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Project measure / variable:   Lesage1   CD4_pos_CD8_neg_of_tot

ID, description, units MPD:63517   CD4_pos_CD8_neg_of_tot   percentage of splenic lymphocytes that are CD4+ T cells   [%]  
Data set, strains Lesage1   CC w/par   76 strains     sex: both     age: 5-8wks
Procedure immune cell quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Lesage1 - percentage of splenic lymphocytes that are CD4+ T cells



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested46 strains65 strains
Mean of the strain means10.482   % 9.5295   %
Median of the strain means8.78   % 8.5167   %
SD of the strain means± 5.422 ± 4.5366
Coefficient of variation (CV)0.5173 0.4761
Min–max range of strain means3.32   –   26.2   % 2.0967   –   25.3   %
Mean sample size per strain2.2   mice 2.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 12.8616 12.8616 5.1743 0.029
strain 12 1038.6664 86.5555 34.8222 < 0.0001
sex:strain 12 34.8175 2.9015 1.1673 0.3418
Residuals 36 89.4831 2.4856


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 7.4 0.79196   2   0.56 0.107 6.84, 7.96 -0.57
129S1/SvImJ m 10.55 0.49497   2   0.35 0.0469 10.2, 10.9 0.22
A/J f 5.775 0.00707107   2   0.005 0.0012 5.77, 5.78 -0.87
A/J m 7.125 1.1526   2   0.815 0.1618 6.31, 7.94 -0.53
C57BL/6J f 7.175 1.691   4 0.84548 0.2357 5.0, 9.13 -0.61
C57BL/6J m 15.3 0.0   1   0.0 0.0 15.3, 15.3 1.27
CAST/EiJ f 3.32 1.3294   2   0.94 0.4004 2.38, 4.26 -1.32
CAST/EiJ m 4.075 2.3122   2   1.635 0.5674 2.44, 5.71 -1.2
CC008/Geni m 11.72 5.481   3 3.1644 0.4677 7.9, 18.0 0.48
CC010/Geni f 20.45 0.91924   2   0.65 0.045 19.8, 21.1 1.84
CC010/Geni m 25.3 0.0   1   0.0 0.0 25.3, 25.3 3.48
CC012/Geni f 4.095 0.55861   2   0.395 0.1364 3.7, 4.49 -1.18
CC012/Geni m 2.3733 0.33724   3 0.19471 0.1421 2.14, 2.76 -1.58
CC013/Geni m 3.68 0.54525   3 0.3148 0.1482 3.07, 4.12 -1.29
CC016/Geni m 5.6567 0.31896   3 0.18415 0.0564 5.29, 5.87 -0.85
CC020/Geni f 14.3 0.0   1   0.0 0.0 14.3, 14.3 0.7
CC020/Geni m 10.95 0.77782   2   0.55 0.071 10.4, 11.5 0.31
CC023/Geni m 6.3867 0.92154   3 0.53205 0.1443 5.82, 7.45 -0.69
CC024/Geni f 6.595 0.84146   2   0.595 0.1276 6.0, 7.19 -0.72
CC024/Geni m 7.31 0.0   1   0.0 0.0 7.31, 7.31 -0.49
