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Project measure / variable:   Neuner1   cfc_14mo_baseline

ID, description, units MPD:65967   cfc_14mo_baseline   percentage of time spent freezing during 40 s interval post shock at 14 mo of age, day 1 contextual fear conditioning   [%]  baseline  
Data set, strains Neuner1   F1 AD-BXD   51 strains     sex: both     age: 55-57wks
Procedure fear conditioning test
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  STRAIN COMPARISON PLOT
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Neuner1 - percentage of time spent freezing during 40 s interval post shock at 14 mo of age, day 1 contextual fear conditioning baseline



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested48 strains35 strains
Mean of the strain means3.15   % 2.9631   %
Median of the strain means1.6547   % 2.534   %
SD of the strain means± 4.4753 ± 2.5868
Coefficient of variation (CV)1.4207 0.873
Min–max range of strain means0.0   –   20.27   % 0.0   –   10.15   %
Mean sample size per strain4.5   mice 4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.3449 0.3449 0.0206 0.886
strain 25 1420.0965 56.8039 3.3954 < 0.0001
sex:strain 25 623.6458 24.9458 1.4911 0.0686
Residuals 222 3713.9558 16.7295


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
(B6.5XFAD x B6)F1-ADtg m 3.3067 8.411   27 1.6187 2.5437 0.13
(B6.5XFAD x B6)F1-Ntg f 2.3067 4.7136   9 1.5712 2.0435 -0.19
(B6.5XFAD x B6)F1-Ntg m 5.1264 4.8805   11 1.4715 0.952 0.84
(B6.5XFAD x BXD100)F1-ADtg f 1.115 1.5768   2   1.115 1.4142 -0.45
(B6.5XFAD x BXD100)F1-ADtg m 1.5329 2.269   7 0.85762 1.4803 -0.55
(B6.5XFAD x BXD100)F1-Ntg f 5.0675 4.343   4 2.1715 0.857 0.59, 10.0 0.43
(B6.5XFAD x BXD100)F1-Ntg m 2.9533 4.2961   6 1.7539 1.4547 0.0
(B6.5XFAD x BXD14)F1-ADtg f 0.0 0.0   2   0.0 None -0.7
(B6.5XFAD x BXD14)F1-Ntg f 1.265 1.789   2   1.265 1.4142 -0.42
(B6.5XFAD x BXD16)F1-ADtg f 0.41 0.82   4 0.41 2.0 -0.61
(B6.5XFAD x BXD22)F1-ADtg f 5.97 8.4429   2   5.97 1.4142 0.63
(B6.5XFAD x BXD22)F1-Ntg f 1.64 2.3193   2   1.64 1.4142 -0.34
(B6.5XFAD x BXD32)F1-ADtg f 0.0 0.0   2   0.0 None -0.7
(B6.5XFAD x BXD32)F1-ADtg m 2.7833 2.6723   3 1.5428 0.9601 0.75, 5.81 -0.07
(B6.5XFAD x BXD32)F1-Ntg f 1.1433 1.9803   3 1.1433 1.7321 -0.45
