MPD: Project measures / variables set: Bennett3 BEC

Project measures / variables set: Bennett3 BEC

ID, description, units	MPD:37501 BEC blood ethanol concentration (BEC) [mg/mL] ethanol study
Measures	• first loss of balance (ataxia) • first regain of balance • second regain of balance
Data set, strains	Bennett3 ILSXISS w/par 74 strains sex: both age: 8-14wks
Procedure	alcohol quantification
Comparison	timecourse, same cohort
Ontology mappings	VT:0015078 blood homeostasis trait VT:0005443 ethanol metabolism trait MA:0000059 blood MP:0005443 abnormal ethanol metabolism

Values Means Δ Means Z-scores

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Bennett3 - blood ethanol concentration (BEC)

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary "within" = Within error "between" = Between Error (Animal ID)

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
between sex	1	14.2674	14.2674	42.0721	< 0.0001
between strain	64	151.5216	2.3675	6.9814	< 0.0001
between sex:strain	64	45.5806	0.7122	2.1001	< 0.0001
between Residuals	542	183.8022	0.3391
within group	2	106.1285	53.0643	387.8532	< 0.0001
within group:sex	2	2.1843	1.0921	7.9826	0.0004
within group:strain	128	67.9155	0.5306	3.8781	< 0.0001
within group:sex:strain	128	28.8202	0.2252	1.6457	< 0.0001
within Residuals	1084	148.3078	0.1368

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Bennett3	37501	alcohol quantification	ethanol	blood ethanol concentration (BEC) [mg/mL] at first loss of balance (ataxia) BEC_0	ILSXISS w/par	74	both	8-14wks
Bennett3	37502	alcohol quantification	ethanol	blood ethanol concentration (BEC) [mg/mL] at first regain of balance BEC_1	ILSXISS w/par	74	both	8-14wks
Bennett3	37503	alcohol quantification	ethanol	blood ethanol concentration (BEC) [mg/mL] at second regain of balance BEC_2	ILSXISS w/par	74	both	8-14wks