Project measure / variable:   Willott1   PPI_4

ID, description, units MPD:9108   PPI_4   mean prepulse inhibition (PPI), 70dB   [ratio]  4 kHz  
Data set, strains Willott1   inbred w/CC7   40 strains     sex: both     age: 5-6wks
Procedure acoustic startle test
Ontology mappings

  STRAIN COMPARISON PLOT
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Willott1 - mean prepulse inhibition (PPI), 70dB 4 kHz



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested40 strains40 strains
Mean of the strain means0.778   ratio 0.797   ratio
Median of the strain means0.764   ratio 0.807   ratio
SD of the strain means± 0.152 ± 0.147
Coefficient of variation (CV)0.195 0.185
Min–max range of strain means0.510   –   1.10   ratio 0.550   –   1.17   ratio
Mean sample size per strain10.1   mice 10.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.078 0.078 1.3648 0.2431
strain 39 15.4054 0.395 6.9091 < 0.0001
sex:strain 39 1.8718 0.048 0.8395 0.7462
Residuals 725 41.4502 0.0572


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.608 0.286   10 0.0905 0.47 0.299, 1.03 -1.12
129S1/SvImJ m 0.617 0.236   10 0.0748 0.383 0.306, 0.968 -1.22
A/J f 1.05 0.228   10 0.0722 0.217 0.714, 1.45 1.79
A/J m 0.937 0.182   10 0.0575 0.194 0.533, 1.18 0.95
AKR/J f 0.555 0.16   10 0.0506 0.288 0.402, 0.924 -1.47
AKR/J m 0.637 0.217   10 0.0687 0.341 0.353, 1.06 -1.09
BALB/cJ f 0.76 0.248   18 0.0584 0.326 0.493, 1.27 -0.12
BALB/cJ m 0.849 0.207   10 0.0654 0.244 0.669, 1.38 0.35
BTBR T+ Itpr3tf/J f 0.698 0.247   10 0.078 0.353 0.329, 1.03 -0.53
BTBR T+ Itpr3tf/J m 0.654 0.172   10 0.0544 0.263 0.425, 0.935 -0.97
BUB/BnJ f 0.946 0.169   10 0.0534 0.178 0.731, 1.21 1.11
BUB/BnJ m 0.921 0.183   10 0.0579 0.199 0.645, 1.17 0.84
C3H/HeJ f 0.864 0.158   10 0.0499 0.183 0.622, 1.13 0.57
C3H/HeJ m 0.786 0.22   10 0.0695 0.28 0.39, 1.14 -0.07
C57BL/10J f 0.581 0.182   10 0.0576 0.313 0.324, 1.0 -1.3
C57BL/10J m 0.588 0.13   10 0.0413 0.222 0.323, 0.747 -1.42
C57BL/6J f 0.811 0.175   11 0.0528 0.216 0.55, 1.1 0.22
C57BL/6J m 0.906 0.235   10 0.0744 0.26 0.543, 1.27 0.74
C57BLKS/J f 0.698 0.221   10 0.0697 0.316 0.43, 1.08 -0.53
C57BLKS/J m 0.735 0.19   10 0.0601 0.258 0.509, 1.04 -0.42
C57BR/cdJ f 0.725 0.186   10 0.0587 0.256 0.466, 0.992 -0.35
C57BR/cdJ m 0.984 0.177   10 0.0559 0.18 0.622, 1.21 1.27
C57L/J f 1.1 0.35   10 0.111 0.319 0.52, 1.54 2.12
C57L/J m 1.17 0.433   10 0.137 0.371 0.7, 1.92 2.53
C58/J f 0.523 0.2   10 0.0632 0.382 0.2, 0.854 -1.68
C58/J m 0.569 0.267   10 0.0844 0.469 0.203, 1.17 -1.55
CAST/EiJ f 0.841 0.218   10 0.0689 0.259 0.544, 1.23 0.42
CAST/EiJ m 0.91 0.277   10 0.0875 0.304 0.47, 1.35 0.77
CBA/J f 0.72 0.234   9 0.078 0.325 0.508, 1.26 -0.38
CBA/J m 0.846 0.315   10 0.0997 0.373 0.524, 1.55 0.33
