MPD: Project measures / variables set: Gershenfeld1 OFTactivity

Project measures / variables set: Gershenfeld1 OFTactivity

ID, description, units	MPD:16212 OFTactivity distance traveled in 5 min [cm] imipramine study
Measures	• baseline • imipramine 30mg/kg
Data set, strains	Gershenfeld1 inbred 12 strains sex: m age: 5-10wks
Procedure	open field test
Comparison	control group vs. treated group
Ontology mappings	VT:0001392 locomotor behavior trait VT:0010487 response to xenobiotic stimulus trait VT:0010716 anxiety-related behavior trait MP:0001362 abnormal anxiety-related response MP:0001392 abnormal locomotor behavior MP:0009745 abnormal behavioral response to xenobiotic

Values Means Δ Means Z-scores

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Gershenfeld1 - distance traveled in 5 min

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	1	2368.4618	2368.4618	0.0118	0.9138
strain	11	61180064.6943	5561824.0631	27.6787	< 0.0001
group:strain	11	2295453.1495	208677.559	1.0385	0.4191
Residuals	99	19893272.296	200942.1444

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Gershenfeld1	16212	open field test	imipramine	distance traveled in 5 min [cm] baseline OFTactivity	inbred	12	m	5-10wks
Gershenfeld1	16213	open field test	imipramine	distance traveled in 5 min [cm] imipramine 30mg/kg OFTactivity_Rx	inbred	12	m	5-10wks