Project measure / variable:   CSNA03   dist_f30_cocaine_in_d7

ID, description, units MPD:90355   dist_f30_cocaine_in_d7   distance traveled, first 30 min (pre-injection), on successive days, cocaine group, founders   [cm]  day 7  
cocaine study
Data set, strains CSNA03   inbred w/CC8   10 strains     sex: both     age: 8-14wks
Procedure open field test
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  STRAIN COMPARISON PLOT
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CSNA03 - distance traveled, first 30 min (pre-injection), on successive days, cocaine group, founders day 7



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means7462.0   cm 6046.0   cm
Median of the strain means6456.0   cm 6690.0   cm
SD of the strain means± 5911.0 ± 3413.0
Coefficient of variation (CV)0.7921 0.5645
Min–max range of strain means579.6   –   20554.0   cm 1155.0   –   10604.0   cm
Mean sample size per strain6.1   mice 6.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 76816091.7311 76816091.7311 4.6822 0.0327
strain 8 2335463722.0574 291932965.2572 17.7944 < 0.0001
sex:strain 8 390365306.9369 48795663.3671 2.9743 0.0048
Residuals 105 1722620989.3974 16405914.1847


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 579.6 1095.0   6 447.0 1.8893 -1.16
129S1/SvImJ m 1155.0 1052.0   6 429.7 0.9108 64.6, 2791.0 -1.43
A/J f 2345.0 1425.0   12 411.3 0.6077 273.7, 4641.0 -0.87
A/J m 2534.0 1274.0   12 367.9 0.5029 710.6, 5535.0 -1.03
C57BL/6J f 6625.0 1285.0   5 574.7 0.194 4522.0, 7990.0 -0.14
C57BL/6J m 6621.0 1302.0   7 492.2 0.1967 4409.0, 8839.0 0.17
C57BL/6NJ f 4849.0 0.0   1   0.0 0.0 4849.0, 4849.0 -0.44
C57BL/6NJ m 4324.0 0.0   1   0.0 0.0 4324.0, 4324.0 -0.5
CAST/EiJ f 20554.0 15770.0   6 6438.0 0.7672 8587.0, 50704.0 2.22
CAST/EiJ m 8487.0 2233.0   5 998.8 0.2632 6935.0, 12362.0 0.72
DBA/2J f 6287.0 1388.0   3 801.6 0.2208 4691.0, 7216.0 -0.2
DBA/2J m 9025.0 2068.0   4 1034.0 0.2291 6763.0, 11779.0 0.87
NOD/ShiLtJ f 12062.0 3339.0   6 1363.0 0.2768 6994.0, 15725.0 0.78
NOD/ShiLtJ m 10604.0 2919.0   6 1192.0 0.2753 7599.0, 15541.0 1.34
NZO/HlLtJ f 2007.0 599.8   6 244.9 0.2988 1160.0, 2530.0 -0.92
NZO/HlLtJ m 1699.0 694.7   7 262.6 0.4089 847.5, 2646.0 -1.27
PWK/PhJ f 9559.0 2011.0   9 670.5 0.2104 6095.0, 12414.0 0.35
PWK/PhJ m 9252.0 3088.0   9 1029.0 0.3338 5547.0, 14447.0 0.94
WSB/EiJ f 9751.0 4889.0   7 1848.0 0.5014 3186.0, 16783.0 0.39
WSB/EiJ m 6758.0 1777.0   7 671.5 0.2629 4262.0, 8829.0 0.21


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 579.5633333333 1653.5776458303 3858.3023458916 -2699.175679225
129S1/SvImJ m 1155.4983333333 1653.5776458303 4434.2373458916 -2123.240679225
A/J f 2344.7416666667 1169.2559665851 4663.1602561875 26.3230771458
A/J m 2533.8 1169.2559665851 4852.2185895209 215.3814104791
C57BL/6J f 6624.8 1811.4035544151 10216.4786347008 3033.1213652992
C57BL/6J m 6621.2857142857 1530.9154210442 9656.8081940206 3585.7632345508
CAST/EiJ f 20554.1666666666 1653.5776458303 23832.905679225 17275.4276541083
CAST/EiJ m 8486.8 1811.403554415 12078.4786347008 4895.1213652992
DBA/2J f 6287.0 2338.5119331701 10923.8371790417 1650.1628209583
DBA/2J m 9025.0 2025.2107411784 13040.6187902623 5009.3812097377
NOD/ShiLtJ f 12062.3333333334 1653.5776458303 15341.0723458917 8783.594320775
NOD/ShiLtJ m 10603.8333333334 1653.5776458303 13882.5723458917 7325.0943207751
NZO/HlLtJ f 2007.3333333333 1653.5776458303 5286.0723458916 -1271.405679225
NZO/HlLtJ m 1698.8857142857 1530.9154210442 4734.4081940206 -1336.6367654492
PWK/PhJ f 9559.4444444444 1350.1404941189 12236.5236379526 6882.3652509362
PWK/PhJ m 9252.3333333333 1350.1404941189 11929.4125268415 6575.2541398251
WSB/EiJ f 9751.0 1530.9154210442 12786.5224797349 6715.4775202651
WSB/EiJ m 6757.8571428571 1530.9154210442 9793.379622592 3722.3346631223


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 867.5308333333 1169.2559665851 3185.9494228542 -1450.8877561875
A/J both 2439.2708333333 826.7888229151 4078.6403396125 799.9013270542
C57BL/6J both 6623.0428571429 1185.8419860313 8974.3484593532 4271.7372549326
CAST/EiJ both 14520.4833333333 1226.3260035302 16952.061263785 12088.9054028817
DBA/2J both 7656.0 1546.7802532813 10722.9795114107 4589.0204885893
NOD/ShiLtJ both 11333.0833333334 1169.2559665851 13651.5019228542 9014.6647438125
NZO/HlLtJ both 1853.1095238095 1126.723242103 4087.1935775913 -380.9745299722
PWK/PhJ both 9405.8888888889 954.6934989461 11298.869740392 7512.9080373858
WSB/EiJ both 8254.4285714286 1082.5206756434 10400.8671012933 6107.9900415638




  GWAS USING LINEAR MIXED MODELS