MPD: Project measures / variables set: Gould3 jumping

Project measures / variables set: Gould3 jumping

ID, description, units	MPD:47311 jumping withdrawal study group, number of jumping episodes, 20 min test [n] nicotine study
Measures	• control • nicotine dose (mg) • 3 • 6.3 • 12
Data set, strains	Gould3 inbred 8 strains sex: m age: 8-12wks
Procedure	behavior observation
Comparison	control group vs. multiple treatment / dosage groups
Ontology mappings	VT:0003492 involuntary movement trait VT:0010716 anxiety-related behavior trait VT:0010721 response to nicotine trait VT:0010722 withdrawal response to addictive substance trait MP:0001362 abnormal anxiety-related response MP:0003492 abnormal involuntary movement MP:0009774 abnormal behavioral withdrawal response MP:0020160 abnormal behavioral response to nicotine

Values Means Δ Means Z-scores

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Gould3 - withdrawal study group, number of jumping episodes, 20 min test

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
dose	3	40.3398	13.4466	1.4759	0.221
strain	7	1423.8972	203.4139	22.3272	< 0.0001
dose:strain	21	258.3995	12.3047	1.3506	0.1412
Residuals	313	2851.6127	9.1106

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Gould3	47311	behavior observation	nicotine	withdrawal study group, number of jumping episodes, 20 min test [n] control jumping_0	inbred	8	m	8-12wks
Gould3	47312	behavior observation	nicotine	withdrawal study group, number of jumping episodes, 20 min test [n] dose: 3 mg jumping_3	inbred	8	m	8-12wks
Gould3	47313	behavior observation	nicotine	withdrawal study group, number of jumping episodes, 20 min test [n] dose: 6.3 mg jumping_6	inbred	8	m	8-12wks
Gould3	47314	behavior observation	nicotine	withdrawal study group, number of jumping episodes, 20 min test [n] dose: 12 mg jumping_12	inbred	8	m	8-12wks