Project measure / variable:   Wiltshire4   Tcells_Dox_E

ID, description, units MPD:52432   Tcells_Dox_E   T cells, percent viability   [%]  dose: 100 µM  
doxorubicin study
Data set, strains Wiltshire4   inbred w/CC7   35 strains     sex: m     age: 10wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Wiltshire4 - T cells, percent viability dose: 100 µM



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested35 strains
Mean of the strain means65.3   %
Median of the strain means72.8   %
SD of the strain means± 28.7
Coefficient of variation (CV)0.439
Min–max range of strain means2.20   –   113   %
Mean sample size per strain3.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 33 91319.2201 2767.2491 25.1119 < 0.0001
Residuals 99 10909.4798 110.1968


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 67.6 20.7   4 10.3 0.306 37.8, 84.5 0.08
129X1/SvJ m 90.0 6.02   4 3.01 0.0668 83.1, 96.2 0.86
A/J m 90.9 2.92   4 1.46 0.0321 86.7, 93.1 0.89
AKR/J m 92.2 5.69   4 2.84 0.0616 85.2, 97.3 0.94
BALB/cByJ m 82.6 3.27   4 1.64 0.0396 77.7, 84.8 0.6
BTBR T+ Itpr3tf/J m 60.9 7.19   4 3.6 0.118 52.5, 67.5 -0.15
C3H/HeJ m 81.7 4.76   4 2.38 0.0583 77.3, 87.6 0.57
C57BL/6J m 75.5 28.4   4 14.2 0.377 32.9, 90.5 0.36
C57BLKS/J m 93.1 2.98   4 1.49 0.032 90.5, 96.4 0.97
C57BR/cdJ m 99.3 1.85   4 0.926 0.0187 97.1, 102.0 1.19
C58/J m 21.8 6.92   2   4.9 0.317 16.9, 26.7 -1.52
CBA/J m 91.5 8.36   4 4.18 0.0913 80.0, 98.5 0.91
CZECHII/EiJ m 55.2 20.9   4 10.5 0.379 30.1, 80.5 -0.35
DBA/2J m 88.8 7.06   4 3.53 0.0794 81.9, 97.8 0.82
FVB/NJ m 94.4 2.6   4 1.3 0.0276 91.5, 97.1 1.02
I/LnJ m 2.2 0.0   1   0.0 0.0 2.2, 2.2 -2.2
KK/HlJ m 22.0 5.48   4 2.74 0.249 13.9, 25.6 -1.51
LG/J m 55.8 18.0   4 8.98 0.322 32.1, 71.4 -0.33
LP/J m 72.8 6.23   4 3.11 0.0855 66.2, 81.2 0.26
MA/MyJ m 37.0 8.89   4 4.45 0.241 31.0, 49.8 -0.99
NOD/ShiLtJ m 49.5 7.24   4 3.62 0.146 40.7, 58.2 -0.55
NON/ShiLtJ m 64.2 7.73   4 3.86 0.12 55.2, 74.1 -0.04
NZB/BlNJ m 85.2 6.05   4 3.03 0.0711 76.3, 89.5 0.7
NZO/HlLtJ m 75.0 10.0   4 5.01 0.134 60.3, 82.9 0.34
NZW/LacJ m 15.8 3.89   4 1.95 0.247 10.6, 19.5 -1.72
PERA/EiJ m 5.27 1.04   4 0.518 0.197 4.0, 6.54 -2.09
PL/J m 61.9 9.39   4 4.7 0.152 53.9, 73.9 -0.12
PWD/PhJ m 74.9 8.25   4 4.12 0.11 65.5, 83.7 0.34
PWK/PhJ m 43.8 10.7   4 5.34 0.244 30.8, 56.4 -0.75
RIIIS/J m 34.3 13.5   4 6.73 0.392 19.9, 48.9 -1.08
SEA/GnJ m 95.6 2.26   4 1.13 0.0237 92.9, 98.2 1.06
SJL/J m 82.8 13.6   4 6.79 0.164 67.3, 97.4 0.61
SM/J m 39.9 3.93   4 1.96 0.0985 36.4, 45.1 -0.88
SWR/J m 113.0 7.11   4 3.55 0.0629 104.0, 121.0 1.66
WSB/EiJ m 67.7 17.4   3 10.0 0.257 56.2, 87.7 0.09


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 67.6075 5.2487 78.0221 57.1929
129X1/SvJ m 89.9825 5.2487 100.3971 79.5679
A/J m 90.8775 5.2487 101.2921 80.4629
AKR/J m 92.2325 5.2487 102.6471 81.8179
BALB/cByJ m 82.5875 5.2487 93.0021 72.1729
BTBR T+ Itpr3tf/J m 60.8925 5.2487 71.3071 50.4779
C3H/HeJ m 81.67 5.2487 92.0846 71.2554
C57BL/6J m 75.52 5.2487 85.9346 65.1054
C57BLKS/J m 93.08 5.2487 103.4946 82.6654
C57BR/cdJ m 99.2525 5.2487 109.6671 88.8379
C58/J m 21.815 7.4228 36.5435 7.0865
CBA/J m 91.54 5.2487 101.9546 81.1254
CZECHII/EiJ m 55.25 5.2487 65.6646 44.8354
DBA/2J m 88.84 5.2487 99.2546 78.4254
FVB/NJ m 94.42 5.2487 104.8346 84.0054
KK/HlJ m 22.035 5.2487 32.4496 11.6204
LG/J m 55.82 5.2487 66.2346 45.4054
LP/J m 72.79 5.2487 83.2046 62.3754
MA/MyJ m 36.955 5.2487 47.3696 26.5404
NOD/ShiLtJ m 49.47 5.2487 59.8846 39.0554
NON/ShiLtJ m 64.1875 5.2487 74.6021 53.7729
NZB/BlNJ m 85.1775 5.2487 95.5921 74.7629
NZO/HlLtJ m 75.0225 5.2487 85.4371 64.6079
NZW/LacJ m 15.7775 5.2487 26.1921 5.3629
PERA/EiJ m 5.2675 5.2487 15.6821 0.0
PL/J m 61.9175 5.2487 72.3321 51.5029
PWD/PhJ m 74.86 5.2487 85.2746 64.4454
PWK/PhJ m 43.78 5.2487 54.1946 33.3654
RIIIS/J m 34.31 5.2487 44.7246 23.8954
SEA/GnJ m 95.6 5.2487 106.0146 85.1854
SJL/J m 82.7725 5.2487 93.1871 72.3579
SM/J m 39.895 5.2487 50.3096 29.4804
SWR/J m 112.955 5.2487 123.3696 102.5404
WSB/EiJ m 67.6567 6.0607 79.6824 55.6309




  GWAS USING LINEAR MIXED MODELS