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Project measure / variable:   Willott1   ASR_80

ID, description, units MPD:9103   ASR_80   acoustic startle response (ASR)   [amplitude]  evoked by 80 dB sound pressure level  
Data set, strains Willott1   inbred w/CC7   40 strains     sex: both     age: 5-6wks
Procedure acoustic startle test
Ontology mappings

  STRAIN COMPARISON PLOT
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Willott1 - acoustic startle response (ASR) evoked by 80 dB sound pressure level



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested40 strains40 strains
Mean of the strain means195   amplitude 182   amplitude
Median of the strain means172   amplitude 150   amplitude
SD of the strain means± 115 ± 103
Coefficient of variation (CV)0.590 0.567
Min–max range of strain means56.0   –   516   amplitude 51.5   –   457   amplitude
Mean sample size per strain10.1   mice 10.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 58923.0881 58923.0881 3.3396 0.068
strain 39 8555002.5125 219359.0388 12.4325 < 0.0001
sex:strain 39 852641.7857 21862.6099 1.2391 0.1538
Residuals 725 12791895.0096 17643.9931


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 167.0 57.8   10 18.3 0.347 91.2, 254.0 -0.24
129S1/SvImJ m 179.0 62.3   10 19.7 0.348 106.0, 292.0 -0.03
A/J f 227.0 121.0   10 38.4 0.535 91.5, 463.0 0.28
A/J m 296.0 217.0   10 68.7 0.733 86.0, 820.0 1.1
AKR/J f 206.0 62.0   10 19.6 0.301 77.5, 280.0 0.1
AKR/J m 182.0 135.0   10 42.5 0.739 75.3, 520.0 0.0
BALB/cJ f 325.0 151.0   18 35.6 0.466 98.3, 721.0 1.13
BALB/cJ m 386.0 95.7   10 30.3 0.248 256.0, 544.0 1.97
BTBR T+ Itpr3tf/J f 103.0 43.0   10 13.6 0.418 58.9, 192.0 -0.8
BTBR T+ Itpr3tf/J m 134.0 66.2   10 20.9 0.493 68.7, 295.0 -0.47
BUB/BnJ f 401.0 259.0   10 82.0 0.647 167.0, 979.0 1.79
BUB/BnJ m 457.0 294.0   10 93.0 0.644 91.2, 922.0 2.66
C3H/HeJ f 87.7 39.5   10 12.5 0.45 47.9, 185.0 -0.93
C3H/HeJ m 135.0 37.8   10 11.9 0.28 64.3, 185.0 -0.46
C57BL/10J f 330.0 191.0   10 60.5 0.58 93.2, 581.0 1.18
C57BL/10J m 205.0 73.2   10 23.1 0.356 99.8, 363.0 0.22
C57BL/6J f 221.0 110.0   11 33.2 0.497 47.0, 362.0 0.23
C57BL/6J m 188.0 113.0   10 35.9 0.604 51.5, 350.0 0.06
C57BLKS/J f 244.0 113.0   10 35.8 0.464 122.0, 496.0 0.43
C57BLKS/J m 227.0 178.0   10 56.3 0.784 69.3, 644.0 0.43
C57BR/cdJ f 105.0 60.3   10 19.1 0.574 50.8, 246.0 -0.78
C57BR/cdJ m 79.5 25.8   10 8.15 0.324 45.0, 118.0 -0.99
C57L/J f 80.4 17.4   10 5.5 0.216 60.1, 108.0 -1.0
C57L/J m 80.3 16.7   10 5.29 0.208 58.1, 118.0 -0.99
C58/J f 240.0 177.0   10 55.9 0.737 97.7, 514.0 0.39
C58/J m 141.0 74.7   10 23.6 0.529 71.3, 294.0 -0.4
CAST/EiJ f 71.1 25.1   10 7.95 0.353 41.6, 115.0 -1.08
CAST/EiJ m 87.7 74.1   10 23.4 0.845 47.6, 296.0 -0.92
CBA/J f 146.0 38.0   9 12.7 0.261 92.3, 202.0 -0.43
