Project measure / variable:   Korstanje2   pct_MME_M12

ID, description, units MPD:51002   pct_MME_M12   percentage of glomeruli exhibiting mesangial matrix expansion   [%]  at age 12mo  
Data set, strains Korstanje2   inbred   20 strains     sex: m     age: 52wks
Procedure histopathology
Ontology mappings

  STRAIN COMPARISON PLOT
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Korstanje2 - percentage of glomeruli exhibiting mesangial matrix expansion at age 12mo



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested20 strains
Mean of the strain means8.64   %
Median of the strain means6.33   %
SD of the strain means± 7.37
Coefficient of variation (CV)0.853
Min–max range of strain means1.00   –   29.3   %
Mean sample size per strain5.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 19 5814.0556 306.0029 11.0095 < 0.0001
Residuals 96 2668.275 27.7945


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J m 1.0 1.1   6 0.447 1.1 -1.04
AKR/J m 29.3 6.65   6 2.72 0.227 20.0, 36.0 2.8
BALB/cByJ m 6.33 3.44   6 1.41 0.544 -0.31
BTBR T+ Itpr3tf/J m 2.67 1.63   6 0.667 0.612 -0.81
BUB/BnJ m 2.67 2.42   6 0.989 0.908 -0.81
C57BL/10J m 5.67 4.27   6 1.74 0.754 2.0, 14.0 -0.4
C57BL/6J m 5.0 4.34   6 1.77 0.867 -0.49
C57BR/cdJ m 11.0 7.67   6 3.13 0.697 0.32
C57L/J m 4.67 4.84   6 1.98 1.04 -0.54
CBA/J m 3.33 2.07   6 0.843 0.62 -0.72
FVB/NJ m 2.0 3.1   6 1.26 1.55 -0.9
KK/HlJ m 8.38 5.53   6 2.26 0.659 4.0, 18.0 -0.04
MRL/MpJ m 6.33 2.94   6 1.2 0.465 2.0, 10.0 -0.31
NOD.B10Sn-H2b/J m 9.33 6.15   6 2.51 0.659 0.09
NON/ShiLtJ m 6.67 2.42   6 0.989 0.363 4.0, 10.0 -0.27
NZO/HlLtJ m 21.2 12.2   5 5.46 0.576 12.0, 42.0 1.7
NZW/LacJ m 10.0 4.38   6 1.79 0.438 4.0, 16.0 0.18
P/J m 17.3 10.3   3 5.93 0.592 6.0, 26.0 1.17
PL/J m 2.67 3.93   6 1.61 1.47 -0.81
SM/J m 17.3 7.45   6 3.04 0.43 10.0, 28.0 1.17


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 1.0 2.1523 5.2723 0.0
AKR/J m 29.3333 2.1523 33.6056 25.061
BALB/cByJ m 6.3333 2.1523 10.6056 2.061
BTBR T+ Itpr3tf/J m 2.6667 2.1523 6.939 0.0
BUB/BnJ m 2.6667 2.1523 6.939 0.0
C57BL/10J m 5.6667 2.1523 9.939 1.3944
C57BL/6J m 5.0 2.1523 9.2723 0.7277
C57BR/cdJ m 11.0 2.1523 15.2723 6.7277
C57L/J m 4.6667 2.1523 8.939 0.3944
CBA/J m 3.3333 2.1523 7.6056 0.0
FVB/NJ m 2.0 2.1523 6.2723 0.0
KK/HlJ m 8.3833 2.1523 12.6556 4.111
MRL/MpJ m 6.3333 2.1523 10.6056 2.061
NOD.B10Sn-H2b/J m 9.3333 2.1523 13.6056 5.061
NON/ShiLtJ m 6.6667 2.1523 10.939 2.3944
NZO/HlLtJ m 21.2 2.3577 25.8801 16.5199
NZW/LacJ m 10.0 2.1523 14.2723 5.7277
P/J m 17.3333 3.0438 23.3753 11.2914
PL/J m 2.6667 2.1523 6.939 0.0
SM/J m 17.3333 2.1523 21.6056 13.061




  GWAS USING LINEAR MIXED MODELS