CC025/Geni f 15.2 1.3115   3 0.75719 0.0863 14.0, 16.6 0.87
CC026/Geni m 4.12 0.58026   3 0.33501 0.1408 3.69, 4.78 -1.19
CC027/Geni f 4.84 0.0   1   0.0 0.0 4.84, 4.84 -1.04
CC027/Geni m 6.0 0.35355   2   0.25 0.0589 5.75, 6.25 -0.78
CC030/Geni f 5.82 0.98995   2   0.7 0.1701 5.12, 6.52 -0.86
CC031/Geni f 6.65 0.0   1   0.0 0.0 6.65, 6.65 -0.71
CC031/Geni m 5.58 0.6364   2   0.45 0.114 5.13, 6.03 -0.87
CC032/Geni m 9.35 0.60655   3 0.35019 0.0649 8.77, 9.98 -0.04
CC033/Geni f 3.8233 0.4236   3 0.24456 0.1108 3.49, 4.3 -1.23
CC038/Geni f 4.325 0.72832   2   0.515 0.1684 3.81, 4.84 -1.14
CC038/Geni m 5.06 0.0   1   0.0 0.0 5.06, 5.06 -0.99
CC042/Geni m 9.51 1.1842   3 0.68369 0.1245 8.25, 10.6 0.0
CC043/Geni m 15.933 1.2055   3 0.69602 0.0757 14.8, 17.2 1.41
CC056/Geni f 16.1 0.0   1   0.0 0.0 16.1, 16.1 1.04
CC056/Geni m 14.05 0.21213   2   0.15 0.0151 13.9, 14.2 1.0
CC061/Geni m 7.7667 0.74232   3 0.42858 0.0956 7.27, 8.62 -0.39
CIV2_FE f 9.66 0.91198   3 0.52653 0.0944 8.69, 10.5 -0.15
DET3_GA m 14.7 1.1533   3 0.66583 0.0785 13.6, 15.9 1.14
DONNELL_HA f 16.1 0.28284   2   0.2 0.0176 15.9, 16.3 1.04
DONNELL_HA m 16.2 1.7321   3 1.0 0.1069 15.2, 18.2 1.47
FIV_AC m 13.71 4.4138   4 2.2069 0.3219 9.85, 18.2 0.92
FUF_HE f 14.633 1.0066   3 0.58119 0.0688 13.7, 15.7 0.77
GALASUPREME_CE m 5.96 0.72691   3 0.41968 0.122 5.34, 6.76 -0.79
GIT_GC f 9.99 0.0   1   0.0 0.0 9.99, 9.99 -0.09
GIT_GC m 10.435 1.3647   2   0.965 0.1308 9.47, 11.4 0.2
HAX2_EF f 5.8 0.27221   3 0.15716 0.0469 5.6, 6.11 -0.86
HAZ_FE f 12.2 0.0   1   0.0 0.0 12.2, 12.2 0.32
HAZ_FE m 13.6 0.0   2   0.0 0.0 13.6, 13.6 0.9
HIP_GA f 13.7 0.0   1   0.0 0.0 13.7, 13.7 0.59
HIP_GA m 14.65 0.77782   2   0.55 0.0531 14.1, 15.2 1.13
HOE_GC f 8.2 0.0   1   0.0 0.0 8.2, 8.2 -0.42
HOE_GC m 8.16 0.29698   2   0.21 0.0364 7.95, 8.37 -0.3
JUD_EF m 5.6525 1.6005   4 0.80024 0.2831 3.84, 7.39 -0.85
KAV_AF f 14.25 1.4849   2   1.05 0.1042 13.2, 15.3 0.69
KAV_AF m 13.9 0.0   1   0.0 0.0 13.9, 13.9 0.96
LAM_DC f 8.17 0.0   1   0.0 0.0 8.17, 8.17 -0.43
LAM_DC m 11.4 0.0   1   0.0 0.0 11.4, 11.4 0.41
LAT_HD f 5.678 1.1941   5 0.534 0.2103 3.91, 6.92 -0.89
LAT_HD m 8.14 0.52326   2   0.37 0.0643 7.77, 8.51 -0.31
LAX_FC m 6.08 0.08485   2   0.06 0.014 6.02, 6.14 -0.76