CE/J f 0.67 0.172   10 0.0545 0.257 0.462, 0.915 -0.71
CE/J m 0.798 0.158   10 0.05 0.198 0.545, 1.02 0.01
CZECHII/EiJ f 0.572 0.155   9 0.0517 0.271 0.413, 0.848 -1.36
CZECHII/EiJ m 0.55 0.221   11 0.0667 0.402 0.358, 1.1 -1.68
DBA/2J f 1.0 0.345   10 0.109 0.345 0.495, 1.66 1.46
DBA/2J m 0.877 0.176   10 0.0556 0.201 0.667, 1.13 0.54
FVB/NJ f 0.863 0.265   10 0.0838 0.307 0.476, 1.34 0.56
FVB/NJ m 0.746 0.249   10 0.0789 0.334 0.402, 1.27 -0.35
I/LnJ f 0.863 0.237   10 0.075 0.275 0.448, 1.16 0.56
I/LnJ m 1.02 0.407   10 0.129 0.4 0.499, 2.0 1.51
JF1/MsJ f 1.01 0.204   10 0.0645 0.202 0.655, 1.29 1.53
JF1/MsJ m 0.945 0.259   10 0.0819 0.274 0.649, 1.44 1.0
KK/HlJ f 0.96 0.3   10 0.0949 0.313 0.629, 1.51 1.2
KK/HlJ m 0.952 0.209   10 0.0661 0.219 0.731, 1.42 1.05
LP/J f 0.57 0.243   10 0.0768 0.426 0.327, 1.06 -1.37
LP/J m 0.681 0.248   10 0.0786 0.365 0.348, 1.01 -0.79
MA/MyJ f 0.776 0.212   10 0.0671 0.273 0.459, 1.09 -0.01
MA/MyJ m 0.768 0.237   10 0.0751 0.309 0.326, 1.1 -0.2
MOLF/EiJ f 0.871 0.146   10 0.046 0.167 0.668, 1.09 0.61
MOLF/EiJ m 0.888 0.154   10 0.0488 0.174 0.548, 1.07 0.62
MSM/MsJ f 0.759 0.185   10 0.0584 0.244 0.439, 0.943 -0.12
MSM/MsJ m 0.654 0.255   10 0.0806 0.39 0.324, 1.05 -0.97
NOD/ShiLtJ f 0.784 0.258   10 0.0815 0.329 0.477, 1.3 0.04
NOD/ShiLtJ m 0.89 0.499   10 0.158 0.561 0.302, 1.97 0.63
NON/ShiLtJ f 0.853 0.234   11 0.0705 0.274 0.535, 1.37 0.5
NON/ShiLtJ m 0.817 0.271   9 0.0904 0.332 0.465, 1.31 0.14
NZB/BlNJ f 0.759 0.212   10 0.0669 0.278 0.477, 1.09 -0.12
NZB/BlNJ m 0.747 0.201   10 0.0636 0.269 0.567, 1.22 -0.34
NZW/LacJ f 0.717 0.198   10 0.0626 0.276 0.437, 1.1 -0.4
NZW/LacJ m 0.696 0.187   10 0.0593 0.269 0.47, 1.05 -0.69
PERA/EiJ f 0.847 0.166   10 0.0526 0.196 0.618, 1.07 0.46
PERA/EiJ m 0.855 0.111   10 0.0352 0.13 0.71, 1.05 0.39
PL/J f 0.762 0.39   10 0.123 0.512 0.327, 1.76 -0.1
PL/J m 0.6 0.178   10 0.0561 0.296 0.374, 1.02 -1.34
PWK/PhJ f 0.872 0.259   8 0.0917 0.297 0.597, 1.27 0.62
PWK/PhJ m 0.853 0.24   10 0.0759 0.281 0.394, 1.28 0.38
RIIIS/J f 0.732 0.228   10 0.072 0.311 0.463, 1.05 -0.3
RIIIS/J m 0.635 0.163   10 0.0515 0.257 0.466, 1.03 -1.1
SEA/GnJ f 0.766 0.212   14 0.0566 0.276 0.374, 1.03 -0.08
SEA/GnJ m 0.958 0.301   10 0.0951 0.314 0.58, 1.53 1.09
SJL/J f 0.889 0.234   10 0.074 0.263 0.508, 1.3 0.73
SJL/J m 0.97 0.406   10 0.128 0.419 0.593, 2.01 1.17
SM/J f 0.624 0.136   10 0.0431 0.218 0.49, 0.839 -1.01
SM/J m 0.671 0.198   10 0.0626 0.295 0.36, 1.1 -0.86
SPRET/EiJ f 0.594 0.187   10 0.0593 0.315 0.337, 1.01 -1.21
SPRET/EiJ m 0.767 0.171   10 0.054 0.222 0.56, 1.07 -0.2
SWR/J f 0.51 0.17   10 0.0537 0.333 0.3, 0.914 -1.76
SWR/J m 0.571 0.234   10 0.0741 0.411 0.207, 1.03 -1.53
WSB/EiJ f 1.01 0.276   7 0.104 0.273 0.639, 1.4 1.53
WSB/EiJ m 0.864 0.262   8 0.0927 0.304 0.587, 1.33 0.45


