Project measure / variable:   HMDPpheno6   MeB_carnitine

ID, description, units MPD:50173   MeB_carnitine   liver 2-methylbutyroylcarnitine (16h fast), relative abundance    
Data set, strains HMDPpheno6   HMDP w/par   105 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings


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  STRAIN COMPARISON PLOT
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HMDPpheno6 - liver 2-methylbutyroylcarnitine (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested105 strains
Mean of the strain means238084   None
Median of the strain means201208   None
SD of the strain means± 148871
Coefficient of variation (CV)0.625
Min–max range of strain means77218   –   1182245   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 232405261436.583 11066917211.2659 1.9129 0.0449
Residuals 34 196708003699.171 5785529520.5639


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 150006.0 0.0   1   0.0 0.0 150006.0, 150006.0 -0.59
A/J m 155512.0 10990.0   2   7771.0 0.0707 147740.0, 163283.0 -0.55
AKR/J m 171277.0 0.0   1   0.0 0.0 171277.0, 171277.0 -0.45
AXB10/PgnJ m 220846.0 0.0   1   0.0 0.0 220846.0, 220846.0 -0.12
AXB12/PgnJ m 176924.0 0.0   1   0.0 0.0 176924.0, 176924.0 -0.41
AXB13/PgnJ m 101983.0 0.0   1   0.0 0.0 101983.0, 101983.0 -0.91
AXB15/PgnJ m 132297.0 0.0   1   0.0 0.0 132297.0, 132297.0 -0.71
AXB19a/PgnJ m 165487.0 0.0   1   0.0 0.0 165487.0, 165487.0 -0.49
AXB19b/PgnJ m 344854.0 120940.0   2   85518.0 0.351 259336.0, 430372.0 0.72
AXB19/PgnJ m 177855.0 0.0   1   0.0 0.0 177855.0, 177855.0 -0.4
AXB1/PgnJ m 415291.0 0.0   1   0.0 0.0 415291.0, 415291.0 1.19
AXB23/PgnJ m 134090.0 0.0   1   0.0 0.0 134090.0, 134090.0 -0.7
AXB24/PgnJ m 108632.0 8879.0   2   6279.0 0.0817 102353.0, 114910.0 -0.87
AXB2/PgnJ m 152639.0 0.0   1   0.0 0.0 152639.0, 152639.0 -0.57
AXB4/PgnJ m 278880.0 0.0   1   0.0 0.0 278880.0, 278880.0 0.27
AXB5/PgnJ m 81440.0 0.0   1   0.0 0.0 81440.0, 81440.0 -1.05
AXB6/PgnJ m 164590.0 0.0   1   0.0 0.0 164590.0, 164590.0 -0.49
AXB8/PgnJ m 157829.0 0.0   1   0.0 0.0 157829.0, 157829.0 -0.54
BALB/cJ m 136488.0 31099.0   3 17955.0 0.228 101755.0, 161752.0 -0.68
BTBR T+ Itpr3tf/J m 168069.0 0.0   1   0.0 0.0 168069.0, 168069.0 -0.47
BUB/BnJ m 327441.0 0.0   1   0.0 0.0 327441.0, 327441.0 0.6
BXA11/PgnJ m 269026.0 0.0   1   0.0 0.0 269026.0, 269026.0 0.21
BXA12/PgnJ m 146621.0 0.0   1   0.0 0.0 146621.0, 146621.0 -0.61
BXA13/PgnJ m 142392.0 0.0   1   0.0 0.0 142392.0, 142392.0 -0.64
BXA14/PgnJ m 120185.0 0.0   1   0.0 0.0 120185.0, 120185.0 -0.79
BXA16/PgnJ m 250214.0 135920.0   2   96110.0 0.543 154104.0, 346324.0 0.08
BXA1/PgnJ m 160782.0 0.0   1   0.0 0.0 160782.0, 160782.0 -0.52
BXA24/PgnJ m 141899.0 0.0   1   0.0 0.0 141899.0, 141899.0 -0.65
BXA25/PgnJ m 133505.0 0.0   1   0.0 0.0 133505.0, 133505.0 -0.7
BXA26/PgnJ m 239539.0 0.0   1   0.0 0.0 239539.0, 239539.0 0.01
BXA2/PgnJ m 183642.0 0.0   1   0.0 0.0 183642.0, 183642.0 -0.37
BXA4/PgnJ m 155151.0 0.0   1   0.0 0.0 155151.0, 155151.0 -0.56
BXA7/PgnJ m 149386.0 0.0   1   0.0 0.0 149386.0, 149386.0 -0.6
BXA8/PgnJ m 90832.0 0.0   1   0.0 0.0 90832.0, 90832.0 -0.99
BXD11/TyJ m 303149.0 0.0   1   0.0 0.0 303149.0, 303149.0 0.44
BXD12/TyJ m 426740.0 0.0   1   0.0 0.0 426740.0, 426740.0 1.27
BXD13/TyJ m 270670.0 0.0   1   0.0 0.0 270670.0, 270670.0 0.22
BXD14/TyJ m 225539.0 0.0   1   0.0 0.0 225539.0, 225539.0 -0.08
BXD15/TyJ m 486526.0 0.0   1   0.0 0.0 486526.0, 486526.0 1.67
BXD18/TyJ m 207567.0 0.0   1   0.0 0.0 207567.0, 207567.0 -0.2
BXD19/TyJ m 289160.0 97436.0   2   68898.0 0.337 220262.0, 358057.0 0.34
BXD1/TyJ m 321926.0 0.0   1   0.0 0.0 321926.0, 321926.0 0.56
BXD20/TyJ m 482479.0 0.0   1   0.0 0.0 482479.0, 482479.0 1.64
BXD21/TyJ m 323958.0 0.0   1   0.0 0.0 323958.0, 323958.0 0.58
BXD22/TyJ m 262407.0 0.0   1   0.0 0.0 262407.0, 262407.0 0.16
