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JaxKOMP-EAP project protocol

Multisystem phenotyping of KOMP strains and C57BL/6NJ controls, early adult mice   (2021)

JAX KOMP Phenotyping Center
With:






The IMPC Jax KOMP phenotyping pipeline was utilized.
Observed age of test

Grip strength 8 wks
Open field 8 wks
SHIRPA and dysmorphology 9 wks
Y-maze (no published protocol at this time) 9 wks
Hole-board exploration 10 wks
Light-dark test 10 wks
Auditory brain stem response 10 wks
Acoustic startle and pre-pulse inhibition 10 wks
Rotarod 11 wks
Electrocardiogram 11 wks
Tail suspension test 11 wks
Intraperitoneal glucose tolerance test 12 wks
Urinalysis 13 wks
Plasma chemistry 13 wks
X-ray 14 wks
Body composition / DXA 14 wks
Eye morphology 14 wks
Sleep / wake 15 wks
Electroretinography   ...or...   Electroretinography 2 16 wks
Clinical chemistry 17 wks
Electroconvulsive threshold testing 17 wks
Heart weight 18 wks
Hematology 18 wks
Insulin blood level 18 wks