MPD: Project measures / variables set: Jaxpheno6 pct

Project measures / variables set: Jaxpheno6 pct_CD8

ID, description, units	MPD:23103 pct_CD8 splenic CD8 T cells (percentage of total viable cells) [%]
Measures	• 8wks • 16wks
Data set, strains	Jaxpheno6 inbred 11 strains sex: both
Procedure	immune cell quantification
Comparison	multiple cohorts measured at two age timepoints
Ontology mappings	VT:0000689 spleen morphology trait VT:0008077 CD8-positive T cell quantity MA:0000141 spleen MP:0008073 abnormal CD4-positive, alpha beta T cell number

Values Means Δ Means Z-scores

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Jaxpheno6 - splenic CD8 T cells (percentage of total viable cells)

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
age	1	14.8718	14.8718	6.7489	0.0101
sex	1	11.26	11.26	5.1098	0.0249
strain	5	2312.9662	462.5932	209.9266	< 0.0001
age:sex	1	0.3714	0.3714	0.1685	0.6819
age:strain	5	115.6836	23.1367	10.4995	< 0.0001
sex:strain	5	59.2989	11.8598	5.382	0.0001
age:sex:strain	5	6.6273	1.3255	0.6015	0.6988
Residuals	189	416.4796	2.2036

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Jaxpheno6	23103	immune cell quantification	(none)	splenic CD8 T cells (percentage of total viable cells) [%] at age age 8wks pct_CD8_8	inbred	11	both	8wks
Jaxpheno6	23104	immune cell quantification	(none)	splenic CD8 T cells (percentage of total viable cells) [%] at age age 16wks pct_CD8_16	inbred	8	both	16wks