(B6.5XFAD x BXD32)F1-Ntg m 4.1 4.9497   2   3.5 1.2073 0.6, 7.6 0.44
(B6.5XFAD x BXD42)F1-ADtg f 1.715 1.3647   2   0.965 0.7958 0.75, 2.68 -0.32
(B6.5XFAD x BXD42)F1-Ntg f 0.0 0.0   1   0.0 None -0.7
(B6.5XFAD x BXD44)F1-ADtg f 2.2831 1.8002   13 0.4993 0.7885 -0.19
(B6.5XFAD x BXD44)F1-ADtg m 2.3125 2.6479   8 0.93617 1.145 -0.25
(B6.5XFAD x BXD44)F1-Ntg f 1.34 0.0   1   0.0 0.0 1.34, 1.34 -0.4
(B6.5XFAD x BXD44)F1-Ntg m 2.7333 2.6216   3 1.5136 0.9591 0.6, 5.66 -0.09
(B6.5XFAD x BXD51)F1-ADtg f 0.64667 1.3122   6 0.5357 2.0292 -0.56
(B6.5XFAD x BXD51)F1-Ntg f 1.08 1.3618   4 0.68089 1.2609 -0.46
(B6.5XFAD x BXD55)F1-ADtg f 0.335 0.67   4 0.335 2.0 -0.63
(B6.5XFAD x BXD55)F1-Ntg f 0.0 0.0   2   0.0 None -0.7
(B6.5XFAD x BXD56)F1-ADtg m 5.22 0.0   1   0.0 0.0 5.22, 5.22 0.87
(B6.5XFAD x BXD56)F1-Ntg f 0.3 0.42426   2   0.3 1.4142 -0.64
(B6.5XFAD x BXD56)F1-Ntg m 0.0 0.0   1   0.0 None -1.15
(B6.5XFAD x BXD60)F1-ADtg f 1.9325 2.282   4 1.141 1.1809 -0.27
(B6.5XFAD x BXD60)F1-ADtg m 3.668 5.1156   5 2.2878 1.3946 0.27
(B6.5XFAD x BXD60)F1-Ntg f 3.2667 3.2151   3 1.8562 0.9842 1.19, 6.97 0.03
(B6.5XFAD x BXD61)F1-ADtg f 0.80571 1.8805   7 0.71076 2.3339 -0.52
(B6.5XFAD x BXD61)F1-ADtg m 3.62 3.1592   3 1.824 0.8727 0.25
(B6.5XFAD x BXD61)F1-Ntg f 3.148 3.4748   5 1.554 1.1038 0.0
(B6.5XFAD x BXD61)F1-Ntg m 3.6617 3.497   6 1.4277 0.955 0.27
(B6.5XFAD x BXD62)F1-ADtg f 0.44667 0.77365   3 0.44667 1.7321 -0.6
(B6.5XFAD x BXD62)F1-ADtg m 2.98 4.2144   2   2.98 1.4142 0.01
(B6.5XFAD x BXD62)F1-Ntg f 15.29 4.035   3 2.3296 0.2639 10.68, 18.18 2.71
(B6.5XFAD x BXD62)F1-Ntg m 10.043 6.434   3 3.7146 0.6406 5.96, 17.46 2.74
(B6.5XFAD x BXD65)F1-ADtg f 0.17333 0.42458   6 0.17333 2.4495 -0.67
(B6.5XFAD x BXD65)F1-ADtg m 3.575 5.0558   2   3.575 1.4142 0.24
(B6.5XFAD x BXD65)F1-Ntg f 3.2625 4.8282   8 1.707 1.4799 0.03
(B6.5XFAD x BXD65)F1-Ntg m 1.12 1.5839   2   1.12 1.4142 -0.71
(B6.5XFAD x BXD66)F1-ADtg f 12.733 19.871   3 11.472 1.5605 0.74, 35.67 2.14
(B6.5XFAD x BXD66)F1-ADtg m 2.534 4.1716   5 1.8656 1.6462 -0.17
(B6.5XFAD x BXD66)F1-Ntg f 0.0 0.0   1   0.0 None -0.7
(B6.5XFAD x BXD66)F1-Ntg m 0.25 0.43301   3 0.25 1.7321 -1.05
(B6.5XFAD x BXD68)F1-ADtg f 0.54667 0.94685   3 0.54667 1.7321 -0.58
