2):75-86. PubMed 12031781

Notes
For each strain/sex/measurement the following summary data were submitted: mean measurement value, N (usually a range such as "6-8"), and standard error of the measurement value.

Dec 2008: In order to use these data more effectively with MPD tools, where N was supplied as a range the lower N value is retained in the MPD database.

Mogil1 downloads
• Download Mogil1 strain means, SD, N, etc. one row per strain/sex/measure

Investigators	Jeffrey S Mogil McGill University, Montreal, Quebec CANADA Marshall Devor Hebrew University of Jerusalem, Jerusalem ISRAEL William R Lariviere University of Pittsburgh School of Medicine, Pittsburgh, PA
Participants	Wilson SG, Bon K, Lee SE, Chung K, Raber P, Pieper JO, Hain HS, Belknap JK, Hubert L, Elmer GI, Chung JM, Laughlin TM, Kokayeff A, West EE, Adhikari SM, Wan Y
Contact	Jeffrey S Mogil jeffrey.mogil@mcgill.ca Lab web site
Acknowledgements	Funding provided by NIH DA11394, DA11888, NS35057, NS31680, NS11255, DE12735; and by Fritz Thyssen Stiftung Foundation and the Hebrew University Center for Research on Pain, Fonds pour la Formation de Chercheurs et l'Aide a la Recherche of Quebec.
Project type	Phenotype strain survey data set
MPD identifiers	Mogil1 MPD:22
Data changelog	2 updates/corrections. Initial release date: 02/2001.
Formatted citation	Click above to copy-paste the entire citation for this MPD web page.

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)
Mogil1:1	Mogil1	nociception assay	(none)	latency of nociceptive response, (53°C) hot plate test [s] HP 2201	inbred	11	m	6-18wks	N=8

Mogil1:2	Mogil1	nociception assay	(none)	latency of heated hindpaw withdrawal, Hargreaves test [s] HT 2202	inbred	11	m	6-18wks	N=6

Mogil1:3	Mogil1	nociception assay	(none)	latency of tail withdrawal, 49°C heat stimulation [s] TW_HOT1 2203	inbred	11	m	6-18wks	N=10

Mogil1:4	Mogil1	nociception assay	(none)	median 50% foot withdrawal threshold, Von Frey test [mN] VF 2204	inbred	11	m	6-18wks	N=7

Mogil1:5	Mogil1	nociception assay	(none)	number of abdominal constrictions induced with acetic acid (i.p.), 20 min [n] AC_AA 2205	inbred	11	m	6-18wks	N=6

Mogil1:6	Mogil1	nociception assay	(none)	number of abdominal constrictions induced with magnesium sulfate (i.p.), 5 min [n] AC_MS 2206	inbred	11	m	6-18wks	N=6

Mogil1:7	Mogil1	nociception assay	(none)	percent hypersensitivity threshold to carrageenan-induced thermal hyperalgesia, treated and heated hindpaw withdrawal [%] CAR_HT 2207	inbred	11	m	6-18wks	N=6

Mogil1:8	Mogil1	nociception assay	(none)	duration of nociceptive response to acute inflammation (early phase), 0-10 min post-formalin (s.q.) injection [s] F_early 2208	inbred	11	m	6-18wks	N=7

Mogil1:9	Mogil1	nociception assay	(none)	duration of nociceptive response to subacute/chronic inflammation (late phase), 10-60 min post-formalin (s.q.) injection [s] F_late 2209	inbred	11	m	6-18wks	N=7

Mogil1:10	Mogil1	nociception assay	(none)	autotomy (neuropathy) score (1-11) following hindlimb denervation [score] AUT 2210	inbred	11	m	6-18wks	N=9

Mogil1:11	Mogil1	nociception assay	(none)	percent hypersensitivity threshold to Hargreaves test following peripheral nerve injury (PNI) [%] PNI_HT 2211	inbred	11	m	6-18wks	N=6

Mogil1:12	Mogil1	nociception assay	(none)	median 50% foot withdrawal hypersensitivity threshold to von Frey test following peripheral nerve injury (PNI) [mN] PNI_VF 2212	inbred	11	m	6-18wks	N=7

Mogil1:20	Mogil1	nociception assay	(none)	duration of nociceptive response to capsaicin [s] CAP 2220	inbred	12	m	6-18wks	N=5

Mogil1:21	Mogil1	nociception assay	(none)	duration of nociceptive response to bee venom [s] BV 2221	inbred	12	m	6-18wks	N=5

Mogil1:22	Mogil1	nociception assay	(none)	latency of nociception to heated tail following hindleg acupuncture needles stimulation (analgesia), tail flick test [s] TF 2222	inbred	10	m	6-18wks	N=21

Mogil1:23	Mogil1	nociception assay	(none)	latency of tail withdrawal, 47°C heat stimulation [s] TW_HOT2 2223	inbred	12	m	6-18wks	N=5

Mogil1:24	Mogil1	nociception assay	(none)	latency of tail withdrawal, -15°C cold stimulation [s] TW_COLD 2224	inbred	12	m	6-18wks	N=5

Mogil1:25	Mogil1	nociception assay	(none)	percent hypersensitivity threshold to capsaicin-induced thermal hyperalgesia, tail withdrawal at 47°C [%] CAP_TW 2225	inbred	12	m	6-18wks	N=5

Mogil1:26	Mogil1	nociception assay	(none)	percent hypersensitivity threshold to bee venom-induced thermal hyperalgesia (ipsilateral), treated and heated hindpaw withdrawal [%] BV_HT 2226	inbred	12	m	6-18wks	N=5

Mogil1:27	Mogil1	nociception assay	(none)	percent hypersensitivity threshold to bee venom-induced thermal hyperalgesia (contralateral), untreated and heated hindpaw withdrawal [%] BV_HT_CON 2227	inbred	12	m	6-18wks	N=5

Mogil1:28	Mogil1	nociception assay	(none)	latency of nociception to pinched tail [s] TC 2228	inbred	12	m	6-18wks	N=7

Mogil1:29	Mogil1	nociception assay	(none)	percent hypersensitivity threshold to mechanical stimulation following dynorphin treatment, von Frey test [%] DYN_VF 2229	inbred	7	m	6-18wks	N=4

Mogil1: Investigation of basal nociception in males of 12 inbred strains of mice (2002)