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Project measure / variable:   GMC05   ASR_ISI_5

ID, description, units MPD:55441   ASR_ISI_5   acoustic startle response (ASR)   [amplitude]  PP2 inter-stimulus interval: 5  
Data set, strains GMC05   inbred w/CC8   8 strains     sex: both     age: 9-10wks
Procedure acoustic startle test
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  STRAIN COMPARISON PLOT
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GMC05 - acoustic startle response (ASR) PP2 inter-stimulus interval: 5



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means498   amplitude 599   amplitude
Median of the strain means310   amplitude 424   amplitude
SD of the strain means± 629 ± 612
Coefficient of variation (CV)1.26 1.02
Min–max range of strain means149   –   2042   amplitude 223   –   2094   amplitude
Mean sample size per strain16.9   mice 16.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 780801.0222 780801.0222 8.5864 0.0037
strain 7 86422841.1479 12346120.164 135.7697 < 0.0001
sex:strain 7 319262.9422 45608.9917 0.5016 0.833
Residuals 250 22733564.3681 90934.2575


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 318.0 182.0   16 45.5 0.572 144.0, 848.0 -0.29
129S1/SvImJ m 499.0 265.0   16 66.3 0.531 235.0, 1243.0 -0.16
A/J f 208.0 177.0   16 44.3 0.851 75.9, 804.0 -0.46
A/J m 223.0 157.0   16 39.2 0.704 77.0, 729.0 -0.61
C57BL/6J f 215.0 94.4   16 23.6 0.439 98.1, 448.0 -0.45
C57BL/6J m 424.0 136.0   16 33.9 0.32 212.0, 683.0 -0.29
CAST/EiJ f 302.0 81.9   19 18.8 0.271 160.0, 436.0 -0.31
CAST/EiJ m 456.0 97.2   18 22.9 0.213 302.0, 604.0 -0.23
NOD/ShiLtJ f 149.0 62.0   18 14.6 0.415 75.1, 289.0 -0.55
NOD/ShiLtJ m 250.0 148.0   16 37.1 0.593 83.6, 675.0 -0.57
NZO/HlLtJ f 2042.0 754.0   16 188.0 0.369 809.0, 3172.0 2.45
NZO/HlLtJ m 2094.0 815.0   16 204.0 0.389 960.0, 3093.0 2.44
PWK/PhJ f 339.0 67.2   16 16.8 0.198 240.0, 469.0 -0.25
PWK/PhJ m 425.0 135.0   17 32.8 0.318 204.0, 709.0 -0.28
WSB/EiJ f 410.0 93.7   18 22.1 0.229 293.0, 659.0 -0.14
WSB/EiJ m 422.0 133.0   16 33.1 0.314 246.0, 652.0 -0.29


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 318.2688 75.3883 466.7458 169.7917
129S1/SvImJ m 499.35 75.3883 647.8271 350.8729
A/J f 208.0938 75.3883 356.5708 59.6167
A/J m 222.7938 75.3883 371.2708 74.3167
C57BL/6J f 215.2938 75.3883 363.7708 66.8167
C57BL/6J m 424.1625 75.3883 572.6396 275.6854
CAST/EiJ f 302.0158 69.181 438.2677 165.7639
CAST/EiJ m 456.1278 71.0767 596.1133 316.1422
NOD/ShiLtJ f 149.4611 71.0767 289.4466 9.4756
NOD/ShiLtJ m 250.1125 75.3883 398.5896 101.6354
NZO/HlLtJ f 2042.4938 75.3883 2190.9708 1894.0167
NZO/HlLtJ m 2093.6563 75.3883 2242.1333 1945.1792
PWK/PhJ f 338.7938 75.3883 487.2708 190.3167
PWK/PhJ m 424.9588 73.1374 569.0027 280.9149
WSB/EiJ f 409.8889 71.0767 549.8744 269.9034
WSB/EiJ m 421.5938 75.3883 570.0708 273.1167


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 408.8094 53.3076 513.7985 303.8202
A/J both 215.4438 53.3076 320.4329 110.4546
C57BL/6J both 319.7281 53.3076 424.7173 214.739
CAST/EiJ both 379.0718 49.5931 476.7454 281.3982
NOD/ShiLtJ both 199.7868 51.8056 301.8179 97.7557
NZO/HlLtJ both 2068.075 53.3076 2173.0641 1963.0859
PWK/PhJ both 381.8763 52.5178 485.31 278.4426
WSB/EiJ both 415.7413 51.8056 517.7724 313.7102




  GWAS USING LINEAR MIXED MODELS