BXD24/TyJ m 280806.0 0.0   1   0.0 0.0 280806.0, 280806.0 0.29
BXD24/TyJ-Cep290rd16/J m 602814.0 0.0   1   0.0 0.0 602814.0, 602814.0 2.45
BXD28/TyJ m 242776.0 47224.0   2   33393.0 0.195 209383.0, 276168.0 0.03
BXD29-Tlr4lps-2J/J m 417408.0 0.0   1   0.0 0.0 417408.0, 417408.0 1.2
BXD2/TyJ m 566934.0 0.0   1   0.0 0.0 566934.0, 566934.0 2.21
BXD32/TyJ m 297390.0 0.0   1   0.0 0.0 297390.0, 297390.0 0.4
BXD33/TyJ m 366394.0 0.0   1   0.0 0.0 366394.0, 366394.0 0.86
BXD34/TyJ m 400314.0 0.0   1   0.0 0.0 400314.0, 400314.0 1.09
BXD36/TyJ m 595293.0 0.0   1   0.0 0.0 595293.0, 595293.0 2.4
BXD38/TyJ m 296452.0 0.0   1   0.0 0.0 296452.0, 296452.0 0.39
BXD39/TyJ m 295906.0 0.0   1   0.0 0.0 295906.0, 295906.0 0.39
BXD40/TyJ m 389427.0 0.0   1   0.0 0.0 389427.0, 389427.0 1.02
BXD42/TyJ m 488101.0 0.0   1   0.0 0.0 488101.0, 488101.0 1.68
BXD5/TyJ m 196263.0 0.0   1   0.0 0.0 196263.0, 196263.0 -0.28
BXD6/TyJ m 415122.0 0.0   1   0.0 0.0 415122.0, 415122.0 1.19
BXD8/TyJ m 240893.0 0.0   1   0.0 0.0 240893.0, 240893.0 0.02
BXD9/TyJ m 410187.0 0.0   1   0.0 0.0 410187.0, 410187.0 1.16
BXH10/TyJ m 162089.0 0.0   1   0.0 0.0 162089.0, 162089.0 -0.51
BXH19/TyJ m 117594.0 0.0   1   0.0 0.0 117594.0, 117594.0 -0.81
BXH20/KccJ m 211908.0 0.0   1   0.0 0.0 211908.0, 211908.0 -0.18
BXH22/KccJ m 244687.0 0.0   1   0.0 0.0 244687.0, 244687.0 0.04
BXH2/TyJ m 201608.0 0.0   1   0.0 0.0 201608.0, 201608.0 -0.25
BXH4/TyJ m 158923.0 37710.0   2   26665.0 0.237 132258.0, 185588.0 -0.53
BXH6/TyJ m 191962.0 0.0   1   0.0 0.0 191962.0, 191962.0 -0.31
BXH7/TyJ m 423606.0 0.0   1   0.0 0.0 423606.0, 423606.0 1.25
BXH8/TyJ m 121168.0 0.0   1   0.0 0.0 121168.0, 121168.0 -0.79
BXH9/TyJ m 235451.0 0.0   1   0.0 0.0 235451.0, 235451.0 -0.02
C3H/HeJ m 206856.0 57827.0   2   40890.0 0.28 165966.0, 247746.0 -0.21
C57BL/6J m 220777.0 95075.0   5 42519.0 0.431 109096.0, 352999.0 -0.12
C57L/J m 175755.0 0.0   1   0.0 0.0 175755.0, 175755.0 -0.42
C58/J m 1182245.0 0.0   1   0.0 0.0 1182245.0, 1182245.0 6.34
CAST/EiJ m 171415.0 0.0   1   0.0 0.0 171415.0, 171415.0 -0.45
CBA/J m 90216.0 0.0   1   0.0 0.0 90216.0, 90216.0 -0.99
CE/J m 151087.0 0.0   1   0.0 0.0 151087.0, 151087.0 -0.58
CXB11/HiAJ m 217978.0 133551.0   2   94435.0 0.613 123543.0, 312412.0 -0.14
CXB12/HiAJ m 225145.0 68193.0   2   48219.0 0.303 176925.0, 273364.0 -0.09
CXB13/HiAJ m 253028.0 27187.0   3 15697.0 0.107 223742.0, 277463.0 0.1
CXB1/ByJ m 91879.0 34550.0   3 19948.0 0.376 58814.0, 127744.0 -0.98
CXB2/ByJ m 218112.0 130038.0   3 75078.0 0.596 134112.0, 367898.0 -0.13
CXB3/ByJ m 165532.0 20861.0   2   14751.0 0.126 150781.0, 180284.0 -0.49
CXB4/ByJ m 136530.0 66628.0   2   47113.0 0.488 89417.0, 183642.0 -0.68
CXB6/ByJ m 201208.0 38925.0   3 22473.0 0.193 174979.0, 245932.0 -0.25
CXB7/ByJ m 126724.0 46824.0   2   33110.0 0.369 93615.0, 159834.0 -0.75
CXB8/HiAJ m 121770.0 40096.0   3 23150.0 0.329 75729.0, 149016.0 -0.78
CXB9/HiAJ m 101565.0 70455.0   3 40677.0 0.694 36456.0, 176363.0 -0.92
DBA/2J m 262357.0 92040.0   4 46020.0 0.351 152292.0, 363654.0 0.16
FVB/NJ m 306378.0 0.0   1   0.0 0.0 306378.0, 306378.0 0.46
I/LnJ m 161399.0 0.0   1   0.0 0.0 161399.0, 161399.0 -0.52
KK/HlJ m 81826.0 0.0   1   0.0 0.0 81826.0, 81826.0 -1.05
LG/J m 156863.0 0.0   1   0.0 0.0 156863.0, 156863.0 -0.55
LP/J m 245303.0 0.0   1   0.0 0.0 245303.0, 245303.0 0.05
MA/MyJ m 77218.0 0.0   1   0.0 0.0 77218.0, 77218.0 -1.08
NOD/ShiLtJ m 131988.0 0.0   1   0.0 0.0 131988.0, 131988.0 -0.71
NON/ShiLtJ m 117357.0 0.0   1   0.0 0.0 117357.0, 117357.0 -0.81
NZW/LacJ m 161190.0 0.0   1   0.0 0.0 161190.0, 161190.0 -0.52
PL/J m 106274.0 0.0   1   0.0 0.0 106274.0, 106274.0 -0.89
RIIIS/J m 161903.0 0.0   1   0.0 0.0 161903.0, 161903.0 -0.51
SEA/GnJ m 193816.0 0.0   1   0.0 0.0 193816.0, 193816.0 -0.3
SM/J m 285830.0 0.0   1   0.0 0.0 285830.0, 285830.0 0.32
SWR/J m 214098.0 0.0   1   0.0 0.0 214098.0, 214098.0 -0.16


