MPD: Project measures / variables set: Gould1 immob

Project measures / variables set: Gould1 immob

ID, description, units	MPD:37401 immob duration of immobility [s] lithium study
Measures	• lithium dose [mg/kg]: • 0(saline) • 200 • 300 • 400
Data set, strains	Gould1 inbred 11 strains sex: m age: 7-8wks
Procedure	forced swim test
Comparison	control group vs. multiple treatment / dosage groups
Ontology mappings	VT:0010487 response to xenobiotic stimulus trait VT:0015015 depression-related behavior trait MP:0003360 abnormal depression-related behavior MP:0009745 abnormal behavioral response to xenobiotic

Values Means Δ Means Z-scores

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Gould1 - duration of immobility

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
dose	3	55612.8837	18537.6279	18.8315	< 0.0001
strain	10	1729853.7354	172985.3735	175.728	< 0.0001
dose:strain	30	108417.4009	3613.9134	3.6712	< 0.0001
Residuals	289	284489.5476	984.3929

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Gould1	37401	forced swim test	lithium	duration of immobility [s] dose: 0(saline) mg/kg immob	inbred	11	m	7-8wks
Gould1	37402	forced swim test	lithium	duration of immobility [s] dose: 200 mg/kg immob200	inbred	11	m	7-8wks
Gould1	37403	forced swim test	lithium	duration of immobility [s] dose: 300 mg/kg immob300	inbred	11	m	7-8wks
Gould1	37404	forced swim test	lithium	duration of immobility [s] dose: 400 mg/kg immob400	inbred	11	m	7-8wks