JaxCC1 project protocol

Multisystem phenotyping of 18 Collaborative Cross strains   (2018)

The Jackson Laboratory






The IMPC Jax KOMP phenotyping pipeline was utilized.
Observed age of test

Open field test 7 - 9 wks
Grip strength 7 - 9 wks
Hole board test 8 - 10 wks
Light-dark box 8 - 10 wks
Acoustic startle and pre-pulse inhibition 9 - 11 wks
Electrocardiogram (ECG) 10 - 12 wks
Tail suspension test 10 - 12 wks
Rotarod 10 - 12 wks
Urinalysis 12 - 13 wks
DXA / body composition 13 - 15 wks
Clinical chemistry (metabolic panel, lipid profile) 17 - 19 wks
Insulin blood level 17 - 19 wks
Hematology / complete blood count 17 - 19 wks
Heart weight 17 - 19 wks