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.6084 0.0756 0.7568 0.46
129S1/SvImJ m 0.6169 0.0756 0.7653 0.4685
A/J f 1.0528 0.0756 1.2013 0.9044
A/J m 0.9367 0.0756 1.0852 0.7883
AKR/J f 0.5552 0.0756 0.7036 0.4068
AKR/J m 0.6367 0.0756 0.7851 0.4883
BALB/cJ f 0.7599 0.0564 0.8706 0.6493
BALB/cJ m 0.8492 0.0756 0.9976 0.7008
BTBR T+ Itpr3tf/J f 0.6979 0.0756 0.8464 0.5495
BTBR T+ Itpr3tf/J m 0.6536 0.0756 0.802 0.5052
BUB/BnJ f 0.9458 0.0756 1.0942 0.7973
BUB/BnJ m 0.9207 0.0756 1.0691 0.7722
C3H/HeJ f 0.8641 0.0756 1.0125 0.7157
C3H/HeJ m 0.7857 0.0756 0.9342 0.6373
C57BL/10J f 0.5809 0.0756 0.7293 0.4324
C57BL/10J m 0.588 0.0756 0.7364 0.4396
C57BL/6J f 0.8112 0.0721 0.9528 0.6697
C57BL/6J m 0.9059 0.0756 1.0543 0.7575
C57BLKS/J f 0.6975 0.0756 0.8459 0.5491
C57BLKS/J m 0.7349 0.0756 0.8833 0.5865
C57BR/cdJ f 0.7253 0.0756 0.8737 0.5768
C57BR/cdJ m 0.9843 0.0756 1.1328 0.8359
C57L/J f 1.098 0.0756 1.2464 0.9496
C57L/J m 1.1673 0.0756 1.3157 1.0189
C58/J f 0.5229 0.0756 0.6713 0.3744
C58/J m 0.5687 0.0756 0.7171 0.4203
CAST/EiJ f 0.8406 0.0756 0.989 0.6922
CAST/EiJ m 0.91 0.0756 1.0584 0.7615
CBA/J f 0.7199 0.0797 0.8764 0.5635
CBA/J m 0.8458 0.0756 0.9942 0.6974
CE/J f 0.6703 0.0756 0.8187 0.5219
CE/J m 0.7983 0.0756 0.9467 0.6499
CZECHII/EiJ f 0.5724 0.0797 0.7289 0.4159
CZECHII/EiJ m 0.5505 0.0721 0.692 0.409
DBA/2J f 1.0016 0.0756 1.15 0.8531
DBA/2J m 0.8769 0.0756 1.0253 0.7285
FVB/NJ f 0.8627 0.0756 1.0111 0.7142
FVB/NJ m 0.7465 0.0756 0.8949 0.5981
I/LnJ f 0.863 0.0756 1.0114 0.7145
I/LnJ m 1.0173 0.0756 1.1658 0.8689
JF1/MsJ f 1.0102 0.0756 1.1586 0.8618
JF1/MsJ m 0.9452 0.0756 1.0936 0.7967
KK/HlJ f 0.9601 0.0756 1.1085 0.8117
KK/HlJ m 0.9518 0.0756 1.1002 0.8034
LP/J f 0.5702 0.0756 0.7186 0.4218
LP/J m 0.6807 0.0756 0.8292 0.5323
MA/MyJ f 0.7763 0.0756 0.9247 0.6279
MA/MyJ m 0.7683 0.0756 0.9167 0.6199
MOLF/EiJ f 0.8712 0.0756 1.0196 0.7227
MOLF/EiJ m 0.8877 0.0756 1.0361 0.7393
MSM/MsJ f 0.7588 0.0756 0.9072 0.6103
MSM/MsJ m 0.6543 0.0756 0.8027 0.5059
NOD/ShiLtJ f 0.7836 0.0756 0.932 0.6351
NOD/ShiLtJ m 0.8898 0.0756 1.0383 0.7414
NON/ShiLtJ f 0.853 0.0721 0.9945 0.7114
NON/ShiLtJ m 0.8172 0.0797 0.9736 0.6607
NZB/BlNJ f 0.7595 0.0756 0.9079 0.611
NZB/BlNJ m 0.7471 0.0756 0.8956 0.5987
NZW/LacJ f 0.7166 0.0756 0.865 0.5681
NZW/LacJ m 0.6957 0.0756 0.8441 0.5473
PERA/EiJ f 0.8472 0.0756 0.9956 0.6988
PERA/EiJ m 0.8555 0.0756 1.0039 0.7071
PL/J f 0.762 0.0756 0.9104 0.6135
PL/J m 0.5999 0.0756 0.7483 0.4515
PWK/PhJ f 0.872 0.0845 1.038 0.706
PWK/PhJ m 0.8528 0.0756 1.0012 0.7043
RIIIS/J f 0.7319 0.0756 0.8803 0.5835
RIIIS/J m 0.6347 0.0756 0.7832 0.4863
SEA/GnJ f 0.766 0.0639 0.8915 0.6406
SEA/GnJ m 0.9581 0.0756 1.1065 0.8096
SJL/J f 0.8895 0.0756 1.0379 0.7411
SJL/J m 0.9701 0.0756 1.1186 0.8217
SM/J f 0.6236 0.0756 0.772 0.4752
SM/J m 0.6712 0.0756 0.8197 0.5228
SPRET/EiJ f 0.5942 0.0756 0.7426 0.4458
SPRET/EiJ m 0.7672 0.0756 0.9157 0.6188
SWR/J f 0.5101 0.0756 0.6585 0.3617
SWR/J m 0.571 0.0756 0.7195 0.4226
WSB/EiJ f 1.0127 0.0904 1.1901 0.8353
WSB/EiJ m 0.8641 0.0845 1.0301 0.6982


