Project measure / variable:   GMC05   ASR_100

ID, description, units MPD:55416   ASR_100   acoustic startle response (ASR)   [amplitude]  evoked by 100 dB  
Data set, strains GMC05   inbred w/CC8   8 strains     sex: both     age: 9-10wks
Procedure acoustic startle test
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  STRAIN COMPARISON PLOT
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GMC05 - acoustic startle response (ASR) evoked by 100 dB



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means620   amplitude 807   amplitude
Median of the strain means434   amplitude 557   amplitude
SD of the strain means± 642 ± 743
Coefficient of variation (CV)1.04 0.920
Min–max range of strain means83.0   –   2093   amplitude 94.9   –   2303   amplitude
Mean sample size per strain16.9   mice 16.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2449395.9125 2449395.9125 46.1608 < 0.0001
strain 7 106028040.4212 15146862.9173 285.4547 < 0.0001
sex:strain 7 2899136.9761 414162.4252 7.8052 < 0.0001
Residuals 250 13265557.1248 53062.2285


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 851.0 311.0   16 77.7 0.365 454.0, 1532.0 0.36
129S1/SvImJ m 1348.0 301.0   16 75.2 0.223 731.0, 1825.0 0.73
A/J f 83.0 47.5   16 11.9 0.572 37.7, 238.0 -0.84
A/J m 94.9 50.0   16 12.5 0.527 36.8, 212.0 -0.96
C57BL/6J f 531.0 269.0   16 67.1 0.506 244.0, 1311.0 -0.14
C57BL/6J m 1095.0 223.0   16 55.7 0.203 546.0, 1511.0 0.39
CAST/EiJ f 336.0 82.0   19 18.8 0.244 195.0, 506.0 -0.44
CAST/EiJ m 504.0 144.0   18 33.8 0.284 258.0, 740.0 -0.41
NOD/ShiLtJ f 241.0 126.0   18 29.6 0.52 74.4, 466.0 -0.59
NOD/ShiLtJ m 230.0 162.0   16 40.6 0.704 109.0, 700.0 -0.78
NZO/HlLtJ f 2093.0 461.0   16 115.0 0.22 1310.0, 3047.0 2.3
NZO/HlLtJ m 2303.0 482.0   16 120.0 0.209 1312.0, 3237.0 2.01
PWK/PhJ f 251.0 80.8   16 20.2 0.322 179.0, 461.0 -0.57
PWK/PhJ m 275.0 64.5   17 15.6 0.234 198.0, 472.0 -0.72
WSB/EiJ f 572.0 133.0   18 31.4 0.233 257.0, 815.0 -0.07
WSB/EiJ m 610.0 139.0   16 34.8 0.228 287.0, 851.0 -0.27


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 851.025 57.5881 964.4447 737.6053
129S1/SvImJ m 1348.4875 57.5881 1461.9072 1235.0678
A/J f 83.0438 57.5881 196.4634 -30.3759
A/J m 94.9438 57.5881 208.3634 -18.4759
C57BL/6J f 531.0375 57.5881 644.4572 417.6178
C57BL/6J m 1095.3813 57.5881 1208.8009 981.9616
CAST/EiJ f 335.9526 52.8465 440.0337 231.8716
CAST/EiJ m 504.4778 54.2946 611.4109 397.5447
NOD/ShiLtJ f 241.1833 54.2946 348.1164 134.2502
NOD/ShiLtJ m 230.475 57.5881 343.8947 117.0553
NZO/HlLtJ f 2092.7125 57.5881 2206.1322 1979.2928
NZO/HlLtJ m 2302.7375 57.5881 2416.1572 2189.3178
PWK/PhJ f 250.6937 57.5881 364.1134 137.2741
PWK/PhJ m 275.4059 55.8687 385.4391 165.3726
WSB/EiJ f 571.8667 54.2946 678.7998 464.9336
WSB/EiJ m 609.7063 57.5881 723.1259 496.2866


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1099.7563 40.7209 1179.9561 1019.5564
A/J both 88.9938 40.7209 169.1936 8.7939
C57BL/6J both 813.2094 40.7209 893.4092 733.0096
CAST/EiJ both 420.2152 37.8835 494.8268 345.6036
NOD/ShiLtJ both 235.8292 39.5736 313.7694 157.889
NZO/HlLtJ both 2197.725 40.7209 2277.9248 2117.5252
PWK/PhJ both 263.0498 40.1176 342.0614 184.0382
WSB/EiJ both 590.7865 39.5736 668.7267 512.8462




  GWAS USING LINEAR MIXED MODELS