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Project measure / variable:   GMC15   WBC

ID, description, units MPD:56401   WBC   white blood cell count (WBC; per volume x 103)   [n/µL]  
Data set, strains GMC15   inbred w/CC8   8 strains     sex: both     age: 20-21wks
Procedure complete blood count
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  STRAIN COMPARISON PLOT
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GMC15 - white blood cell count (WBC; per volume x 103)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means5.84   n/µL 6.91   n/µL
Median of the strain means7.00   n/µL 6.59   n/µL
SD of the strain means± 2.07 ± 1.49
Coefficient of variation (CV)0.354 0.215
Min–max range of strain means3.03   –   7.80   n/µL 5.35   –   9.18   n/µL
Mean sample size per strain10.1   mice 11.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 44.817 44.817 11.0859 0.0011
strain 7 408.3372 58.3339 14.4295 < 0.0001
sex:strain 7 70.294 10.042 2.484 0.019
Residuals 160 646.8308 4.0427


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 7.38 1.63   10 0.515 0.221 5.2, 10.4 0.74
129S1/SvImJ m 8.62 1.86   12 0.538 0.216 5.0, 11.3 1.15
A/J f 3.31 1.5   10 0.475 0.454 2.0, 7.0 -1.22
A/J m 5.35 1.73   12 0.501 0.324 2.3, 8.0 -1.05
C57BL/6J f 7.43 1.31   10 0.414 0.176 4.8, 9.6 0.77
C57BL/6J m 9.18 3.12   12 0.902 0.34 5.1, 13.9 1.53
CAST/EiJ f 6.83 2.24   12 0.648 0.328 3.9, 11.3 0.48
CAST/EiJ m 7.77 2.19   12 0.632 0.282 4.5, 12.1 0.58
NOD/ShiLtJ f 3.79 0.986   10 0.312 0.26 1.4, 5.1 -0.99
NOD/ShiLtJ m 5.42 1.73   12 0.5 0.32 3.2, 8.2 -1.0
NZO/HlLtJ f 7.16 1.42   10 0.449 0.199 5.3, 9.2 0.64
NZO/HlLtJ m 7.05 1.48   12 0.427 0.21 5.3, 11.1 0.1
PWK/PhJ f 7.8 2.61   10 0.826 0.335 4.3, 12.2 0.95
PWK/PhJ m 6.13 2.6   11 0.785 0.425 1.5, 11.3 -0.52
WSB/EiJ f 3.03 2.2   9 0.733 0.725 0.8, 6.7 -1.36
WSB/EiJ m 5.73 2.1   12 0.607 0.367 2.0, 8.8 -0.79


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 7.38 0.6358 8.6357 6.1243
129S1/SvImJ m 8.6167 0.5804 9.7629 7.4704
A/J f 3.31 0.6358 4.5657 2.0543
A/J m 5.35 0.5804 6.4963 4.2037
C57BL/6J f 7.43 0.6358 8.6857 6.1743
C57BL/6J m 9.1833 0.5804 10.3296 8.0371
CAST/EiJ f 6.8333 0.5804 7.9796 5.6871
CAST/EiJ m 7.7667 0.5804 8.9129 6.6204
NOD/ShiLtJ f 3.79 0.6358 5.0457 2.5343
NOD/ShiLtJ m 5.4167 0.5804 6.5629 4.2704
NZO/HlLtJ f 7.16 0.6358 8.4157 5.9043
NZO/HlLtJ m 7.05 0.5804 8.1963 5.9037
PWK/PhJ f 7.8 0.6358 9.0557 6.5443
PWK/PhJ m 6.1273 0.6062 7.3245 4.93
WSB/EiJ f 3.0333 0.6702 4.3569 1.7097
WSB/EiJ m 5.7333 0.5804 6.8796 4.5871


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 7.9983 0.4305 8.8484 7.1482
A/J both 4.33 0.4305 5.1801 3.4799
C57BL/6J both 8.3067 0.4305 9.1568 7.4566
CAST/EiJ both 7.3 0.4104 8.1105 6.4895
NOD/ShiLtJ both 4.6033 0.4305 5.4534 3.7532
NZO/HlLtJ both 7.105 0.4305 7.9551 6.2549
PWK/PhJ both 6.9636 0.4393 7.8311 6.0961
WSB/EiJ both 4.3833 0.4433 5.2588 3.5078




  GWAS USING LINEAR MIXED MODELS