CBA/J m 297.0 362.0   10 114.0 1.22 79.2, 1268.0 1.11
CE/J f 268.0 111.0   10 35.1 0.414 151.0, 444.0 0.64
CE/J m 274.0 105.0   10 33.3 0.384 87.5, 435.0 0.89
CZECHII/EiJ f 185.0 130.0   9 43.3 0.704 63.6, 475.0 -0.09
CZECHII/EiJ m 187.0 86.1   11 26.0 0.46 51.9, 396.0 0.05
DBA/2J f 103.0 59.7   10 18.9 0.581 37.6, 220.0 -0.8
DBA/2J m 117.0 54.6   10 17.3 0.467 58.2, 219.0 -0.63
FVB/NJ f 178.0 52.6   10 16.6 0.295 86.2, 244.0 -0.15
FVB/NJ m 198.0 67.5   10 21.4 0.342 80.8, 266.0 0.15
I/LnJ f 143.0 50.5   10 16.0 0.352 59.1, 244.0 -0.45
I/LnJ m 134.0 62.0   10 19.6 0.461 55.9, 246.0 -0.47
JF1/MsJ f 98.8 77.5   10 24.5 0.784 41.5, 268.0 -0.84
JF1/MsJ m 143.0 140.0   10 44.2 0.975 39.6, 441.0 -0.38
KK/HlJ f 378.0 116.0   10 36.6 0.306 174.0, 550.0 1.59
KK/HlJ m 307.0 318.0   10 101.0 1.04 81.2, 1168.0 1.21
LP/J f 68.5 15.0   10 4.75 0.219 37.7, 86.3 -1.1
LP/J m 75.7 13.5   10 4.26 0.178 56.6, 101.0 -1.03
MA/MyJ f 469.0 288.0   10 91.2 0.615 110.0, 1048.0 2.39
MA/MyJ m 439.0 185.0   10 58.5 0.421 160.0, 686.0 2.48
MOLF/EiJ f 56.0 9.18   10 2.9 0.164 45.1, 73.8 -1.21
MOLF/EiJ m 52.9 6.72   10 2.12 0.127 46.0, 67.5 -1.25
MSM/MsJ f 80.1 33.8   10 10.7 0.422 40.5, 149.0 -1.0
MSM/MsJ m 80.9 33.3   10 10.5 0.412 50.7, 167.0 -0.98
NOD/ShiLtJ f 155.0 119.0   10 37.5 0.764 59.4, 418.0 -0.35
NOD/ShiLtJ m 158.0 109.0   10 34.6 0.692 52.4, 384.0 -0.24
NON/ShiLtJ f 149.0 104.0   11 31.3 0.698 62.9, 408.0 -0.4
NON/ShiLtJ m 114.0 87.7   9 29.2 0.767 46.4, 324.0 -0.66
NZB/BlNJ f 177.0 42.4   10 13.4 0.24 117.0, 256.0 -0.16
NZB/BlNJ m 121.0 51.0   10 16.1 0.423 67.2, 232.0 -0.59
NZW/LacJ f 516.0 329.0   10 104.0 0.638 105.0, 1329.0 2.79
NZW/LacJ m 269.0 224.0   10 70.9 0.832 130.0, 859.0 0.84
PERA/EiJ f 96.1 30.5   10 9.64 0.317 61.2, 162.0 -0.86
PERA/EiJ m 77.9 24.0   10 7.58 0.308 49.9, 119.0 -1.01
PL/J f 196.0 125.0   10 39.7 0.64 78.3, 501.0 0.01
PL/J m 185.0 62.5   10 19.8 0.338 126.0, 320.0 0.03
PWK/PhJ f 62.0 21.0   8 7.44 0.339 42.0, 106.0 -1.16
PWK/PhJ m 51.5 8.59   10 2.72 0.167 41.6, 71.8 -1.27
RIIIS/J f 140.0 108.0   10 34.2 0.769 64.5, 434.0 -0.48
RIIIS/J m 103.0 45.1   10 14.2 0.438 46.0, 184.0 -0.77
SEA/GnJ f 299.0 218.0   14 58.2 0.728 94.5, 726.0 0.91
SEA/GnJ m 366.0 201.0   10 63.6 0.55 212.0, 872.0 1.78
SJL/J f 99.0 27.4   10 8.66 0.277 52.1, 138.0 -0.83
SJL/J m 103.0 24.2   10 7.65 0.235 69.2, 138.0 -0.77
SM/J f 262.0 199.0   10 63.0 0.76 72.3, 725.0 0.58
SM/J m 173.0 192.0   10 60.6 1.11 59.5, 698.0 -0.09
SPRET/EiJ f 245.0 121.0   10 38.3 0.494 102.0, 485.0 0.44
SPRET/EiJ m 131.0 61.5   10 19.5 0.469 56.1, 254.0 -0.5
SWR/J f 317.0 145.0   10 46.0 0.459 84.7, 597.0 1.06
SWR/J m 227.0 154.0   10 48.6 0.677 91.3, 533.0 0.43
WSB/EiJ f 102.0 31.5   7 11.9 0.308 64.5, 162.0 -0.81
WSB/EiJ m 130.0 47.2   8 16.7 0.364 54.6, 199.0 -0.51


