MPD: Data set: Beamer1

Beamer1: Bone mineral density in F2 progeny from a C57BL/6J x CAST/EiJ intercross (1999)

Beamer WG, Shultz KL, Churchill GA, Frankel WN, Baylink DJ, Rosen CJ, Donahue LR. Quantitative trait loci for bone density in C57BL/6J and CAST/EiJ inbred mice. Mamm Genome. 1999 Nov;10(11):1043-9. PubMed 10556421

Ackert-Bicknell CL, Karasik D, Li Q, Smith RV, Hsu YH, Churchill GA, Paigen BJ, Tsaih SW. Mouse BMD quantitative trait loci show improved concordance with human genome-wide association loci when recalculated on a new, common mouse genetic map. J Bone Miner Res. 2010 Aug;25(8):1808-20. PubMed 20200990

Beamer1 downloads
QTL projects have several available downloads.
Use the QTL Data Downloads button near the bottom of this page.

Ontology terms mapped to Beamer1 measures:

Investigators	Wesley G Beamer The Jackson Laboratory, Bar Harbor, ME
Participants	Shultz KL, Frankel WN, Baylink DJ, Rosen CJ, Donahue LR, Ackert-Bicknell CL, Karasik D, Li Q, Smith RV, Hsu YH, Churchill GA, Paigen BJ, Tsaih SW
Contact	Wesley G Beamer wgb@jax.org
Affiliated Center	QTL Archive
Acknowledgements	Funding provided by NIH AR43618, RR08911, CA34196; US Army (DAMA17-94-J-4016) and the SD Bechtel Foundation
Project type	QTL Archive data set
MPD identifiers	Beamer1 MPD:105
Data changelog	No updates/corrections. Initial release date: 01/2008.

An intercross of C57BL/6J and CAST/EiJ was generated to identify QTLs for bone mineral density. F2 females were tested for femoral density. For detailed protocols see Beamer et al 1999.

QTL data set parameters:

Progenitor strains	C57BL/6J CAST/EiJ
Cross direction notation	(B6xCAST) F1 x (B6xCAST) F1
Cross type	F2 intercross
Population size	711 ♀ 0 ♂
Age	20wks

Measured phenotypes: To access these data use the QTL Data Downloads button at bottom of page.

Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	Sex	Age	Sample Size (Avg)
Beamer1	computed tomography	(none)	femur, average bone volume (total, mid diaphysis) [g/cm³] femur_mid_cort_vol 10501	QTL population	f	20wks	N=711

Beamer1	computed tomography	(none)	femur, average cortical bone volume (mid-diaphysis) [g/cm³] femur_mid_tot_vol 10502	QTL population	f	20wks	N=711

Associated genomic features

MGI-curated QTL / genomic features that have been associated with this data set:
Bmd1 Bmd2 Bmd3 Bmd4

Project / data set: Beamer1 a.k.a. Beamer_1999
Excel file: ._Data_Description_B6xCAST_Beamer1999.xlsx
Excel file: Data_Description_B6xCAST_Beamer1999.xlsx
CSV file: ._Beamer1999_B6xCAST_B37_Data.csv
CSV file: Beamer1999_B6xCAST_B37_Data.csv
Readme / text file: ._readme.txt
Readme / text file: readme_Beamer1999.txt
QC plots, figures, etc.: QCReport_Beamer1999.pdf