MPD: Project measures / variables set: Yuan3 HDL

Project measures / variables set: Yuan3 HDL

ID, description, units	MPD:24471 HDL HDL cholesterol (plasma HDL) [mg/dL]
Measures	• 6mo • 12mo • 18mo
Data set, strains	Yuan3 inbred 32 strains sex: both
Procedure	lipid profile
Comparison	timecourse, same cohort (aging study)
Ontology mappings	VT:0000184 blood HDL cholesterol amount MA:0002501 plasma MP:0000184 abnormal circulating HDL cholesterol level

Values Means Δ Means Z-scores

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Yuan3 - HDL cholesterol (plasma HDL)

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary "within" = Within error "between" = Between Error (Animal ID)

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
between sex	1	11881.6354	11881.6354	26.1862	< 0.0001
between strain	3	73811.491	24603.8303	54.2249	< 0.0001
between sex:strain	3	2170.9527	723.6509	1.5949	0.2071
between Residuals	37	16788.2649	453.7369
within age	2	3140.7453	1570.3727	7.2935	0.0013
within age:sex	2	739.7735	369.8868	1.7179	0.1865
within age:strain	6	9359.5054	1559.9176	7.2449	< 0.0001
within age:sex:strain	6	2699.2927	449.8821	2.0894	0.0645
within Residuals	74	15933.0764	215.3118

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Yuan3	24471	lipid profile	(none)	HDL cholesterol (plasma HDL) [mg/dL] at age 6mo HDL_M06	inbred	31	both	26wks
Yuan3	24472	lipid profile	(none)	HDL cholesterol (plasma HDL) [mg/dL] at age 12mo HDL_M12	inbred	31	both	52wks
Yuan3	24473	lipid profile	(none)	HDL cholesterol (plasma HDL) [mg/dL] at age 18mo HDL_M18	inbred	29	both	78wks