LEL_FH m 8.03 0.97581   2   0.69 0.1215 7.34, 8.72 -0.33
LIP_BG f 18.0 3.0078   4 1.5039 0.1671 14.6, 21.9 1.39
LIP_BG m 18.2 0.0   1   0.0 0.0 18.2, 18.2 1.91
LIV_DA f 16.4 0.0   1   0.0 0.0 16.4, 16.4 1.09
LIV_DA m 13.95 0.91924   2   0.65 0.0659 13.3, 14.6 0.97
LOD_AE f 14.933 0.80208   3 0.46308 0.0537 14.1, 15.7 0.82
LOM_BG m 14.5 0.81854   3 0.47258 0.0565 13.6, 15.2 1.1
LOT_FC f 8.9 0.2512   3 0.14503 0.0282 8.75, 9.19 -0.29
LOT_FC m 11.6 6.2225   2   4.4 0.5364 7.2, 16.0 0.46
LOX_GF m 6.4133 0.55148   3 0.3184 0.086 5.84, 6.94 -0.69
LUF_AD m 10.056 3.9737   5 1.7771 0.3952 5.22, 13.5 0.12
LUG_EH m 3.5433 1.4911   3 0.8609 0.4208 2.57, 5.26 -1.32
LUS_AH f 3.32 0.3061   3 0.17673 0.0922 3.0, 3.61 -1.32
LUV_DG m 6.7925 2.1563   4 1.0781 0.3174 4.97, 9.53 -0.6
LUZ_FH f 17.8 3.5355   2   2.5 0.1986 15.3, 20.3 1.35
LUZ_FH m 17.5 0.0   1   0.0 0.0 17.5, 17.5 1.76
MERCURI_HF m 2.0967 0.44377   3 0.25621 0.2117 1.69, 2.57 -1.64
NOD/ShiLtJ f 16.25 3.6062   2   2.55 0.2219 13.7, 18.8 1.06
NOD/ShiLtJ m 14.95 0.49497   2   0.35 0.0331 14.6, 15.3 1.19
NZO/HlLtJ f 8.63 1.9375   2   1.37 0.2245 7.26, 10.0 -0.34
NZO/HlLtJ m 10.455 0.91217   2   0.645 0.0872 9.81, 11.1 0.2
PAT_CD m 4.71 0.13892   3 0.08021 0.0295 4.55, 4.8 -1.06
PEF_EC f 4.67 1.2573   3 0.7259 0.2692 3.31, 5.79 -1.07
PEF_EC m 3.49 0.82018   3 0.47353 0.235 2.66, 4.3 -1.33
POH_DC f 7.91 2.7181   3 1.5693 0.3436 5.27, 10.7 -0.47
PWK/PhJ f 6.025 0.28991   2   0.205 0.0481 5.82, 6.23 -0.82
PWK/PhJ m 6.7 1.4708   2   1.04 0.2195 5.66, 7.74 -0.62
SEH_AH f 20.5 0.0   1   0.0 0.0 20.5, 20.5 1.85
SEH_AH m 15.0 0.0   1   0.0 0.0 15.0, 15.0 1.21
STUCKY_HF f 8.96 0.94027   3 0.54286 0.1049 8.17, 10.0 -0.28
STUCKY_HF m 8.92 0.0   1   0.0 0.0 8.92, 8.92 -0.13
VIT_ED f 26.2 1.2767   3 0.73711 0.0487 24.8, 27.3 2.9
VUX2_HF m 12.0 2.1166   3 1.222 0.1764 10.4, 14.4 0.54
WAD f 9.6733 0.82276   3 0.47502 0.0851 8.78, 10.4 -0.15
WSB/EiJ f 11.95 0.07071   2   0.05 0.0059 11.9, 12.0 0.27
WSB/EiJ m 13.35 1.7678   2   1.25 0.1324 12.1, 14.6 0.84
XAD8_BG f 15.2 0.0   1   0.0 0.0 15.2, 15.2 0.87
XAD8_BG m 13.3 0.88882   3 0.51316 0.0668 12.3, 14.0 0.83
XAH3_GH m 8.5167 1.68   3 0.96995 0.1973 6.84, 10.2 -0.22
XAS4_AF m 8.1233 0.42253   3 0.24395 0.052 7.85, 8.61 -0.31
