MPD: Project measures / variables set: Poon1 RMS

Project measures / variables set: Poon1 RMS

ID, description, units	MPD:47501 RMS BrdU+ cells of rostral migratory stream [n/mm]
Measures	• 3mo • 12mo • 18mo
Data set, strains	Poon1 inbred 9 strains sex: both
Procedure	histopathology
Comparison	aging-study, multiple cohorts
Ontology mappings	VT:0010536 rostral migratory stream morphology trait MA:0000817 brain subventricular zone MP:0004279 abnormal rostral migratory stream morphology

Values Means Δ Means Z-scores

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Poon1 - BrdU+ cells of rostral migratory stream

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
age	2	38397.2098	19198.6049	171.0723	< 0.0001
sex	1	254.4427	254.4427	2.2673	0.1386
strain	4	1523.0413	380.7603	3.3928	0.0158
age:sex	2	66.029	33.0145	0.2942	0.7464
age:strain	8	2593.9457	324.2432	2.8892	0.0102
sex:strain	4	1181.4896	295.3724	2.632	0.0453
age:sex:strain	8	480.2831	60.0354	0.535	0.8244
Residuals	49	5499.0306	112.2251

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Poon1	47501	histopathology	(none)	BrdU+ cells of rostral migratory stream [n/mm] at age 3mo RMS_M03	inbred	9	both
Poon1	47502	histopathology	(none)	BrdU+ cells of rostral migratory stream [n/mm] at age 12mo RMS_M12	inbred	9	both	52wks
Poon1	47503	histopathology	(none)	BrdU+ cells of rostral migratory stream [n/mm] at age 18mo RMS_M18	inbred	9	both	78wks