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 166.585 42.0048 249.0505 84.1195
129S1/SvImJ m 179.12 42.0048 261.5855 96.6545
A/J f 226.97 42.0048 309.4355 144.5045
A/J m 296.035 42.0048 378.5005 213.5695
AKR/J f 206.2 42.0048 288.6655 123.7345
AKR/J m 182.12 42.0048 264.5855 99.6545
BALB/cJ f 324.5194 31.3085 385.9856 263.0533
BALB/cJ m 385.95 42.0048 468.4155 303.4845
BTBR T+ Itpr3tf/J f 102.945 42.0048 185.4105 20.4795
BTBR T+ Itpr3tf/J m 134.48 42.0048 216.9455 52.0145
BUB/BnJ f 400.735 42.0048 483.2005 318.2695
BUB/BnJ m 456.815 42.0048 539.2805 374.3495
C3H/HeJ f 87.685 42.0048 170.1505 5.2195
C3H/HeJ m 134.785 42.0048 217.2505 52.3195
C57BL/10J f 329.85 42.0048 412.3155 247.3845
C57BL/10J m 205.435 42.0048 287.9005 122.9695
C57BL/6J f 221.3182 40.05 299.9459 142.6904
C57BL/6J m 187.835 42.0048 270.3005 105.3695
C57BLKS/J f 244.185 42.0048 326.6505 161.7195
C57BLKS/J m 227.055 42.0048 309.5205 144.5895
C57BR/cdJ f 104.985 42.0048 187.4505 22.5195
C57BR/cdJ m 79.485 42.0048 161.9505 0.0
C57L/J f 80.415 42.0048 162.8805 0.0
C57L/J m 80.34 42.0048 162.8055 0.0
C58/J f 239.735 42.0048 322.2005 157.2695
C58/J m 141.155 42.0048 223.6205 58.6895
CAST/EiJ f 71.145 42.0048 153.6105 0.0
CAST/EiJ m 87.68 42.0048 170.1455 5.2145
CBA/J f 145.65 44.2769 232.5762 58.7238
CBA/J m 296.665 42.0048 379.1305 214.1995
CE/J f 268.385 42.0048 350.8505 185.9195
CE/J m 274.15 42.0048 356.6155 191.6845
CZECHII/EiJ f 184.7 44.2769 271.6262 97.7738
CZECHII/EiJ m 187.3773 40.05 266.005 108.7495
DBA/2J f 102.72 42.0048 185.1855 20.2545
DBA/2J m 116.85 42.0048 199.3155 34.3845
FVB/NJ f 178.33 42.0048 260.7955 95.8645
FVB/NJ m 197.585 42.0048 280.0505 115.1195
I/LnJ f 143.4 42.0048 225.8655 60.9345
I/LnJ m 134.315 42.0048 216.7805 51.8495
JF1/MsJ f 98.845 42.0048 181.3105 16.3795
JF1/MsJ m 143.415 42.0048 225.8805 60.9495
KK/HlJ f 378.05 42.0048 460.5155 295.5845
KK/HlJ m 306.75 42.0048 389.2155 224.2845
LP/J f 68.525 42.0048 150.9905 0.0
LP/J m 75.65 42.0048 158.1155 0.0
MA/MyJ f 468.65 42.0048 551.1155 386.1845
MA/MyJ m 439.4 42.0048 521.8655 356.9345
MOLF/EiJ f 56.045 42.0048 138.5105 0.0
MOLF/EiJ m 52.895 42.0048 135.3605 0.0
MSM/MsJ f 80.09 42.0048 162.5555 0.0
MSM/MsJ m 80.875 42.0048 163.3405 0.0
NOD/ShiLtJ f 155.22 42.0048 237.6855 72.7545
NOD/ShiLtJ m 158.305 42.0048 240.7705 75.8395
NON/ShiLtJ f 148.7818 40.05 227.4096 70.1541
NON/ShiLtJ m 114.3444 44.2769 201.2707 27.4182
NZB/BlNJ f 176.635 42.0048 259.1005 94.1695
NZB/BlNJ m 120.63 42.0048 203.0955 38.1645
NZW/LacJ f 516.035 42.0048 598.5005 433.5695
NZW/LacJ m 269.335 42.0048 351.8005 186.8695
PERA/EiJ f 96.12 42.0048 178.5855 13.6545
PERA/EiJ m 77.895 42.0048 160.3605 0.0
PL/J f 195.935 42.0048 278.4005 113.4695
PL/J m 185.215 42.0048 267.6805 102.7495
PWK/PhJ f 62.0 46.9627 154.1992 0.0
PWK/PhJ m 51.455 42.0048 133.9205 0.0
RIIIS/J f 140.48 42.0048 222.9455 58.0145
RIIIS/J m 102.82 42.0048 185.2855 20.3545
SEA/GnJ f 298.8214 35.5005 368.5175 229.1254
SEA/GnJ m 365.75 42.0048 448.2155 283.2845
SJL/J f 99.045 42.0048 181.5105 16.5795
SJL/J m 102.875 42.0048 185.3405 20.4095
SM/J f 262.095 42.0048 344.5605 179.6295
SM/J m 172.905 42.0048 255.3705 90.4395
SPRET/EiJ f 244.705 42.0048 327.1705 162.2395
SPRET/EiJ m 131.285 42.0048 213.7505 48.8195
SWR/J f 317.015 42.0048 399.4805 234.5495
SWR/J m 226.835 42.0048 309.3005 144.3695
WSB/EiJ f 102.4071 50.2053 200.9722 3.842
WSB/EiJ m 129.7687 46.9627 221.968 37.5695