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 155511.55 53784.4286 264814.6597 46208.4403
AXB19b/PgnJ m 344854.15 53784.4286 454157.2597 235551.0403
AXB24/PgnJ m 108631.8 53784.4286 217934.9097 0.0
BALB/cJ m 136487.5333 43914.8021 225733.1487 47241.918
BXA16/PgnJ m 250214.15 53784.4286 359517.2597 140911.0403
BXD19/TyJ m 289159.55 53784.4286 398462.6597 179856.4403
BXD28/TyJ m 242775.6 53784.4286 352078.7097 133472.4903
BXH4/TyJ m 158922.6 53784.4286 268225.7097 49619.4903
C3H/HeJ m 206855.6 53784.4286 316158.7097 97552.4903
C57BL/6J m 220776.92 34016.2594 289906.2764 151647.5636
CXB11/HiAJ m 217977.5 53784.4286 327280.6097 108674.3903
CXB12/HiAJ m 225144.7 53784.4286 334447.8097 115841.5903
CXB13/HiAJ m 253027.6333 43914.8021 342273.2487 163782.018
CXB1/ByJ m 91879.2333 43914.8021 181124.8487 2633.618
CXB2/ByJ m 218111.6 43914.8021 307357.2154 128865.9846
CXB3/ByJ m 165532.3 53784.4286 274835.4097 56229.1903
CXB4/ByJ m 136529.65 53784.4286 245832.7597 27226.5403
CXB6/ByJ m 201207.7 43914.8021 290453.3154 111962.0846
CXB7/ByJ m 126724.35 53784.4286 236027.4597 17421.2403
CXB8/HiAJ m 121770.2333 43914.8021 211015.8487 32524.618
CXB9/HiAJ m 101565.2667 43914.8021 190810.882 12319.6513
DBA/2J m 262356.8 38031.3342 339645.7701 185067.8299




  GWAS USING LINEAR MIXED MODELS