MPD: Project measures / variables set: Crabbe3 ARR1

Project measures / variables set: Crabbe3 ARR1_20rpm

ID, description, units	MPD:15840 ARR1_20rpm latency to-fall, accelerating rotarod, test day 1 20 rpm/min (ARR1) [s] ethanol study
Measures	• baseline • ethanol • difference
Data set, strains	Crabbe3 inbred 8 strains sex: both age: 9-17wks
Procedure	rotarod
Comparison	repeated measures, baseline then treated, same cohort
Ontology mappings	VT:0001516 motor coordination/balance trait VT:0010489 response to alcohol trait MP:0001516 abnormal motor coordination/balance MP:0020157 abnormal behavioral response to alcohol

Values Means Δ Means Z-scores

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Crabbe3 - latency to-fall, accelerating rotarod, test day 1 20 rpm/min (ARR1)

ANOVA Summary "within" = Within error "between" = Between Error (Animal ID)

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
between sex	1	438.095	438.095	1.8172	0.1819
between strain	7	13232.7917	1890.3988	7.8413	< 0.0001
between sex:strain	7	1968.8765	281.2681	1.1667	0.3328
between Residuals	71	17116.9268	241.0835
within group	1	3.4216	3.4216	0.0178	0.8943
within group:sex	1	1.0641	1.0641	0.0055	0.9409
within group:strain	7	5461.0705	780.1529	4.056	0.0009
within group:sex:strain	7	1389.7752	198.5393	1.0322	0.4166
within Residuals	71	13656.6385	192.347

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Crabbe3	15840	rotarod	ethanol	latency to-fall, accelerating rotarod, test day 1 20 rpm/min (ARR1) [s] baseline ARR1_pre_20rpm	inbred	8	both	9-17wks
Crabbe3	15841	rotarod	ethanol	latency to-fall, accelerating rotarod, test day 1 20 rpm/min (ARR1) [s] ethanol ARR1_post_20rpm	inbred	8	both	9-17wks
Crabbe3	15842	rotarod	ethanol	latency to-fall, accelerating rotarod, test day 1 20 rpm/min (ARR1) [s] difference ARR1_chg_20rpm	inbred	8	both	9-17wks	(supplemental / summary measure)