MPD: Project measures / variables set: Rusyn2 BUN

Project measures / variables set: Rusyn2 BUN_tce

ID, description, units	MPD:36137 BUN_tce blood urea nitrogen (serum BUN), treated group [mg/dL] trichloroethylene study
Measures	• time: 2h • 8h • 24h
Data set, strains	Rusyn2 inbred 16 strains sex: m age: 7wks
Procedure	metabolic panel
Comparison	timecourse but different cohorts
Ontology mappings	VT:0010487 response to xenobiotic stimulus trait VT:0005265 blood urea nitrogen amount MA:0002502 serum MP:0005265 abnormal blood urea nitrogen level MP:0008872 abnormal physiological response to xenobiotic

Values Means Δ Means Z-scores

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Rusyn2 - blood urea nitrogen (serum BUN), treated group

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
time	2	20.288	10.144	0.6672	0.5157
strain	14	1127.1698	80.5121	5.2954	< 0.0001
time:strain	28	849.4352	30.337	1.9953	0.0078
Residuals	89	1353.1667	15.2041

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Rusyn2	36137	metabolic panel	trichloroethylene	blood urea nitrogen (serum BUN), treated group [mg/dL] 2h after treatment BUN_2_tce	inbred	15	m	7wks
Rusyn2	36138	metabolic panel	trichloroethylene	blood urea nitrogen (serum BUN), treated group [mg/dL] 8h after treatment BUN_8_tce	inbred	16	m	7wks
Rusyn2	36139	metabolic panel	trichloroethylene	blood urea nitrogen (serum BUN), treated group [mg/dL] 24h after treatment BUN_24_tce	inbred	15	m	7wks