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 172.8525 29.7018 231.1644 114.5406
A/J both 261.5025 29.7018 319.8144 203.1906
AKR/J both 194.16 29.7018 252.4719 135.8481
BALB/cJ both 355.2347 26.1946 406.661 303.8085
BTBR T+ Itpr3tf/J both 118.7125 29.7018 177.0244 60.4006
BUB/BnJ both 428.775 29.7018 487.0869 370.4631
C3H/HeJ both 111.235 29.7018 169.5469 52.9231
C57BL/10J both 267.6425 29.7018 325.9544 209.3306
C57BL/6J both 204.5766 29.019 261.5478 147.6054
C57BLKS/J both 235.62 29.7018 293.9319 177.3081
C57BR/cdJ both 92.235 29.7018 150.5469 33.9231
C57L/J both 80.3775 29.7018 138.6894 22.0656
C58/J both 190.445 29.7018 248.7569 132.1331
CAST/EiJ both 79.4125 29.7018 137.7244 21.1006
CBA/J both 221.1575 30.5157 281.0673 161.2477
CE/J both 271.2675 29.7018 329.5794 212.9556
CZECHII/EiJ both 186.0386 29.8515 244.6443 127.433
DBA/2J both 109.785 29.7018 168.0969 51.4731
FVB/NJ both 187.9575 29.7018 246.2694 129.6456
I/LnJ both 138.8575 29.7018 197.1694 80.5456
JF1/MsJ both 121.13 29.7018 179.4419 62.8181
KK/HlJ both 342.4 29.7018 400.7119 284.0881
LP/J both 72.0875 29.7018 130.3994 13.7756
MA/MyJ both 454.025 29.7018 512.3369 395.7131
MOLF/EiJ both 54.47 29.7018 112.7819 0.0
MSM/MsJ both 80.4825 29.7018 138.7944 22.1706
NOD/ShiLtJ both 156.7625 29.7018 215.0744 98.4506
NON/ShiLtJ both 131.5631 29.8515 190.1688 72.9575
NZB/BlNJ both 148.6325 29.7018 206.9444 90.3206
NZW/LacJ both 392.685 29.7018 450.9969 334.3731
PERA/EiJ both 87.0075 29.7018 145.3194 28.6956
PL/J both 190.575 29.7018 248.8869 132.2631
PWK/PhJ both 56.7275 31.5036 118.5766 0.0
RIIIS/J both 121.65 29.7018 179.9619 63.3381
SEA/GnJ both 332.2857 27.4986 386.272 278.2994
SJL/J both 100.96 29.7018 159.2719 42.6481
SM/J both 217.5 29.7018 275.8119 159.1881
SPRET/EiJ both 187.995 29.7018 246.3069 129.6831
SWR/J both 271.925 29.7018 330.2369 213.6131
WSB/EiJ both 116.0879 34.3732 183.5709 48.605




  GWAS USING LINEAR MIXED MODELS