Project measure / variable:   Wiltshire4   Tcells_BEZ_E

ID, description, units MPD:52412   Tcells_BEZ_E   T cells, percent viability   [%]  dose: 100 µM  
BEZ235 study
Data set, strains Wiltshire4   inbred w/CC7   34 strains     sex: m     age: 10wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Wiltshire4 - T cells, percent viability dose: 100 µM



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested34 strains
Mean of the strain means97.0   %
Median of the strain means97.0   %
SD of the strain means± 6.88
Coefficient of variation (CV)0.0709
Min–max range of strain means80.3   –   118   %
Mean sample size per strain4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 33 5818.581 176.3206 6.7112 < 0.0001
Residuals 99 2600.9885 26.2726


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 99.9 1.09   4 0.543 0.0109 98.8, 101.0 0.42
129X1/SvJ m 96.2 5.87   4 2.94 0.061 88.8, 103.0 -0.12
A/J m 97.8 2.14   4 1.07 0.0219 95.1, 99.5 0.12
AKR/J m 96.9 1.56   4 0.778 0.016 94.9, 98.5 -0.01
BALB/cByJ m 99.4 1.94   4 0.968 0.0195 96.7, 101.0 0.35
BTBR T+ Itpr3tf/J m 96.3 4.63   4 2.32 0.0481 90.0, 100.0 -0.1
BUB/BnJ m 93.6 2.72   4 1.36 0.029 89.6, 95.8 -0.49
C3H/HeJ m 97.8 1.03   4 0.516 0.0106 96.7, 98.8 0.12
C57BL/6J m 95.0 6.88   4 3.44 0.0724 84.7, 98.8 -0.29
C57BLKS/J m 101.0 2.2   4 1.1 0.0219 97.4, 102.0 0.58
C58/J m 103.0 5.82   2   4.12 0.0563 99.2, 107.0 0.87
CBA/J m 103.0 4.28   4 2.14 0.0415 99.0, 107.0 0.87
CZECHII/EiJ m 94.5 2.98   4 1.49 0.0315 91.0, 98.3 -0.36
DBA/2J m 89.4 6.48   4 3.24 0.0725 79.8, 94.1 -1.1
FVB/NJ m 98.3 0.877   4 0.439 0.00892 97.6, 99.6 0.19
I/LnJ m 98.4 0.902   4 0.451 0.00916 97.3, 99.3 0.2
KK/HlJ m 90.9 2.61   4 1.31 0.0287 88.2, 94.4 -0.89
LG/J m 112.0 11.4   4 5.68 0.101 96.6, 121.0 2.18
LP/J m 94.9 3.35   4 1.68 0.0353 89.9, 96.9 -0.3
MA/MyJ m 92.7 5.66   4 2.83 0.061 85.3, 99.1 -0.62
NOD/ShiLtJ m 101.0 2.46   4 1.23 0.0244 97.9, 104.0 0.58
NON/ShiLtJ m 97.9 6.1   4 3.05 0.0623 93.3, 107.0 0.13
NZB/BlNJ m 97.1 1.32   4 0.658 0.0136 95.3, 98.3 0.02
NZO/HlLtJ m 92.4 8.41   4 4.2 0.091 80.9, 100.0 -0.67
NZW/LacJ m 96.7 4.67   4 2.34 0.0483 91.7, 103.0 -0.04
PERA/EiJ m 104.0 6.29   4 3.15 0.0605 95.2, 110.0 1.02
PL/J m 99.5 3.49   4 1.75 0.0351 94.3, 102.0 0.36
PWD/PhJ m 87.9 9.05   4 4.53 0.103 81.7, 101.0 -1.32
PWK/PhJ m 98.0 6.56   4 3.28 0.0669 88.2, 102.0 0.15
RIIIS/J m 83.4 10.3   4 5.17 0.124 77.2, 98.8 -1.98
SEA/GnJ m 95.0 3.62   4 1.81 0.0381 90.0, 98.6 -0.29
SJL/J m 80.3 4.77   4 2.39 0.0594 75.8, 86.5 -2.43
SM/J m 95.6 1.93   4 0.966 0.0202 94.4, 98.5 -0.2
WSB/EiJ m 118.0 5.03   3 2.9 0.0424 113.0, 122.0 3.05


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 99.8625 2.5628 104.9477 94.7773
129X1/SvJ m 96.1825 2.5628 101.2677 91.0973
A/J m 97.8175 2.5628 102.9027 92.7323
AKR/J m 96.91 2.5628 101.9952 91.8248
BALB/cByJ m 99.36 2.5628 104.4452 94.2748
BTBR T+ Itpr3tf/J m 96.3375 2.5628 101.4227 91.2523
BUB/BnJ m 93.565 2.5628 98.6502 88.4798
C3H/HeJ m 97.775 2.5628 102.8602 92.6898
C57BL/6J m 94.98 2.5628 100.0652 89.8948
C57BLKS/J m 100.5625 2.5628 105.6477 95.4773
C58/J m 103.345 3.6244 110.5366 96.1534
CBA/J m 103.2575 2.5628 108.3427 98.1723
CZECHII/EiJ m 94.455 2.5628 99.5402 89.3698
DBA/2J m 89.3775 2.5628 94.4627 84.2923
FVB/NJ m 98.2825 2.5628 103.3677 93.1973
I/LnJ m 98.4275 2.5628 103.5127 93.3423
KK/HlJ m 90.8725 2.5628 95.9577 85.7873
LG/J m 112.2375 2.5628 117.3227 107.1523
LP/J m 94.85 2.5628 99.9352 89.7648
MA/MyJ m 92.6775 2.5628 97.7627 87.5923
NOD/ShiLtJ m 100.7775 2.5628 105.8627 95.6923
NON/ShiLtJ m 97.865 2.5628 102.9502 92.7798
NZB/BlNJ m 97.0525 2.5628 102.1377 91.9673
NZO/HlLtJ m 92.3875 2.5628 97.4727 87.3023
NZW/LacJ m 96.7075 2.5628 101.7927 91.6223
PERA/EiJ m 103.9975 2.5628 109.0827 98.9123
PL/J m 99.46 2.5628 104.5452 94.3748
PWD/PhJ m 87.91 2.5628 92.9952 82.8248
PWK/PhJ m 98.005 2.5628 103.0902 92.9198
RIIIS/J m 83.3625 2.5628 88.4477 78.2773
SEA/GnJ m 94.95 2.5628 100.0352 89.8648
SJL/J m 80.2775 2.5628 85.3627 75.1923
SM/J m 95.6025 2.5628 100.6877 90.5173
WSB/EiJ m 118.44 2.9593 124.3119 112.5681




  GWAS USING LINEAR MIXED MODELS