Project measure / variable:   GMC13   RR

ID, description, units MPD:56211   RR   duration of RR interval   [ms]  
Data set, strains GMC13   inbred   6 strains     sex: both     age: 14-15wks
Procedure ECG
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  STRAIN COMPARISON PLOT
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GMC13 - duration of RR interval



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains6 strains
Mean of the strain means80.7   ms 80.3   ms
Median of the strain means80.8   ms 81.3   ms
SD of the strain means± 4.76 ± 5.24
Coefficient of variation (CV)0.0590 0.0653
Min–max range of strain means72.7   –   85.8   ms 71.1   –   86.3   ms
Mean sample size per strain15.3   mice 14.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 14.1648 14.1648 0.7276 0.3949
strain 5 3712.9561 742.5912 38.1423 < 0.0001
sex:strain 5 104.0884 20.8177 1.0693 0.3793
Residuals 166 3231.8456 19.4689


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 85.8 4.43   16 1.11 0.0516 80.1, 96.7 1.08
129S1/SvImJ m 86.3 4.15   16 1.04 0.048 78.0, 96.3 1.15
A/J f 85.1 9.18   16 2.3 0.108 74.9, 112.0 0.93
A/J m 82.9 4.84   16 1.21 0.0584 74.9, 92.9 0.5
C57BL/6J f 81.2 3.09   16 0.773 0.0381 76.8, 90.8 0.11
C57BL/6J m 79.8 2.33   16 0.582 0.0292 75.8, 83.4 -0.09
NOD/ShiLtJ f 78.8 5.55   12 1.6 0.0704 74.1, 92.8 -0.4
NOD/ShiLtJ m 78.6 1.77   12 0.512 0.0226 75.5, 82.7 -0.32
NZO/HlLtJ f 80.5 3.07   17 0.745 0.0382 75.6, 86.5 -0.04
NZO/HlLtJ m 82.9 3.48   11 1.05 0.042 76.5, 88.0 0.5
PWK/PhJ f 72.7 2.93   15 0.758 0.0404 67.4, 77.7 -1.68
PWK/PhJ m 71.1 2.27   15 0.587 0.032 67.5, 75.1 -1.75


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 85.8438 1.1031 88.0216 83.6659
129S1/SvImJ m 86.35 1.1031 88.5279 84.1721
A/J f 85.0813 1.1031 87.2591 82.9034
A/J m 82.9063 1.1031 85.0841 80.7284
C57BL/6J f 81.2125 1.1031 83.3904 79.0346
C57BL/6J m 79.7563 1.1031 81.9341 77.5784
NOD/ShiLtJ f 78.8333 1.2737 81.3482 76.3185
NOD/ShiLtJ m 78.6083 1.2737 81.1232 76.0935
NZO/HlLtJ f 80.4824 1.0702 82.5952 78.3695
NZO/HlLtJ m 82.8818 1.3304 85.5085 80.2552
PWK/PhJ f 72.7067 1.1393 74.956 70.4573
PWK/PhJ m 71.0733 1.1393 73.3227 68.824


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 86.0969 0.78 87.6369 84.5569
A/J both 83.9938 0.78 85.5338 82.4537
C57BL/6J both 80.4844 0.78 82.0244 78.9444
NOD/ShiLtJ both 78.7208 0.9007 80.4991 76.9426
NZO/HlLtJ both 81.6821 0.8537 83.3676 79.9966
PWK/PhJ both 71.89 0.8056 73.4805 70.2995




  GWAS USING LINEAR MIXED MODELS