MPD: Project measures / variables set: Noll1 IgG3

Project measures / variables set: Noll1 IgG3

ID, description, units	MPD:112622 IgG3 immunoglobulin G3 (serum IgG3) area under curve (AUC) post-infection [AUC] influenza A (H1N1) virus study
Measures	• post-infection: • day 7 • day 10 • day 15 • day 29 • day 45
Data set, strains	Noll1 CC RIX 46 strains sex: f age: 8-12 wks
Procedure	immunoglobulin quantification
Comparison	timecourse but different cohorts
Ontology mappings	VT:0008498 blood immunoglobulin G3 amount MA:0002502 serum MP:0020179 abnormal IgG3 level

Values Means Δ Means Z-scores

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Noll1 - immunoglobulin G3 (serum IgG3) area under curve (AUC) post-infection

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
post-infection	4	153.5911	38.3978	42.1845	< 0.0001
strain	10	218.5007	21.8501	24.0049	< 0.0001
post-infection:strain	40	175.6066	4.3902	4.8231	< 0.0001
Residuals	156	141.9965	0.9102

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Noll1	112622	immunoglobulin quantification	influenza A (H1N1) virus	immunoglobulin G3 (serum IgG3) area under curve (AUC) post-infection [AUC] day 7 IgG3_d7	CC RIX	39	f	8-12 wks
Noll1	112623	immunoglobulin quantification	influenza A (H1N1) virus	immunoglobulin G3 (serum IgG3) area under curve (AUC) post-infection [AUC] day 10 IgG3_d10	CC RIX	37	f	8-12 wks
Noll1	112624	immunoglobulin quantification	influenza A (H1N1) virus	immunoglobulin G3 (serum IgG3) area under curve (AUC) post-infection [AUC] day 15 IgG3_d15	CC RIX	35	f	8-12 wks
Noll1	112625	immunoglobulin quantification	influenza A (H1N1) virus	immunoglobulin G3 (serum IgG3) area under curve (AUC) post-infection [AUC] day 29 IgG3_d29	CC RIX	25	f	8-12 wks
Noll1	112626	immunoglobulin quantification	influenza A (H1N1) virus	immunoglobulin G3 (serum IgG3) area under curve (AUC) post-infection [AUC] day 45 IgG3_d45	CC RIX	34	f	8-12 wks