Project measures / variables set:   Gould2   cotinine

ID, description, units MPD:47105   cotinine   plasma cotinine   [ng/mL]  
nicotine study
Measures
• acute 0.09mg dose    • chronic 6.3mg dose
Data set, strains Gould2   inbred   8 strains     sex: m     age: 8-12wks
Procedure drug and metabolite quantification
Comparisonmultiple dosage cohorts but no control group
Ontology mappings

  SIDE-BY-SIDE STRAIN CURVES
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  OVERLAPPING STRAIN CURVES
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Gould2 - plasma cotinine




  ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary     

Factor DF Sum of squares Mean sum of squares F value p-value (Pr>F)
group 1 240027.6595 240027.6595 1001.6465 < 0.0001
strain 7 87940.9337 12562.9905 52.4259 < 0.0001
group:strain 7 66740.4303 9534.3472 39.7873 < 0.0001
Residuals 140 33548.6339 239.6331

Q-Q normality assessment based on residuals

  


  INDIVIDUAL MEASURES
ProjectIDTreatmentMeasure / Variable Description PanelStrains
tested
SexAge
Gould2 47105 drug and metabolite quantification nicotine plasma cotinine   [ng/mL]   acute 0.09mg dose  cotinine_acu inbred 8 m
Gould2 47106 drug and metabolite quantification nicotine plasma cotinine   [ng/mL]   chronic 6.3mg dose  cotinine_chr inbred 8 m