Acclimation and testing periods
Vendor Male mice from the hybrid HMDP panel were purchased from the The Jackson Laboratory (JAX®, Bar Harbor, Maine) Ages Mice were between 6 and 10 wks of age and aged until 16 wks to ensure adequate acclimatization to a common environment at the University of California at Los Angeles (UCLA) Gonda Research Building vivarium Feed Mice were maintained on a chow diet (Ralston-Purina Co, St. Louis, Mo) Water Mice were provided ad libitum access to water HousingMice were housed in groups of 3-4 per cage Photoperiod 12-h light: 12-h dark cycle Regulatory compliance All procedures were performed under NIH Care and Use Guidelines and were approved by the UCLA Animal Research Committee