Project measure / variable:   GMC17   pip_30

ID, description, units MPD:56616   pip_30   auditory brainstem response (ABR) threshold, sound pressure level   [dB]  30 kHz sound stimulus  
Data set, strains GMC17   inbred w/CC7   7 strains     sex: both     age: 17-18wks
Procedure ABR test
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  STRAIN COMPARISON PLOT
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GMC17 - auditory brainstem response (ABR) threshold, sound pressure level 30 kHz sound stimulus



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means74.9   dB 72.5   dB
Median of the strain means80.3   dB 70.0   dB
SD of the strain means± 22.8 ± 20.9
Coefficient of variation (CV)0.305 0.288
Min–max range of strain means45.0   –   100   dB 49.3   –   100   dB
Mean sample size per strain13.0   mice 13.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1162.6374 1162.6374 4.2986 0.0397
strain 6 56785.4575 9464.2429 34.9921 < 0.0001
sex:strain 6 1836.366 306.061 1.1316 0.3461
Residuals 168 45438.6161 270.468


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 65.9 12.7   16 3.17 0.192 45.0, 85.0 -0.39
129S1/SvImJ m 57.2 8.56   16 2.14 0.15 45.0, 75.0 -0.73
A/J f 100.0 0.0   16 0.0 0.0 100.0, 100.0 1.1
A/J m 100.0 0.0   16 0.0 0.0 100.0, 100.0 1.32
C57BL/6J f 85.3 22.2   16 5.56 0.261 30.0, 100.0 0.46
C57BL/6J m 70.0 21.1   16 5.26 0.301 35.0, 100.0 -0.12
CAST/EiJ f 47.5 7.07   8 2.5 0.149 40.0, 60.0 -1.2
CAST/EiJ m 49.3 11.3   7 4.29 0.23 40.0, 70.0 -1.11
NOD/ShiLtJ f 100.0 0.0   17 0.0 0.0 100.0, 100.0 1.1
NOD/ShiLtJ m 100.0 0.0   16 0.0 0.0 100.0, 100.0 1.32
NZO/HlLtJ f 80.3 28.1   16 7.03 0.35 25.0, 100.0 0.24
NZO/HlLtJ m 75.9 31.0   16 7.76 0.409 30.0, 100.0 0.16
WSB/EiJ f 45.0 7.07   2   5.0 0.157 40.0, 50.0 -1.31
WSB/EiJ m 55.0 10.8   4 5.4 0.196 45.0, 70.0 -0.84


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 65.9375 4.1115 74.0543 57.8207
129S1/SvImJ m 57.1875 4.1115 65.3043 49.0707
A/J f 100.0 4.1115 108.1168 91.8832
A/J m 100.0 4.1115 108.1168 91.8832
C57BL/6J f 85.3125 4.1115 93.4293 77.1957
C57BL/6J m 70.0 4.1115 78.1168 61.8832
CAST/EiJ f 47.5 5.8145 58.9789 36.0211
CAST/EiJ m 49.2857 6.216 61.5572 37.0142
NOD/ShiLtJ f 100.0 3.9887 107.8745 92.1255
NOD/ShiLtJ m 100.0 4.1115 108.1168 91.8832
NZO/HlLtJ f 80.3125 4.1115 88.4293 72.1957
NZO/HlLtJ m 75.9375 4.1115 84.0543 67.8207
WSB/EiJ f 45.0 11.629 67.9578 22.0422
WSB/EiJ m 55.0 8.223 71.2336 38.7664


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 61.5625 2.9073 67.302 55.823
A/J both 100.0 2.9073 105.7395 94.2605
C57BL/6J both 77.6563 2.9073 83.3957 71.9168
CAST/EiJ both 48.3929 4.2558 56.7946 39.9912
NOD/ShiLtJ both 100.0 2.8642 105.6544 94.3456
NZO/HlLtJ both 78.125 2.9073 83.8645 72.3855
WSB/EiJ both 50.0 7.1213 64.0587 35.9413




  GWAS USING LINEAR MIXED MODELS