Project measure / variable:   Nadeau2   CHOL

ID, description, units MPD:53041   CHOL   total cholesterol (plasma CHOL)   [mmol/L]  
high-fat high-sucrose diet study
Data set, strains Nadeau2   B6.A consomic w/par   24 strains     sex: m     age: 21wks
Procedure lipid profile
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  STRAIN COMPARISON PLOT
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Nadeau2 - total cholesterol (plasma CHOL)



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested24 strains
Mean of the strain means3.97   mmol/L
Median of the strain means3.97   mmol/L
SD of the strain means± 0.489
Coefficient of variation (CV)0.123
Min–max range of strain means2.91   –   4.88   mmol/L
Mean sample size per strain39.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 23 270.0601 11.7417 34.7595 < 0.0001
Residuals 954 322.2609 0.3378


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J m 2.91 0.304   95 0.0312 0.105 2.31, 3.77 -2.17
B6.A-Chr1 m 4.88 0.851   27 0.164 0.175 2.11, 5.95 1.86
B6.A-Chr10 m 3.46 0.601   76 0.0689 0.174 2.16, 4.68 -1.05
B6.A-Chr11 m 4.11 0.691   36 0.115 0.168 2.55, 5.23 0.28
B6.A-Chr12 m 3.77 0.591   35 0.1 0.157 2.39, 4.99 -0.41
B6.A-Chr13 m 3.82 0.68   27 0.131 0.178 1.95, 4.47 -0.31
B6.A-Chr14 m 4.22 0.544   34 0.0933 0.129 3.28, 5.38 0.51
B6.A-Chr15 m 3.39 0.447   27 0.086 0.132 2.39, 4.26 -1.19
B6.A-Chr16 m 4.11 0.506   37 0.0833 0.123 2.89, 5.15 0.28
B6.A-Chr17 m 3.91 0.548   36 0.0913 0.14 2.63, 4.84 -0.13
B6.A-Chr18 m 4.68 0.54   38 0.0877 0.116 3.41, 5.77 1.45
B6.A-Chr19 m 4.63 0.68   34 0.117 0.147 2.78, 6.08 1.35
B6.A-Chr2 m 4.36 0.627   34 0.108 0.144 3.25, 5.69 0.79
B6.A-Chr3 m 3.59 0.716   40 0.113 0.2 2.24, 4.81 -0.78
B6.A-Chr4 m 3.24 0.423   38 0.0686 0.131 2.13, 4.13 -1.5
B6.A-Chr5 m 4.03 0.516   38 0.0837 0.128 2.86, 5.12 0.12
B6.A-Chr6 m 3.74 0.334   38 0.0542 0.0894 2.7, 4.32 -0.47
B6.A-Chr7 m 3.89 0.584   34 0.1 0.15 3.04, 5.28 -0.17
B6.A-Chr8 m 3.47 0.528   34 0.0905 0.152 1.9, 4.71 -1.03
B6.A-Chr9 m 4.38 0.441   33 0.0767 0.101 3.67, 5.54 0.83
B6.A-ChrX m 4.56 0.543   36 0.0905 0.119 3.3, 5.67 1.2
B6.A-ChrY m 4.03 0.586   31 0.105 0.145 2.83, 4.86 0.12
B6.A-mt m 3.79 0.541   24 0.11 0.143 2.91, 4.63 -0.37
C57BL/6J m 4.36 0.786   96 0.0802 0.18 2.42, 6.03 0.79


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 2.9088 0.0596 3.0259 2.7918
B6.A-Chr1 m 4.8752 0.1119 5.0947 4.6557
B6.A-Chr10 m 3.4557 0.0667 3.5865 3.3248
B6.A-Chr11 m 4.1064 0.0969 4.2965 3.9163
B6.A-Chr12 m 3.7697 0.0982 3.9625 3.5769
B6.A-Chr13 m 3.8248 0.1119 4.0443 3.6053
B6.A-Chr14 m 4.2171 0.0997 4.4127 4.0214
B6.A-Chr15 m 3.3885 0.1119 3.608 3.169
B6.A-Chr16 m 4.1065 0.0955 4.294 3.919
B6.A-Chr17 m 3.9094 0.0969 4.0995 3.7193
B6.A-Chr18 m 4.6784 0.0943 4.8634 4.4934
B6.A-Chr19 m 4.6344 0.0997 4.83 4.4388
B6.A-Chr2 m 4.3574 0.0997 4.553 4.1617
B6.A-Chr3 m 3.5882 0.0919 3.7686 3.4079
B6.A-Chr4 m 3.2368 0.0943 3.4219 3.0518
B6.A-Chr5 m 4.0316 0.0943 4.2166 3.8466
B6.A-Chr6 m 3.7355 0.0943 3.9206 3.5505
B6.A-Chr7 m 3.8874 0.0997 4.083 3.6917
B6.A-Chr8 m 3.4679 0.0997 3.6636 3.2723
B6.A-Chr9 m 4.3758 0.1012 4.5743 4.1772
B6.A-ChrX m 4.5647 0.0969 4.7548 4.3746
B6.A-ChrY m 4.0332 0.1044 4.2381 3.8284
B6.A-mt m 3.7875 0.1186 4.0203 3.5547
C57BL/6J m 4.3609 0.0593 4.4773 4.2445




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA