Project measure / variable:   GMC12   heart_rate

ID, description, units MPD:56112   heart_rate   heart rate, beats per min   [n/min]  
Data set, strains GMC12   inbred w/CC8   8 strains     sex: both     age: 14-15wks
Procedure echocardiography
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  STRAIN COMPARISON PLOT
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GMC12 - heart rate, beats per min



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means617   n/min 635   n/min
Median of the strain means648   n/min 663   n/min
SD of the strain means± 159 ± 106
Coefficient of variation (CV)0.257 0.167
Min–max range of strain means239   –   731   n/min 457   –   787   n/min
Mean sample size per strain17.1   mice 16.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 16120.3232 16120.3232 1.3235 0.251
strain 7 4065361.9195 580765.9885 47.683 < 0.0001
sex:strain 7 608098.068 86871.1526 7.1324 < 0.0001
Residuals 252 3069292.8158 12179.7334


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 632.0 72.6   16 18.2 0.115 389.0, 713.0 0.09
129S1/SvImJ m 521.0 146.0   16 36.6 0.281 273.0, 658.0 -1.07
A/J f 665.0 80.9   15 20.9 0.122 417.0, 775.0 0.3
A/J m 662.0 115.0   16 28.8 0.174 380.0, 837.0 0.26
C57BL/6J f 621.0 140.0   16 34.9 0.225 242.0, 727.0 0.02
C57BL/6J m 664.0 95.3   16 23.8 0.144 379.0, 779.0 0.27
CAST/EiJ f 731.0 68.5   19 15.7 0.0938 534.0, 836.0 0.72
CAST/EiJ m 685.0 69.7   14 18.6 0.102 545.0, 754.0 0.47
NOD/ShiLtJ f 703.0 64.3   18 15.2 0.0915 581.0, 827.0 0.54
NOD/ShiLtJ m 708.0 32.1   16 8.03 0.0453 660.0, 778.0 0.69
NZO/HlLtJ f 629.0 95.3   17 23.1 0.151 442.0, 762.0 0.07
NZO/HlLtJ m 595.0 146.0   17 35.4 0.245 163.0, 750.0 -0.38
PWK/PhJ f 239.0 145.0   19 33.3 0.606 124.0, 584.0 -2.38
PWK/PhJ m 457.0 181.0   20 40.4 0.395 172.0, 783.0 -1.68
WSB/EiJ f 717.0 109.0   17 26.5 0.152 478.0, 837.0 0.63
WSB/EiJ m 787.0 50.7   16 12.7 0.0645 706.0, 857.0 1.43


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 631.8787 27.5905 686.216 577.5415
129S1/SvImJ m 520.95 27.5905 575.2873 466.6127
A/J f 665.4887 28.4953 721.608 609.3694
A/J m 662.0581 27.5905 716.3954 607.7209
C57BL/6J f 620.58 27.5905 674.9173 566.2427
C57BL/6J m 664.3575 27.5905 718.6948 610.0202
CAST/EiJ f 730.8532 25.3187 780.7165 680.9899
CAST/EiJ m 685.3936 29.4954 743.4825 627.3046
NOD/ShiLtJ f 702.6733 26.0125 753.903 651.4437
NOD/ShiLtJ m 707.995 27.5905 762.3323 653.6577
NZO/HlLtJ f 629.3376 26.7667 682.0525 576.6228
NZO/HlLtJ m 595.4653 26.7667 648.1802 542.7504
PWK/PhJ f 239.4616 25.3187 289.3249 189.5983
PWK/PhJ m 457.115 24.6777 505.7157 408.5143
WSB/EiJ f 716.5941 26.7667 769.309 663.8792
WSB/EiJ m 787.1481 27.5905 841.4854 732.8109


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 576.4144 19.5094 614.8366 537.9921
A/J both 663.7734 19.8319 702.8308 624.716
C57BL/6J both 642.4687 19.5094 680.891 604.0465
CAST/EiJ both 708.1234 19.4359 746.4009 669.8458
NOD/ShiLtJ both 705.3342 18.9597 742.6739 667.9945
NZO/HlLtJ both 612.4015 18.9269 649.6765 575.1264
PWK/PhJ both 348.2883 17.6778 383.1034 313.4731
WSB/EiJ both 751.8711 19.2204 789.7241 714.0181




  GWAS USING LINEAR MIXED MODELS