MPD: Project measures / variables set: Graubert1 carcinoma

Project measures / variables set: Graubert1 carcinoma_lung

ID, description, units	MPD:11617 carcinoma_lung lung carcinoma frequency rate [score] ENU study
Measures	• control • ENU
Data set, strains	Graubert1 inbred 20 strains sex: both age: 13-68wks
Procedure	histopathology
Comparison	control group vs. treated group
Ontology mappings	VT:0001175 lung morphology trait VT:0010487 response to xenobiotic stimulus trait MA:0000415 lung MP:0008872 abnormal physiological response to xenobiotic MP:0010639 altered tumor pathology MP:0013151 abnormal incidence of induced tumors

Values Means Δ Means Z-scores

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Graubert1 - lung carcinoma frequency rate

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	1	1.6096	1.6096	37.962	< 0.0001
sex	1	0.098	0.098	2.3107	0.1293
strain	18	4.3531	0.2418	5.7037	< 0.0001
group:sex	1	0.0811	0.0811	1.9138	0.1674
group:strain	18	3.6542	0.203	4.7879	< 0.0001
sex:strain	18	1.3548	0.0753	1.7751	0.0265
group:sex:strain	18	1.0292	0.0572	1.3485	0.1545
Residuals	373	15.8155	0.0424

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Graubert1	11617	histopathology	ENU	lung carcinoma frequency rate [score] control carcinoma_lung	inbred	20	both	13-68wks
Graubert1	11657	histopathology	ENU	lung carcinoma frequency rate [score] ENU carcinoma_lung_enu	inbred	20	both	13-68wks