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.6126 0.0535 0.7176 0.5077
A/J both 0.9948 0.0535 1.0998 0.8898
AKR/J both 0.5959 0.0535 0.7009 0.491
BALB/cJ both 0.8046 0.0472 0.8971 0.712
BTBR T+ Itpr3tf/J both 0.6758 0.0535 0.7807 0.5708
BUB/BnJ both 0.9332 0.0535 1.0382 0.8282
C3H/HeJ both 0.8249 0.0535 0.9299 0.72
C57BL/10J both 0.5844 0.0535 0.6894 0.4795
C57BL/6J both 0.8586 0.0522 0.9611 0.756
C57BLKS/J both 0.7162 0.0535 0.8212 0.6112
C57BR/cdJ both 0.8548 0.0535 0.9598 0.7498
C57L/J both 1.1326 0.0535 1.2376 1.0277
C58/J both 0.5458 0.0535 0.6507 0.4408
CAST/EiJ both 0.8753 0.0535 0.9802 0.7703
CBA/J both 0.7829 0.0549 0.8907 0.675
CE/J both 0.7343 0.0535 0.8393 0.6293
CZECHII/EiJ both 0.5614 0.0537 0.6669 0.4559
DBA/2J both 0.9392 0.0535 1.0442 0.8343
FVB/NJ both 0.8046 0.0535 0.9095 0.6996
I/LnJ both 0.9401 0.0535 1.0451 0.8352
JF1/MsJ both 0.9777 0.0535 1.0826 0.8727
KK/HlJ both 0.956 0.0535 1.0609 0.851
LP/J both 0.6255 0.0535 0.7304 0.5205
MA/MyJ both 0.7723 0.0535 0.8773 0.6673
MOLF/EiJ both 0.8794 0.0535 0.9844 0.7745
MSM/MsJ both 0.7065 0.0535 0.8115 0.6016
NOD/ShiLtJ both 0.8367 0.0535 0.9417 0.7317
NON/ShiLtJ both 0.8351 0.0537 0.9406 0.7296
NZB/BlNJ both 0.7533 0.0535 0.8583 0.6483
NZW/LacJ both 0.7061 0.0535 0.8111 0.6012
PERA/EiJ both 0.8513 0.0535 0.9563 0.7464
PL/J both 0.6809 0.0535 0.7859 0.576
PWK/PhJ both 0.8624 0.0567 0.9737 0.751
RIIIS/J both 0.6833 0.0535 0.7883 0.5784
SEA/GnJ both 0.862 0.0495 0.9592 0.7649
SJL/J both 0.9298 0.0535 1.0348 0.8249
SM/J both 0.6474 0.0535 0.7524 0.5425
SPRET/EiJ both 0.6807 0.0535 0.7857 0.5758
SWR/J both 0.5406 0.0535 0.6455 0.4356
WSB/EiJ both 0.9384 0.0619 1.0599 0.8169




  GWAS USING LINEAR MIXED MODELS