XAV_AH m 6.77 0.2816   3 0.16258 0.0416 6.56, 7.09 -0.61
XAW2_CD m 7.865 1.0536   2   0.745 0.134 7.12, 8.61 -0.37
XEB2_AG f 5.6 0.49275   3 0.28449 0.088 5.08, 6.06 -0.9
XEB2_AG m 5.6467 0.51013   3 0.29452 0.0903 5.13, 6.15 -0.86
XEB_AF f 8.66 0.91924   2   0.65 0.1061 8.01, 9.31 -0.34
XEB_AF m 9.42 0.0   1   0.0 0.0 9.42, 9.42 -0.02
XEQ_EH m 4.7533 0.58535   3 0.33795 0.1231 4.18, 5.35 -1.05
XXEN2_DC m 8.4933 0.77938   3 0.44998 0.0918 7.85, 9.36 -0.23
XXEN3_DC f 8.36 0.0   1   0.0 0.0 8.36, 8.36 -0.39
XXEN3_DC m 9.1 0.0   1   0.0 0.0 9.1, 9.1 -0.09
YOX_DE m 4.7867 1.3291   3 0.76736 0.2777 3.3, 5.86 -1.05


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 7.4 1.1148 9.661 5.139
129S1/SvImJ m 10.55 1.1148 12.811 8.289
A/J f 5.775 1.1148 8.036 3.514
A/J m 7.125 1.1148 9.386 4.864
CAST/EiJ f 3.32 1.1148 5.581 1.059
CAST/EiJ m 4.075 1.1148 6.336 1.814
CC012/Geni f 4.095 1.1148 6.356 1.834
CC012/Geni m 2.3733 0.9102 4.2194 0.5273
DONNELL_HA f 16.1 1.1148 18.361 13.839
DONNELL_HA m 16.2 0.9102 18.0461 14.3539
LAT_HD f 5.678 0.7051 7.108 4.248
LAT_HD m 8.14 1.1148 10.401 5.879
LOT_FC f 8.9 0.9102 10.7461 7.0539
LOT_FC m 11.6 1.1148 13.861 9.339
NOD/ShiLtJ f 16.25 1.1148 18.511 13.989
NOD/ShiLtJ m 14.95 1.1148 17.211 12.689
NZO/HlLtJ f 8.63 1.1148 10.891 6.369
NZO/HlLtJ m 10.455 1.1148 12.716 8.194
PEF_EC f 4.67 0.9102 6.5161 2.8239
PEF_EC m 3.49 0.9102 5.3361 1.6439
PWK/PhJ f 6.025 1.1148 8.286 3.764
PWK/PhJ m 6.7 1.1148 8.961 4.439
WSB/EiJ f 11.95 1.1148 14.211 9.689
WSB/EiJ m 13.35 1.1148 15.611 11.089
XEB2_AG f 5.6 0.9102 7.4461 3.7539
XEB2_AG m 5.6467 0.9102 7.4927 3.8006


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 8.975 0.7883 10.5737 7.3763
A/J both 6.45 0.7883 8.0487 4.8513
CAST/EiJ both 3.6975 0.7883 5.2962 2.0988
CC012/Geni both 3.2342 0.7196 4.6936 1.7747
DONNELL_HA both 16.15 0.7196 17.6094 14.6906
LAT_HD both 6.909 0.6595 8.2466 5.5714
LOT_FC both 10.25 0.7196 11.7094 8.7906
NOD/ShiLtJ both 15.6 0.7883 17.1987 14.0013
NZO/HlLtJ both 9.5425 0.7883 11.1412 7.9438
PEF_EC both 4.08 0.6436 5.3854 2.7746
PWK/PhJ both 6.3625 0.7883 7.9612 4.7638
WSB/EiJ both 12.65 0.7883 14.2487 11.0513
XEB2_AG both 5.6233 0.6436 6.9287 4.318




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA