MPD: Project measures / variables set: Crowley1 latency

Project measures / variables set: Crowley1 latency

ID, description, units	MPD:39407 latency latency to move four paws, extrapyramidal side effects [s] haloperidol study
Measures	• day: • 0 • 3 • 7 • 30 • 60 • 120
Data set, strains	Crowley1 inbred w/CC8 27 strains sex: m age: 9-28wks
Procedure	inclined screen test
Comparison	timecourse, same cohort
Ontology mappings	VT:0001516 motor coordination/balance trait VT:0010487 response to xenobiotic stimulus trait MP:0001516 abnormal motor coordination/balance MP:0009745 abnormal behavioral response to xenobiotic

Values Means Δ Means Z-scores

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Crowley1 - latency to move four paws, extrapyramidal side effects

ANOVA Summary "within" = Within error "between" = Between Error (Animal ID)

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
between strain	25	2242159.7754	89686.391	44.8145	< 0.0001
between Residuals	122	244156.0478	2001.2791
within day	5	289656.9381	57931.3876	50.259	< 0.0001
within day:strain	125	792096.8089	6336.7745	5.4975	< 0.0001
within Residuals	610	703120.753	1152.657

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Crowley1	39407	inclined screen test	haloperidol	latency to move four paws, extrapyramidal side effects [s] on day 0 latency_d0	inbred w/CC8	27	m	9-28wks
Crowley1	39408	inclined screen test	haloperidol	latency to move four paws, extrapyramidal side effects [s] on day 3 latency_d3	inbred w/CC8	27	m	9-28wks
Crowley1	39409	inclined screen test	haloperidol	latency to move four paws, extrapyramidal side effects [s] on day 7 latency_d7	inbred w/CC8	27	m	9-28wks
Crowley1	39410	inclined screen test	haloperidol	latency to move four paws, extrapyramidal side effects [s] on day 30 latency_d30	inbred w/CC8	27	m	9-28wks
Crowley1	39411	inclined screen test	haloperidol	latency to move four paws, extrapyramidal side effects [s] on day 60 latency_d60	inbred w/CC8	27	m	9-28wks
Crowley1	39445	inclined screen test	haloperidol	latency to move four paws, extrapyramidal side effects [s] on day 120 latency_d120	inbred w/CC8	26	m	9-28wks