(B6.5XFAD x BXD68)F1-ADtg m 4.2414 5.3147   7 2.0088 1.253 0.49
(B6.5XFAD x BXD68)F1-Ntg f 9.201 6.1226   10 1.9361 0.6654 1.35
(B6.5XFAD x BXD68)F1-Ntg m 0.3 0.42426   2   0.3 1.4142 -1.03
(B6.5XFAD x BXD69)F1-ADtg f 1.7567 3.2569   6 1.3296 1.854 -0.31
(B6.5XFAD x BXD69)F1-ADtg m 0.892 1.0472   5 0.46831 1.174 -0.8
(B6.5XFAD x BXD69)F1-Ntg f 2.2275 3.2913   4 1.6456 1.4776 -0.21
(B6.5XFAD x BXD69)F1-Ntg m 0.81667 1.3056   6 0.53303 1.5987 -0.83
(B6.5XFAD x BXD70)F1-ADtg f 4.33 0.0   1   0.0 0.0 4.33, 4.33 0.26
(B6.5XFAD x BXD70)F1-ADtg m 9.6467 4.1155   3 2.3761 0.4266 5.66, 13.88 2.58
(B6.5XFAD x BXD70)F1-Ntg f 1.3433 1.1658   3 0.67306 0.8678 -0.4
(B6.5XFAD x BXD70)F1-Ntg m 1.27 1.7961   2   1.27 1.4142 -0.65
(B6.5XFAD x BXD75)F1-ADtg f 0.0 0.0   4 0.0 None -0.7
(B6.5XFAD x BXD75)F1-ADtg m 1.305 1.6489   4 0.82446 1.2635 -0.64
(B6.5XFAD x BXD75)F1-Ntg f 1.84 2.6485   6 1.0813 1.4394 -0.29
(B6.5XFAD x BXD75)F1-Ntg m 2.09 0.0   1   0.0 0.0 2.09, 2.09 -0.34
(B6.5XFAD x BXD77)F1-ADtg f 10.273 9.4216   3 5.4395 0.9171 1.59
(B6.5XFAD x BXD77)F1-ADtg m 3.71 5.7969   3 3.3468 1.5625 0.29
(B6.5XFAD x BXD77)F1-Ntg f 3.086 3.3551   10 1.061 1.0872 -0.01
(B6.5XFAD x BXD77)F1-Ntg m 1.3117 1.4628   6 0.5972 1.1152 -0.64
(B6.5XFAD x BXD81)F1-ADtg f 0.0 0.0   6 0.0 None -0.7
(B6.5XFAD x BXD81)F1-Ntg f 13.638 23.068   5 10.316 1.6914 2.34
(B6.5XFAD x BXD87)F1-ADtg f 0.88 2.0986   10 0.66364 2.3848 -0.51
(B6.5XFAD x BXD87)F1-ADtg m 2.09 3.2632   4 1.6316 1.5613 -0.34
(B6.5XFAD x BXD87)F1-Ntg f 7.66 6.3736   3 3.6798 0.8321 0.6, 12.99 1.01
(B6.5XFAD x BXD87)F1-Ntg m 10.15 0.0   1   0.0 0.0 10.15, 10.15 2.78
(B6.5XFAD x BXD89)F1-ADtg m 0.0 0.0   1   0.0 None -1.15
(B6.5XFAD x BXD89)F1-Ntg f 2.015 1.3789   2   0.975 0.6843 1.04, 2.99 -0.25
(B6.5XFAD x BXD89)F1-Ntg m 0.3 0.42426   2   0.3 1.4142 -1.03
(B6.5XFAD x BXD99)F1-ADtg f 20.27 0.0   1   0.0 0.0 20.27, 20.27 3.83
(B6.5XFAD x BXD99)F1-Ntg f 2.24 0.0   1   0.0 0.0 2.24, 2.24 -0.2
(B6.5XFAD x D2)F1-ADtg f 1.6694 4.84   17 1.1739 2.8992 -0.33
(B6.5XFAD x D2)F1-ADtg m 1.7538 3.2824   8 1.1605 1.8716 -0.47
(B6.5XFAD x D2)F1-Ntg f 0.5475 0.60432   12 0.17445 1.1038 -0.58
(B6.5XFAD x D2)F1-Ntg m 2.3125 2.4814   4 1.2407 1.073 -0.25


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-Ntg f 2.3067 1.3634 4.9935 -0.3802
(B6.5XFAD x B6)F1-Ntg m 5.1264 1.2332 7.5567 2.696
(B6.5XFAD x BXD100)F1-ADtg f 1.115 2.8922 6.8147 -4.5847
(B6.5XFAD x BXD100)F1-ADtg m 1.5329 1.5459 4.5795 -1.5137
(B6.5XFAD x BXD100)F1-Ntg f 5.0675 2.0451 9.0978 1.0372
(B6.5XFAD x BXD100)F1-Ntg m 2.9533 1.6698 6.244 -0.3374
(B6.5XFAD x BXD32)F1-ADtg f 0.0 2.8922 5.6997 -5.6997
(B6.5XFAD x BXD32)F1-ADtg m 2.7833 2.3615 7.4371 -1.8704
(B6.5XFAD x BXD32)F1-Ntg f 1.1433 2.3615 5.7971 -3.5104
(B6.5XFAD x BXD32)F1-Ntg m 4.1 2.8922 9.7997 -1.5997
(B6.5XFAD x BXD44)F1-ADtg f 2.2831 1.1344 4.5187 0.0475
(B6.5XFAD x BXD44)F1-ADtg m 2.3125 1.4461 5.1623 -0.5373
(B6.5XFAD x BXD60)F1-ADtg f 1.9325 2.0451 5.9628 -2.0978
(B6.5XFAD x BXD60)F1-ADtg m 3.668 1.8292 7.2728 0.0632
(B6.5XFAD x BXD61)F1-ADtg f 0.8057 1.5459 3.8523 -2.2409
(B6.5XFAD x BXD61)F1-ADtg m 3.62 2.3615 8.2738 -1.0338
(B6.5XFAD x BXD61)F1-Ntg f 3.148 1.8292 6.7528 -0.4568
(B6.5XFAD x BXD61)F1-Ntg m 3.6617 1.6698 6.9524 0.371
(B6.5XFAD x BXD62)F1-ADtg f 0.4467 2.3615 5.1004 -4.2071
(B6.5XFAD x BXD62)F1-ADtg m 2.98 2.8922 8.6797 -2.7197
(B6.5XFAD x BXD62)F1-Ntg f 15.29 2.3615 19.9438 10.6362
(B6.5XFAD x BXD62)F1-Ntg m 10.0433 2.3615 14.6971 5.3896
(B6.5XFAD x BXD65)F1-ADtg f 0.1733 1.6698 3.464 -3.1174
(B6.5XFAD x BXD65)F1-ADtg m 3.575 2.8922 9.2747 -2.1247
(B6.5XFAD x BXD65)F1-Ntg f 3.2625 1.4461 6.1123 0.4127
(B6.5XFAD x BXD65)F1-Ntg m 1.12 2.8922 6.8197 -4.5797
(B6.5XFAD x BXD66)F1-ADtg f 12.7333 2.3615 17.3871 8.0796
(B6.5XFAD x BXD66)F1-ADtg m 2.534 1.8292 6.1388 -1.0708
(B6.5XFAD x BXD68)F1-ADtg f 0.5467 2.3615 5.2004 -4.1071
(B6.5XFAD x BXD68)F1-ADtg m 4.2414 1.5459 7.288 1.1948
(B6.5XFAD x BXD68)F1-Ntg f 9.201 1.2934 11.75 6.652
(B6.5XFAD x BXD68)F1-Ntg m 0.3 2.8922 5.9997 -5.3997
(B6.5XFAD x BXD69)F1-ADtg f 1.7567 1.6698 5.0474 -1.534
(B6.5XFAD x BXD69)F1-ADtg m 0.892 1.8292 4.4968 -2.7128
(B6.5XFAD x BXD69)F1-Ntg f 2.2275 2.0451 6.2578 -1.8028
(B6.5XFAD x BXD69)F1-Ntg m 0.8167 1.6698 4.1074 -2.474
(B6.5XFAD x BXD70)F1-Ntg f 1.3433 2.3615 5.9971 -3.3104
(B6.5XFAD x BXD70)F1-Ntg m 1.27 2.8922 6.9697 -4.4297
(B6.5XFAD x BXD75)F1-ADtg f 0.0 2.0451 4.0303 -4.0303
(B6.5XFAD x BXD75)F1-ADtg m 1.305 2.0451 5.3353 -2.7253
(B6.5XFAD x BXD77)F1-ADtg f 10.2733 2.3615 14.9271 5.6196
(B6.5XFAD x BXD77)F1-ADtg m 3.71 2.3615 8.3638 -0.9438
(B6.5XFAD x BXD77)F1-Ntg f 3.086 1.2934 5.635 0.537
(B6.5XFAD x BXD77)F1-Ntg m 1.3117 1.6698 4.6024 -1.979
(B6.5XFAD x BXD87)F1-ADtg f 0.88 1.2934 3.429 -1.669
(B6.5XFAD x BXD87)F1-ADtg m 2.09 2.0451 6.1203 -1.9403
(B6.5XFAD x BXD89)F1-Ntg f 2.015 2.8922 7.7147 -3.6847
(B6.5XFAD x BXD89)F1-Ntg m 0.3 2.8922 5.9997 -5.3997
(B6.5XFAD x D2)F1-ADtg f 1.6694 0.992 3.6244 -0.2856
(B6.5XFAD x D2)F1-ADtg m 1.7537 1.4461 4.6036 -1.0961
(B6.5XFAD x D2)F1-Ntg f 0.5475 1.1807 2.8744 -1.7794
(B6.5XFAD x D2)F1-Ntg m 2.3125 2.0451 6.3428 -1.7178


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-Ntg both 3.7165 0.9192 5.528 1.905
(B6.5XFAD x BXD100)F1-ADtg both 1.3239 1.6397 4.5553 -1.9075
(B6.5XFAD x BXD100)F1-Ntg both 4.0104 1.3201 6.6119 1.4089
(B6.5XFAD x BXD32)F1-ADtg both 1.3917 1.8669 5.0708 -2.2874
(B6.5XFAD x BXD32)F1-Ntg both 2.6217 1.8669 6.3008 -1.0574
(B6.5XFAD x BXD44)F1-ADtg both 2.2978 0.919 4.1088 0.4868
(B6.5XFAD x BXD60)F1-ADtg both 2.8002 1.3719 5.5038 0.0967
(B6.5XFAD x BXD61)F1-ADtg both 2.2129 1.4112 4.994 -0.5683
(B6.5XFAD x BXD61)F1-Ntg both 3.4048 1.2384 5.8453 0.9644
(B6.5XFAD x BXD62)F1-ADtg both 1.7133 1.8669 5.3924 -1.9658
(B6.5XFAD x BXD62)F1-Ntg both 12.6667 1.6698 15.9574 9.376
(B6.5XFAD x BXD65)F1-ADtg both 1.8742 1.6698 5.1649 -1.4165
(B6.5XFAD x BXD65)F1-Ntg both 2.1912 1.6168 5.3775 -0.995
(B6.5XFAD x BXD66)F1-ADtg both 7.6337 1.4935 10.577 4.6904
(B6.5XFAD x BXD68)F1-ADtg both 2.394 1.4112 5.1752 -0.3871
(B6.5XFAD x BXD68)F1-Ntg both 4.7505 1.5841 7.8723 1.6287
(B6.5XFAD x BXD69)F1-ADtg both 1.3243 1.2384 3.7648 -1.1161
(B6.5XFAD x BXD69)F1-Ntg both 1.5221 1.3201 4.1236 -1.0794
(B6.5XFAD x BXD70)F1-Ntg both 1.3067 1.8669 4.9858 -2.3724
(B6.5XFAD x BXD75)F1-ADtg both 0.6525 1.4461 3.5023 -2.1973
(B6.5XFAD x BXD77)F1-ADtg both 6.9917 1.6698 10.2824 3.701
(B6.5XFAD x BXD77)F1-Ntg both 2.1988 1.0561 4.2801 0.1176
(B6.5XFAD x BXD87)F1-ADtg both 1.485 1.2099 3.8693 -0.8993
(B6.5XFAD x BXD89)F1-Ntg both 1.1575 2.0451 5.1878 -2.8728
(B6.5XFAD x D2)F1-ADtg both 1.7116 0.8768 3.4395 -0.0164
(B6.5XFAD x D2)F1-Ntg both 1.43 1.1807 3.7569 -0.8969




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA