Project measure / variable:   McMullan7   VCO2_n_end_MICT

ID, description, units MPD:61625   VCO2_n_end_MICT   mean carbon dioxide production after 4 wks of treatment, during night   [mL/h]  moderate intensity group  
exercise study
Data set, strains McMullan7   CC   4 strains     sex: both     age: 8-10wks
Procedure monitoring system
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  STRAIN COMPARISON PLOT
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McMullan7 - mean carbon dioxide production after 4 wks of treatment, during night moderate intensity group



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested4 strains4 strains
Mean of the strain means3744   mL/h 3245   mL/h
Median of the strain means3784   mL/h 3373   mL/h
SD of the strain means± 390 ± 529
Coefficient of variation (CV)0.104 0.163
Min–max range of strain means3246   –   4162   mL/h 2512   –   3721   mL/h
Mean sample size per strain13.5   mice 9.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3739801.4922 3739801.4922 23.0743 < 0.0001
strain 3 11803379.9276 3934459.9759 24.2753 < 0.0001
sex:strain 3 2534389.0391 844796.3464 5.2123 0.0024
Residuals 84 13614443.8006 162076.7119


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC002/Unc f 3246.0 531.0   16 133.0 0.163 2674.0, 4093.0 -1.28
CC002/Unc m 2512.0 174.0   8 61.7 0.0694 2318.0, 2918.0 -1.39
CC013/GeniUnc f 3908.0 378.0   8 134.0 0.0968 3419.0, 4419.0 0.42
CC013/GeniUnc m 3228.0 227.0   8 80.3 0.0704 2852.0, 3568.0 -0.03
CC027/GeniUnc f 4162.0 397.0   15 102.0 0.0953 3474.0, 4611.0 1.07
CC027/GeniUnc m 3518.0 354.0   11 107.0 0.101 3003.0, 4077.0 0.52
CC037/TauUnc f 3660.0 530.0   15 137.0 0.145 2826.0, 4711.0 -0.22
CC037/TauUnc m 3721.0 208.0   11 62.8 0.056 3420.0, 4036.0 0.9


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC002/Unc f 3246.075 100.6469 3446.2224 3045.9276
CC002/Unc m 2512.2125 142.3362 2795.2636 2229.1614
CC013/GeniUnc f 3907.5875 142.3362 4190.6386 3624.5364
CC013/GeniUnc m 3227.7812 142.3362 3510.8324 2944.7301
CC027/GeniUnc f 4162.02 103.9477 4368.7313 3955.3087
CC027/GeniUnc m 3517.6318 121.3847 3759.0186 3276.245
CC037/TauUnc f 3659.62 103.9477 3866.3313 3452.9087
CC037/TauUnc m 3721.3091 121.3847 3962.6959 3479.9223


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
CC002/Unc both 2879.1437 87.1628 3052.4764 2705.8111
CC013/GeniUnc both 3567.6844 100.6469 3767.8317 3367.537
CC027/GeniUnc both 3839.8259 79.9052 3998.7262 3680.9257
CC037/TauUnc both 3690.4645 79.9052 3849.3648 3531.5643




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA