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Project measure / variable:   GMC02   all_paws_adj

ID, description, units MPD:55125   all_paws_adj   forelimb and hindlimb grip strength (mean) normalized to body weight   [ratio]  
Data set, strains GMC02   inbred w/CC8   8 strains     sex: both     age: 8-10wks
Procedure grip strength
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  STRAIN COMPARISON PLOT
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GMC02 - forelimb and hindlimb grip strength (mean) normalized to body weight



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means9.99   ratio 8.95   ratio
Median of the strain means10.7   ratio 9.48   ratio
SD of the strain means± 2.23 ± 1.74
Coefficient of variation (CV)0.223 0.195
Min–max range of strain means5.14   –   12.3   ratio 4.81   –   10.1   ratio
Mean sample size per strain17.4   mice 16.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 80.93 80.93 49.1838 < 0.0001
strain 7 931.7162 133.1023 80.8907 < 0.0001
sex:strain 7 37.652 5.3789 3.2689 0.0024
Residuals 258 424.5286 1.6455


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 8.52 0.803   16 0.201 0.0942 7.54, 10.6 -0.66
129S1/SvImJ m 8.76 0.866   16 0.217 0.0989 6.77, 10.3 -0.11
A/J f 10.6 1.71   16 0.429 0.162 7.97, 13.5 0.27
A/J m 9.64 1.09   16 0.273 0.113 7.74, 11.5 0.4
C57BL/6J f 11.2 1.61   16 0.403 0.144 8.23, 13.9 0.54
C57BL/6J m 9.33 1.32   16 0.33 0.141 7.93, 11.7 0.22
CAST/EiJ f 12.3 1.27   19 0.291 0.103 10.2, 14.6 1.03
CAST/EiJ m 10.1 1.21   17 0.294 0.12 7.43, 12.6 0.66
NOD/ShiLtJ f 10.3 1.4   18 0.33 0.136 8.08, 12.4 0.14
NOD/ShiLtJ m 8.97 0.924   16 0.231 0.103 6.73, 10.2 0.01
NZO/HlLtJ f 5.14 0.606   17 0.147 0.118 4.47, 6.85 -2.18
NZO/HlLtJ m 4.81 0.421   17 0.102 0.0876 4.26, 5.61 -2.37
PWK/PhJ f 11.1 1.57   19 0.361 0.141 8.56, 13.8 0.5
PWK/PhJ m 9.96 1.44   21 0.315 0.145 7.77, 12.3 0.58
WSB/EiJ f 10.8 1.62   18 0.382 0.15 7.46, 13.5 0.36
WSB/EiJ m 10.0 1.6   16 0.4 0.159 6.39, 13.2 0.6


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 8.5244 0.3207 9.1559 7.8929
129S1/SvImJ m 8.7619 0.3207 9.3934 8.1304
A/J f 10.57 0.3207 11.2015 9.9385
A/J m 9.645 0.3207 10.2765 9.0135
C57BL/6J f 11.1994 0.3207 11.8309 10.5679
C57BL/6J m 9.335 0.3207 9.9665 8.7035
CAST/EiJ f 12.3311 0.2943 12.9106 11.7515
CAST/EiJ m 10.08 0.3111 10.6926 9.4674
NOD/ShiLtJ f 10.3072 0.3023 10.9026 9.7118
NOD/ShiLtJ m 8.9737 0.3207 9.6053 8.3422
NZO/HlLtJ f 5.1388 0.3111 5.7515 4.5262
NZO/HlLtJ m 4.8088 0.3111 5.4215 4.1962
PWK/PhJ f 11.1258 0.2943 11.7053 10.5463
PWK/PhJ m 9.961 0.2799 10.5122 9.4097
WSB/EiJ f 10.7911 0.3023 11.3865 10.1957
WSB/EiJ m 10.05 0.3207 10.6815 9.4185


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 8.6431 0.2268 9.0897 8.1966
A/J both 10.1075 0.2268 10.554 9.661
C57BL/6J both 10.2672 0.2268 10.7137 9.8206
CAST/EiJ both 11.2055 0.2141 11.6272 10.7839
NOD/ShiLtJ both 9.6405 0.2204 10.0744 9.2065
NZO/HlLtJ both 4.9738 0.22 5.407 4.5406
PWK/PhJ both 10.5434 0.2031 10.9433 10.1435
WSB/EiJ both 10.4206 0.2204 10.8545 9.9866




  GWAS USING LINEAR MIXED MODELS