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      • abnormal solitary pulmonary neuroendocrine cell morphology

    • decreased solitary pulmonary neuroendocrine cell number   MP:0010916   (0)
    Definition: decreased number of the specialized non-ciliated, round- to oval-shaped epithelial cells found as solitary cells in the nasal respiratory epithelium and the mucosa of the larynx, trachea and bronchi up to the terminal bronchioles; PNECs are the first cell type to differentiate during early fetal lung development, produce amine (e.g. serotonin, 5-HT) and peptides (e.g. bombesin, calcitonin) with growth factor-like properties, and appear to be involved in processes ranging from lung development and respiratory physiology to repair, disease and carcinogenesis [https://orcid.org/0000-0002-6490-7723]; xref: CL:0002066; xref: FMA:14118;   [MGI annotations / genotypes]
      (No descendants that are mapped to MPD data)



    VT:0010916 (blood gastric inhibitory polypeptide amount) is numbered similarly to MP:0010916 but is over in the VT ontology (semantics may or may not be similar).

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